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BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed)

ID: RFA-MH-25-115 • Type: Posted
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Description

The common marmoset (Callithrix jacchus) has emerged as a promising nonhuman primate model system to understand the primate brain. This has come about both from the realization that the behavior of the common marmoset is similar in some ways to human behavior and from recent demonstration of germline transmission of exogenous genetic information. This Notice of Funding Opportunity (NOFO) solicits applications to expand existing colonies of the common marmoset for neuroscience research in the United States, and to support the care, breeding and distribution of genetically modified marmosets, and cryopreserved embryos and gametes created by NIH-funded research programs such as the NIH BRAIN Initiative Tools for Germline Gene Editing in Marmosets research consortium. Recipients s under this NOFO are expected to expand their current marmoset colonies to provide healthy, well-characterized animals that will be made available to the neuroscience research community, and to include a plan to accept genetically modified marmosets, and cryopreserved embryos and gametes for distribution to the research community. Recipients are also expected to participate in and provide health and genetic information to an NIH-Funded Marmoset Coordination Center to help the community understand the pedigree of individuals in the captive marmoset population and improve the genetic diversity of that population across multiple colonies.
Background
The National Institutes of Health (NIH) has issued a Notice of Funding Opportunity (NOFO) to expand existing colonies of the common marmoset for neuroscience research in the United States. The goal is to provide healthy, well-characterized animals to the neuroscience research community and support the care, breeding, and distribution of genetically modified marmosets, cryopreserved embryos, and gametes created by NIH-funded research programs such as the NIH BRAIN Initiative Tools for Germline Gene Editing in Marmosets research consortium.

Grant Details
The recipients under this NOFO are expected to expand their current marmoset colonies and participate in providing health and genetic information to an NIH-Funded Marmoset Coordination Center. They are also required to propose animal husbandry questions related to housing, feeding, transportation, and establishment of marmosets at new sites. The NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP) which will be assessed as part of the scientific and technical peer review evaluation.

Eligibility Requirements
All organizations administering an eligible parent award may apply for a supplement under this NOFO. Eligible organizations include higher education institutions, nonprofits, for-profit organizations, state and local governments, federally recognized Indian/Native American tribal governments, and others. Foreign organizations are not eligible to apply.

Period of Performance
The project period is up to 5 years with an earliest start date of March 1, 2024. The application due date is February 1, 2024. The total estimated funding available for FY25 is $2M to fund 1-3 awards.

Grant Value
Application budgets are not limited but need to reflect the actual needs of the proposed project. The total value of individual grant awards will depend on the proposed project scope.

Place of Performance
The grant will be performed in the United States.

Overview

On 11/28/23 the National Institutes of Health posted grant opportunity RFA-MH-25-115 for BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed). The grant will be issued under grant program 93.113 Environmental Health.

Timing

Posted Date
Nov. 28, 2023, 12:00 a.m. EST
Closing Date
March 1, 2024, 12:00 a.m. EST Past Due
Last Updated
Nov. 28, 2023, 12:10 p.m. EST
Version
1
Archive Date
April 6, 2024

Eligibility

Eligible Applicants
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
City or township governments
Public and State controlled institutions of higher education
County governments
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Independent school districts
Private institutions of higher education
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Contacts

Contact
National Institutes of Health
Contact Email
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-115.html

Documents

Posted documents for RFA-MH-25-115

Grant Awards

Grants awarded through RFA-MH-25-115

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