National Dental Practice-Based Research Network: Coordinating Center (U01 Clinical Trial Required )

The National Institute of Dental and Craniofacial Research (NIDCR) intends to continue support for research conducted within a national Dental Practice-Based Research Network (DPBRN). The NIDCR will fund one national DPBRN Administrative and Resource Center led by a National Network Director and one national DPBRN Coordinating Center, funded as companion awards, to support the infrastructure for and implementation of multiple prospective observational studies and clinical trials. This funding opportunity announcement (FOA) is soliciting applications for the national DPBRN Coordinating Center; a separate FOA is soliciting applications for the national DPBRN Administrative and Resource Center (RFA-DE-19-002 ). This clinical research network will develop and conduct multiple prospective, observational clinical studies and clinical trials, on topics of interest to practitioners and their patients. Studies will be conducted in participating dental offices with consenting patients. The role of the national Coordinating Center will be to centralize and harmonize study operations, data management, and biostatistical support, to facilitate rapid development and implementation of oral health studies conducted in the national DPBRN.