Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)

Background
The National Institutes of Health (NIH), specifically the National Institute of Dental and Craniofacial Research (NIDCR), is issuing this Notice of Funding Opportunity (NOFO) to solicit UG3/UH3 phased cooperative agreement research applications. The goal is to evaluate, implement, and/or test population-based interventions that promote the integration of services, systems, and values through cross-sector partnerships in communities. This initiative aims to address social and chronic disease common risk factors driving oral disease burden, ultimately optimizing oral health for all individuals across their lifespan.

Grant Details
The funded projects will form a Community-Based Participatory Research (CBPR) consortium called Advancing Data and Practice Transformation (ADAPT). The projects must evaluate, implement, and/or test interventions at community or societal levels that address social and chronic disease common risk factors impacting oral health. Key tasks include:
1) Conducting developmental studies during the UG3 phase to demonstrate feasibility;
2) Transitioning to the UH3 phase for testing/evaluating interventions;
3) Engaging in cross-sector partnerships;
4) Collecting core common data elements using NIH resources;
5) Focusing on populations experiencing chronic oral disease burdens;
6) Utilizing a theory-driven framework for intervention design;
7) Collaborating with community representatives throughout the research process.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, local/state governments, Indian/Native American tribal governments, and faith-based organizations. Multiple project directors/principal investigators from both research and community partner organizations are encouraged. Non-domestic entities are not eligible to apply.

Period of Performance
The maximum project period is seven years: two years for the UG3 phase and five years for the UH3 phase.

Grant Value
The budget for UG3 applications is limited to $300,000 per year in direct costs, while UH3 applications can request up to $650,000 per year in direct costs.

Place of Performance
The specific geographic locations for performance should focus on communities experiencing high burdens of oral disease.