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U42OD035737

Cooperative Agreement

Overview

Grant Description
Center for Somatic Cell Genome Editing in Nonhuman Primates - Overall Project Summary / Abstract

The Center for Somatic Cell Genome Editing in Nonhuman Primates will fully support studies that will advance the somatic cell genome editing field, and significantly contribute to the future translation of new and emerging technologies for the treatment of human diseases.

The Nonhuman Primate Testing Center brings together a robust team of multidisciplinary investigators with partnerships that capitalize on major strengths at UC Davis including the California National Primate Research Center, Genome Center, and Clinical and Translational Science Center.

The program will provide unique state-of-the-art capabilities for investigators to conduct high-quality research in nonhuman primates.

The Nonhuman Primate Testing Center leverages a supportive framework that has demonstrated a long-standing commitment to outreach and providing collaborative opportunities to investigators nationwide to advance their translational preclinical research goals, including progression to human clinical trials.

Through this powerful and proven infrastructure, the Center for Somatic Cell Genome Editing in Nonhuman Primates will address the following specific aims:

(1) Provide an administrative and organizational structure to advance somatic cell genome editing studies targeting a range of human diseases in all age groups,

(2) Partner with investigators to accelerate their translational research objectives, and

(3) Ensure synergism and sharing across the small and large animal testing centers and transparent interactions with the research community and the NIH.

Our robust multidisciplinary team is poised to continue our national role and service to the research community by bringing the depth and breadth of opportunities available to support investigators, and safely advance somatic cell genome editing technologies to new treatments for human diseases.
Funding Goals
THE OFFICE OF RESEARCH INFRASTRUCTURE PROGRAMS (ORIP) IS A PROGRAM OFFICE IN THE DIVISION OF PROGRAM COORDINATION, PLANNING, AND STRATEGIC INITIATIVES (DPCPSI) DEDICATED TO SUPPORTING RESEARCH INFRASTRUCTURE AND RELATED RESEARCH RESOURCE PROGRAMS. ORIP CONSISTS OF THE DIVISION OF COMPARATIVE MEDICINE (DCM) AND THE DIVISION OF CONSTRUCTION AND INSTRUMENTS (DCI).
Place of Performance
Davis, California 95616 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 200% from $1,341,300 to $4,023,900.
Davis University Of California was awarded Somatic Cell Genome Editing in Primate Center Cooperative Agreement U42OD035737 worth $4,023,900 from the National Institute of Allergy and Infectious Diseases in September 2023 with work to be completed primarily in Davis California United States. The grant has a duration of 5 years and was awarded through assistance program 93.351 Research Infrastructure Programs. The Cooperative Agreement was awarded through grant opportunity Testing Centers for Development of Somatic Cell Genome Editing in Model Organisms (U42) (Clinical Trials Not Allowed).

Status
(Ongoing)

Last Modified 8/20/25

Period of Performance
9/1/23
Start Date
8/31/28
End Date
39.0% Complete

Funding Split
$4.0M
Federal Obligation
$0.0
Non-Federal Obligation
$4.0M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to U42OD035737

Transaction History

Modifications to U42OD035737

Additional Detail

Award ID FAIN
U42OD035737
SAI Number
U42OD035737-3312264390
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75AGNA NIH AGGREGATE FINANCIAL ASSISTANCE DATA AWARDING OFFICE
Funding Office
75NA00 NIH OFFICE OF THE DIRECTOR
Awardee UEI
TX2DAGQPENZ5
Awardee CAGE
1CBG4
Performance District
CA-04
Senators
Dianne Feinstein
Alejandro Padilla

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
Office of the Director, National Institutes of Health, Health and Human Services (075-0846) Health research and training Grants, subsidies, and contributions (41.0) $1,341,300 100%
Modified: 8/20/25