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U54CA224019

Cooperative Agreement

Overview

Grant Description
Tumor intrinsic and microenvironmental mechanisms driving drug combination efficacy and resistance in AML.
Awardee
Oregon Health & Science University
Funding Goals
NOT APPLICABLE
Grant Program (CFDA)
93.310 - Trans-NIH Research Support
Awarding Agency
National Cancer Institute (NCI) [HHS - NIH]
Funding Agency
National Institute of Allergy and Infectious Diseases (NIAID) [HHS - NIH]
Place of Performance
Portland, Oregon 972393011 United States
Geographic Scope
Single Zip Code
Related Opportunity
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) (PA-20-272)
Analysis Notes
Amendment Since initial award the End Date has been extended from 08/31/19 to 08/31/27 and the total obligations have increased 384% from $2,309,994 to $11,169,693.
Oregon Health & Science University was awarded Architecture and Trajectory of Acquired Resistance to Therapy in AML Cooperative Agreement U54CA224019 worth $11,169,693 from the National Institute of Allergy and Infectious Diseases in September 2017 with work to be completed primarily in Portland Oregon United States. The grant has a duration of 10 years and was awarded through assistance program 93.310 Trans-NIH Research Support. The Cooperative Agreement was awarded through grant opportunity Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional).

Status
(Ongoing)

Last Modified 9/26/25

Period of Performance
9/30/17
Start Date
8/31/27
End Date
83.0% Complete

Funding Split
$11.2M
Federal Obligation
$0.0
Non-Federal Obligation
$11.2M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to U54CA224019

Transaction History

Modifications to U54CA224019

Additional Detail

Award ID FAIN
U54CA224019
SAI Number
U54CA224019-570172599
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NC00 NIH National Cancer Institute
Funding Office
75NA00 NIH OFFICE OF THE DIRECTOR
Awardee UEI
NPSNT86JKN51
Awardee CAGE
0YUJ3
Performance District
OR-01
Senators
Jeff Merkley
Ron Wyden

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Cancer Institute, National Institutes of Health, Health and Human Services (075-0849) Health research and training Grants, subsidies, and contributions (41.0) $10,889,642 100%
Modified: 9/26/25