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U54HD113173

Cooperative Agreement

Overview

Grant Description
Center for Indigenous Resilience, Culture, and Maternal Health Equity - Project Summary/Abstract

Indigenous mothers (those who self-identify as American Indian, Alaskan Native, or Native American) experience the highest rates of maternal mortality and morbidity (MMM) in the U.S. Structural, social, and biobehavioral factors driving these inequities, such as food insecurity induced by food apartheid, chronic stress perpetuated through intergenerational trauma, and loss of traditional birthing practices and roles, require innovative solutions.

To accomplish this, the Center for Indigenous Resilience, Culture, and Maternal Health Equity (CIRCLE) has been formed to better understand and address these factors through individual, family, community, and health systems interventions. The long-term goal of the CIRCLE is to eliminate disparities in Indigenous MMM through effective translational science spanning best practices in preconception, prenatal, and maternal postpartum care through the first 2 years of life.

The immediate goal of the CIRCLE is to bring together researchers and community partners in Oklahoma/Southern Plains region to discover the sources of Indigenous MMM disparities and translate scientific results into solutions that eliminate maternal health inequities. The CIRCLE will:

(1) Leverage existing and expand current partnerships with tribal health partners on patient-centered outcomes research and interventions;
(2) Cultivate and support an interdisciplinary team of independent experts focused on discovering the bases for, and solutions to, Indigenous maternal health disparities;
(3) Establish the foundation and initial processes necessary to enable translational research and interventions focused on eliminating Indigenous maternal health disparities; and
(4) Exchange strategies, data, findings, and recommendations from Aims 1-3 with key partners.

Achieving the aims of the CIRCLE is significant. Over 90 percent of Indigenous maternal deaths in the U.S. are preventable. Reducing MMM and achieving maternal health equity are a national priority. An essential step in reducing MMM and assuring maternal health equity in the future is the elimination of Indigenous maternal health inequities. The CIRCLE's focus on identifying solutions for Indigenous maternal health disparities therefore addresses a critical barrier to achieving a national public health priority.

The CIRCLE is innovative. Research centers focused on maternal health disparities and inequities exist throughout the country; however, none of these centers focus specifically on Indigenous maternal health. We also emphasize a strengths-based "culture as protective" approach at the core of the CIRCLE.
Funding Goals
TO CONDUCT AND SUPPORT LABORATORY RESEARCH, CLINICAL TRIALS, AND STUDIES WITH PEOPLE THAT EXPLORE HEALTH PROCESSES. NICHD RESEARCHERS EXAMINE GROWTH AND DEVELOPMENT, BIOLOGIC AND REPRODUCTIVE FUNCTIONS, BEHAVIOR PATTERNS, AND POPULATION DYNAMICS TO PROTECT AND MAINTAIN THE HEALTH OF ALL PEOPLE. TO EXAMINE THE IMPACT OF DISABILITIES, DISEASES, AND DEFECTS ON THE LIVES OF INDIVIDUALS. WITH THIS INFORMATION, THE NICHD HOPES TO RESTORE, INCREASE, AND MAXIMIZE THE CAPABILITIES OF PEOPLE AFFECTED BY DISEASE AND INJURY. TO SPONSOR TRAINING PROGRAMS FOR SCIENTISTS, DOCTORS, AND RESEARCHERS TO ENSURE THAT NICHD RESEARCH CAN CONTINUE. BY TRAINING THESE PROFESSIONALS IN THE LATEST RESEARCH METHODS AND TECHNOLOGIES, THE NICHD WILL BE ABLE TO CONDUCT ITS RESEARCH AND MAKE HEALTH RESEARCH PROGRESS UNTIL ALL CHILDREN, ADULTS, FAMILIES, AND POPULATIONS ENJOY GOOD HEALTH. THE MISSION OF THE NICHD IS TO ENSURE THAT EVERY PERSON IS BORN HEALTHY AND WANTED, THAT WOMEN SUFFER NO HARMFUL EFFECTS FROM REPRODUCTIVE PROCESSES, AND THAT ALL CHILDREN HAVE THE CHANCE TO ACHIEVE THEIR FULL POTENTIAL FOR HEALTHY AND PRODUCTIVE LIVES, FREE FROM DISEASE OR DISABILITY, AND TO ENSURE THE HEALTH, PRODUCTIVITY, INDEPENDENCE, AND WELL-BEING OF ALL PEOPLE THROUGH OPTIMAL REHABILITATION.
Place of Performance
Oklahoma City, Oklahoma 73104 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 196% from $1,573,843 to $4,660,677.
University Of Oklahoma was awarded Indigenous Maternal Health Equity Initiative Cooperative Agreement U54HD113173 worth $4,660,677 from the National Institute of Child Health and Human Development in August 2023 with work to be completed primarily in Oklahoma City Oklahoma United States. The grant has a duration of 7 years and was awarded through assistance program 93.865 Child Health and Human Development Extramural Research. The Cooperative Agreement was awarded through grant opportunity Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional).

Status
(Ongoing)

Last Modified 9/5/25

Period of Performance
8/17/23
Start Date
7/31/30
End Date
31.0% Complete

Funding Split
$4.7M
Federal Obligation
$0.0
Non-Federal Obligation
$4.7M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to U54HD113173

Subgrant Awards

Disclosed subgrants for U54HD113173

Transaction History

Modifications to U54HD113173

Additional Detail

Award ID FAIN
U54HD113173
SAI Number
U54HD113173-2190487442
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NT00 NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development
Funding Office
75NT00 NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development
Awardee UEI
GY8NMUZQXVS7
Awardee CAGE
4B862
Performance District
OK-05
Senators
James Lankford
Markwayne Mullin

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute of Child Health and Human Development, National Institutes of Health, Health and Human Services (075-0844) Health research and training Grants, subsidies, and contributions (41.0) $1,573,843 100%
Modified: 9/5/25