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UM1TR004407

Cooperative Agreement

Overview

Grant Description
Scripps Clinical and Translational Science Hub - Project Summary / Abstract

The Scripps Research Translational Institute (SRTI) is the foundation for the Scripps Hub and is dedicated to accelerating science that will improve human health. SRTI's emphasis on genomics, digital medicine, and informatics/analytics fosters a multi-dimensional understanding of individualized human health.

The Scripps Hub has previously included the Scripps Research Institute (SR) and Scripps Health (SH) as principal partners, including Rady Children's Institute of Genomic Medicine (RCIGM) for genomic medicine initiatives and California Institute for Medical Research (Calibr) for drug repurposing/discovery. In the new CTSA cycle, our partners have expanded to include San Diego State University (SDSU), enabling us to combine forces in computer science, artificial intelligence, biosensors, and diversity inclusion and equity initiatives.

SRTI's expertise in genomics was highlighted during the pandemic. We became one of the country's most productive sequencing centers for SARS-CoV-2 by rapidly forming the "SEARCH" alliance to process samples with the San Diego County Department of Health, UCSD, Sharp Health, California Department of Public Health, Helix, and our partners RCIGM and SH.

Digital medicine has been one of SRTI's core strengths, having pioneered the first remote, site-less digital clinical trial and now expanding this methodology to address many other medical conditions such as health during pregnancy and sleep disorders. Our Digital Trials Center launched the Digital Engagement & Tracking for Early Control and Treatment Scripps (DETECT) study, and in a matter of weeks, our team was able to accurately predict the likelihood of COVID with SARS-CoV-2 using passively collected resting heart rate data from wristband sensors and later to identify a physiologic signature that correlates with long COVID (post-acute sequelae or SARS-CoV-2 infection).

The Scripps Hub will innovate clinical and translational science to improve human health across the lifespan and diverse racial, ethnic, geographic, and socioeconomic communities. The Hub will provide a nurturing environment for education, training, and career development with a focus on individualized health domains of genomics, digital medicine, and biomedical informatics, to empower tomorrow's diverse workforce.
Funding Goals
NOT APPLICABLE
Place of Performance
La Jolla, California 920371000 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have decreased from $12,059,584 to $12,035,412.
Scripps Research Institute was awarded Scripps Clinical & Translational Science Hub - Improving Human Health Cooperative Agreement UM1TR004407 worth $12,035,412 from National Center for Advancing Translational Sciences in May 2023 with work to be completed primarily in La Jolla California United States. The grant has a duration of 7 years and was awarded through assistance program 93.350 National Center for Advancing Translational Sciences. The Cooperative Agreement was awarded through grant opportunity Clinical and Translational Science Award (UM1 Clinical Trial Optional).

Status
(Ongoing)

Last Modified 7/19/24

Period of Performance
5/1/23
Start Date
4/30/30
End Date
29.0% Complete

Funding Split
$12.0M
Federal Obligation
$0.0
Non-Federal Obligation
$12.0M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to UM1TR004407

Transaction History

Modifications to UM1TR004407

Additional Detail

Award ID FAIN
UM1TR004407
SAI Number
UM1TR004407-1200943079
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Nonprofit With 501(c)(3) IRS Status (Other Than An Institution Of Higher Education)
Awarding Office
75NR00 NIH NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
Funding Office
75NR00 NIH NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
Awardee UEI
PHZJFZ32NKH4
Awardee CAGE
08PA3
Performance District
CA-50
Senators
Dianne Feinstein
Alejandro Padilla

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Center for Advancing Translational Sciences, National Institutes of Health, Health and Human Services (075-0875) Health research and training Grants, subsidies, and contributions (41.0) $6,029,792 100%
Modified: 7/19/24