Twist Bioscience Reagents

Background
The contract is issued by the Laboratory Services Division under the Genomic Surveillance Program, specifically for the Sequencing and Wastewater Unit. The goal of this contract is to procure synthetic viral assay controls and custom hybrid panels from Twist Biosciences, which are essential for laboratories conducting quantitative RT-PCR, dPCR, NGS, or equivalent tests.

Twist Biosciences has developed a proprietary semiconductor-based synthetic DNA and RNA manufacturing process that provides high-fidelity controls necessary for accurate testing in laboratories lacking biosafety containment facilities.

Work Details
The products and services to be procured include synthetic DNA/RNA controls and custom proprietary Hyb Cap panels developed by Twist Biosciences. These controls are designed to meet equivalency standards for laboratories performing various assays.

The current quote request totals $891,380. The estimated dollar amount for the life of the project is $2.3 million over a period of five years, with routine testing costs projected at $350K per year. Each control is priced at approximately $3,090.

Period of Performance
The contract will commence on May 15, 2026, and will end on May 14, 2030.

Place of Performance
The products will be delivered to laboratories that require synthetic viral assay controls, specifically mentioned is the Colorado Department of Public Health and Environment (CDPHE).

Bidder Requirements
Twist Biosciences is identified as the sole source vendor due to their unique capability in producing high-fidelity synthetic viral pathogen controls necessary for quality assurance in testing. No specific certifications or licenses beyond those inherent to their proprietary technology are required.