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Feasibility Studies that Explore Healthy and Diseased Temporomandibular Joints (TMJ) using Single Cell Multi-Omic Analyses (UH2/UH3 Clinical Trial Not Allowed)

ID: RFA-DE-22-005 • Type: Posted
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Description

The goal of this initiative is to encourage research focused on deciphering the cellular and molecular mechanisms underpinning temporomandibular joint disorders (TMJD) pain and tissue dysfunction using single-cell omics approaches. Delineation of cellular and molecular mechanisms that mediate TMJD resolution and homeostasis are also desired. Identification of cell populations and their effector pathways, in TMJD target tissue (e.g. synovial fluid, muscle, skin), as 1) molecular disease classifiers allowing for patient stratification, 2) diagnostic, prognostic, and/or predictive biomarkers, and/or 3) novel therapeutic targets are desired outcomes of this initiative.

Overview

Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 8/12/21 the National Institutes of Health posted grant opportunity RFA-DE-22-005 for Feasibility Studies that Explore Healthy and Diseased Temporomandibular Joints (TMJ) using Single Cell Multi-Omic Analyses (UH2/UH3 Clinical Trial Not Allowed). The grant will be issued under grant program 93.121 Oral Diseases and Disorders Research.

Timing

Posted Date
Aug. 12, 2021, 12:00 a.m. EDT
Closing Date
Nov. 10, 2021, 12:00 a.m. EST Past Due
Last Updated
Aug. 12, 2021, 12:01 p.m. EDT
Version
1
Archive Date
Dec. 16, 2021

Eligibility

Eligible Applicants
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
Special district governments
City or township governments
County governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education
Private institutions of higher education
State governments
Public housing authorities/Indian housing authorities
Small businesses
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
For profit organizations other than small businesses
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Contacts

Contact
National Institutes of Health
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541

Documents

Posted documents for RFA-DE-22-005

Grant Awards

Grants awarded through RFA-DE-22-005

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