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NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

ID: PAR-25-333 • Type: Posted
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Description

Posted: June 17, 2025, 12:00 a.m. EDT
The purpose of the NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) program is to develop and maintain a strong cohort of independently funded dentist scientists dedicated to improving dental, oral and craniofacial health. This program is designed to facilitate a timely transition of outstanding dual degree dentist scientists from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions by providing support for two years of mentored training and three to five years of independent research. An option for five years of independent (R00) support is available to accommodate clinical training in a dental specialty program at no more than 3 person-months effort (25% full-time professional effort) in any year of the R00 phase.
Posted: May 6, 2025, 12:00 a.m. EDT
Posted: May 6, 2025, 12:00 a.m. EDT
Posted: May 6, 2025, 12:00 a.m. EDT
Background
The NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) program, issued by the National Institute of Dental and Craniofacial Research (NIDCR), aims to develop a strong cohort of independently funded dentist scientists focused on improving dental, oral, and craniofacial health. This initiative facilitates the transition of dual degree dentist scientists from mentored postdoctoral positions to independent faculty roles by providing support for two years of mentored training and three to five years of independent research.

Grant Details
The K99/R00 award consists of two phases: the K99 phase provides up to 2 years of mentored postdoctoral research training, while the R00 phase offers 3 to 5 years of independent research support. The program is specifically designed for candidates who do not lead independent clinical trials but may propose research experiences in clinical trials led by mentors. Candidates must have a clinical DDS or DMD degree and a PhD or equivalent. The award supports up to $100,000 per year for salary during the K99 phase and up to $249,000 per year during the R00 phase, which includes salary and research costs. Candidates pursuing dental specialty training during the R00 phase may receive up to 5 years of support if they maintain at least 75% full-time professional effort on research activities.

Eligibility Requirements
Eligible applicants must hold both a clinical DDS or DMD degree and a PhD or equivalent. They should have no more than 4 years of postdoctoral research experience at the time of application. Candidates must be in mentored postdoctoral positions; those who achieve independence before receiving the K99 award are not eligible. There are no citizenship requirements; both U.S. citizens and non-citizen nationals can apply.

Period of Performance
The total project period may not exceed 7 years, consisting of a maximum of 2 years for the K99 phase followed by either 3 or 5 years for the R00 phase.

Grant Value
The total value of the grant can reach up to $1,745,000 over its duration, with individual awards potentially reaching $249,000 per year during the R00 phase.

Place of Performance
The grant will be performed at institutions that can provide appropriate infrastructure for research support and career development.

Overview

Category of Funding
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 6/17/25 the National Institutes of Health posted grant opportunity PAR-25-333 for NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed). The grant will be issued under grant program 93.121 Oral Diseases and Disorders Research.

Timing

Posted Date
June 17, 2025, 12:00 a.m. EDT
Closing Date
May 7, 2028, 12:00 a.m. EDT Due in 979 Days
Last Updated
June 17, 2025, 2:08 p.m. EDT
Version
1
Archive Date
June 12, 2028

Eligibility

Eligible Applicants
Special district governments
Public and State controlled institutions of higher education
For profit organizations other than small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Native American tribal governments (Federally recognized)
Private institutions of higher education
Independent school districts
Native American tribal organizations (other than Federally recognized tribal governments)
State governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
City or township governments
Public housing authorities/Indian housing authorities
Small businesses
Additional Info
Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Contacts

Contact
National Institutes of Health
Contact Email
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/pa-files/PAR-25-333.html

Documents

Posted documents for PAR-25-333

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