Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)

Background
The purpose of this Notice of Funding Opportunity (NOFO) is to support established biomedical data resources, that have demonstrated impact and have potential for continued benefit to the mission of one or more of the NIH Institutes and Centers participating in this announcement. The funding opportunity announcements were first launched in 2019 to realize NIH's vision for a modernized biomedical data ecosystem as outlined in NIH’s Strategic Plan for Data Science.

The funding opportunities were reissued in 2023 to align with the NIH Data Management and Sharing Policy.

Grant Details
Each resource must: (a) deliver scientific impact to the communities served; (b) employ and promote good data management practices (as outlined by the FAIR Data Principles including adherence to the NIH desirable characteristics of repositories) and efficient operations for quality and services; (c) engage with the user community and continuously address their needs; and (d) support a process for data life-cycle analysis, long-term preservation, and trustworthy governance. The evaluation of the repositories will be based on their usage, utility, impact, quality of data and services, and efficiency of operations, community needs and engagement, trustworthiness of stewardship, and governance.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, state governments, federal governments, U.S. territories or possessions, Indian/Native American tribal governments (federally recognized), independent school districts, public housing authorities/Indian housing authorities, Native American tribal organizations (other than federally recognized tribal governments), faith-based or community-based organizations, regional organizations, non-domestic (non-U.S.) entities (foreign institutions), foreign components of U.S. Organizations.

Period of Performance
Applications may request up to five (5) years of support for an established biomedical data repository or knowledgebase.

Grant Value
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. ODSS anticipates co-funding applications funded by Institutes/Centers/Offices based on program priorities and relevance to more than one NIH Institute/Center/Office. NINDS intends to support up to 2 awards in each fiscal year.