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U54CA274513

Cooperative Agreement

Overview

Grant Description
Genomic and microenvironmental determinants, temporal dynamics, and treatment efficacy of radiation-based combination therapies.
Funding Goals
TO PROVIDE AN ORGANIZATIONAL FOCUS AND STIMULUS FOR THE HIGHEST QUALITY CANCER RESEARCH THAT EFFECTIVELY PROMOTES INTERDISCIPLINARY CANCER RESEARCH AIMED TOWARD THE ULTIMATE GOAL OF REDUCING CANCER INCIDENCE, MORTALITY AND MORBIDITY. THE CANCER CENTER SUPPORT GRANT (CCSG) PROVIDES THE RESOURCES AND INFRASTRUCTURE TO FACILITATE THE COORDINATION OF INTERDISCIPLINARY PROGRAMS ACROSS A BROAD SPECTRUM OF RESEARCH FROM BASIC LABORATORY RESEARCH TO CLINICAL INVESTIGATION TO POPULATION SCIENCE. THE CCSG SUPPORTS SALARIES FOR SCIENTIFIC LEADERSHIP OF THE CENTER, SHARED RESOURCES FOR FUNDED CENTER INVESTIGATORS, CERTAIN ADMINISTRATIVE COSTS, PLANNING AND EVALUATION, AND DEVELOPMENTAL FUNDS FOR NEW RECRUITMENTS AND FEASIBILITY STUDIES.
Place of Performance
Cleveland, Ohio 44195 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the End Date has been shortened from 08/31/27 to 07/31/27 and the total obligations have increased 203% from $1,566,249 to $4,740,719.
Cleveland Clinic Lerner College Of Medicine Of Case Western Reserve University was awarded Cooperative Agreement U54CA274513 worth $4,740,719 from National Cancer Institute in September 2022 with work to be completed primarily in Cleveland Ohio United States. The grant has a duration of 4 years 10 months and was awarded through assistance program 93.397 Cancer Centers Support Grants. The Cooperative Agreement was awarded through grant opportunity Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required).

Status
(Ongoing)

Last Modified 5/5/25

Period of Performance
9/14/22
Start Date
7/31/27
End Date
55.0% Complete

Funding Split
$4.7M
Federal Obligation
$0.0
Non-Federal Obligation
$4.7M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to U54CA274513

Subgrant Awards

Disclosed subgrants for U54CA274513

Transaction History

Modifications to U54CA274513

Additional Detail

Award ID FAIN
U54CA274513
SAI Number
U54CA274513-2435683527
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NC00 NIH National Cancer Institute
Funding Office
75NC00 NIH National Cancer Institute
Awardee UEI
M5QFLTCTSQN6
Awardee CAGE
0ZV10
Performance District
OH-11
Senators
Sherrod Brown
J.D. (James) Vance

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Cancer Institute, National Institutes of Health, Health and Human Services (075-0849) Health research and training Grants, subsidies, and contributions (41.0) $3,214,384 100%
Modified: 5/5/25