U24MD020517

THE PENN STATE COORDINATING CENTER (CC) FOR THE MULTI-SECTORAL PREVENTIVE INTERVENTIONS (MSPI) RESEARCH NETWORK - ABSTRACT A RESEARCH GAP EXISTS FOR PROJECTS FOCUSING ON THE LEADING RISK FACTORS FOR DEATH AND DISABILITY, ESPECIALLY WITHIN POPULATIONS AFFECTED BY HEALTH DISPARITIES. TO ADDRESS THIS GAP, THE OFFICE OF DISEASE PREVENTION (ODP), THE NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH DISPARITIES (NIMHD), AND THE OFFICE OF DATA SCIENCE STRATEGY (ODSS) AT THE NATIONAL INSTITUTES OF HEALTH ANNOUNCED THEIR INTENTION TO ESTABLISH THE MULTI-SECTORAL PREVENTIVE INTERVENTIONS (MSPI) RESEARCH NETWORK. THE ODP HAS INITIATED A NEW TRANS-NIH RESEARCH EFFORT, TITLED ADVANCE (ADVANCING PREVENTIVE INTERVENTION RESEARCH IN POPULATIONS THAT EXPERIENCE HEALTH DISPARITIES) INITIATIVE, OF WHICH THE MSPI RESEARCH NETWORK WILL BE A COMPONENT. THE MULTI-SECTORAL PREVENTIVE INTERVENTIONS (MSPI) RESEARCH NETWORK, INCLUDING THE COORDINATING CENTER (CC) AND UP TO 10 RESEARCH PROJECTS, WILL WORK COLLABORATIVELY WITH THE NIH TO TEST PREVENTIVE INTERVENTIONS ADDRESSING SOCIAL DETERMINANTS OF HEALTH (SDOH) AND RISK FACTORS FOR CHRONIC OR ACUTE HEALTH CONDITIONS, ESPECIALLY IN POPULATIONS THAT EXPERIENCE HEALTH DISPARITIES. THE PENNSYLVANIA STATE UNIVERSITY COLLEGE OF MEDICINE (PSUCOM) PROPOSES TO SERVE AS THE CC FOR THE MSPI RESEARCH NETWORK. THE CC WILL PROVIDE OVERARCHING SUPPORT AND GUIDANCE TO THE NETWORK THROUGH THREE SPECIFIC AIMS: 1) ADMINISTRATION, COORDINATION, AND COMMUNICATION 2) METHODOLOGY, DATA, AND ANALYTIC SUPPORT AND CONSULTATION 3) COMMUNITY AND OTHER COLLABORATOR ENGAGEMENT AND DISSEMINATION. OUR INVESTIGATIVE TEAM IS HIGHLY EXPERIENCED IN BIOSTATISTICS AND LEADING COORDINATING CENTERS, HEALTH DISPARITIES, PREVENTION RESEARCH, DIABETES, OBESITY, CANCER PREVENTION, IMPLEMENTATION AND TEAM SCIENCE, COMMUNITY ENGAGEMENT, FAMILY-LEVEL INTERVENTIONS, COMMUNITY-LEVEL INTERVENTIONS, AND OTHER EXPERTISE ACROSS THE NIMHD RESEARCH FRAMEWORK LEVELS AND DOMAINS OF INFLUENCE. THE INVESTIGATIVE TEAM WILL PROVIDE INNOVATIVE SUPPORT AND GUIDANCE TO THE NETWORK. THROUGHOUT ALL SPECIFIC AIMS, THE CC WILL FOCUS THE NETWORK’S EFFORTS AROUND COMMUNITY ENGAGEMENT AND TEAM SCIENCE BEST PRACTICES TO ENSURE COMMUNITY MEMBERS ARE FULL PARTNERS IN THE RESEARCH PROJECTS. THE CC WILL SCHEDULE AND DOCUMENT ALL NETWORK ACTIVITIES, ESTABLISH AND FACILITATE THE NETWORK STEERING COMMITTEE AND WORKING GROUPS, DEVELOP GOVERNING POLICIES, AND BUILD COMMUNICATION PLATFORMS AND PUBLIC AND PRIVATE WEBSITES TO SUPPORT COLLABORATION; ALL WHILE CONSIDERING EASE OF USE FOR COMMUNITY PARTNERS. TO ENSURE THE UTMOST DATA INTEGRITY, THE CC WILL PROVIDE METHODOLOGICAL AND STATISTICAL CONSULTATION TO THE RESEARCH PROJECTS, PROVIDE CONSULTATION ON SDOH MEASURES, ASSIST WITH COMPILATION OF PUBLICLY AVAILABLE DATA, SUPPORT DATA HARMONIZATION AND ARCHIVAL, AND PROVIDE ALL TECHNICAL ASSISTANCE NEEDED. THE CC WILL CREATE AND SUPPORT NETWORK-WIDE COMMUNITY ADVISORY BOARDS, LEAD INFORMATION SHARING SESSIONS AND DEVELOP TOOL KITS TO EXCHANGE BEST PRACTICES FOR ENGAGEMENT AND DISSEMINATION ACROSS ALL COMMUNITIES. FURTHER, WE WILL CREATE PUBLIC-FACING COMMUNICATION MATERIALS SUCH AS SOCIAL MEDIA POSTS, VIDEOS, NEWSLETTERS, AND LAY BRIEFS THAT WILL BOTH PROMOTE THE NETWORK AND SHARE KEY RESEARCH FINDINGS FOR TRANSLATION INTO THE COMMUNITY TO ADDRESS HEALTH DISPARITIES.

Pennsylvania State University

TO SUPPORT BASIC, CLINICAL, SOCIAL, AND BEHAVIORAL RESEARCH, PROMOTE RESEARCH INFRASTRUCTURE AND TRAINING, FOSTER EMERGING PROGRAMS, DISSEMINATE INFORMATION, AND REACH OUT TO MINORITY AND OTHER HEALTH DISPARITY COMMUNITIES. THE NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH DISPARITIES (NIMHD) HAS ESTABLISHED PROGRAMS TO PURSUE THESE GOALS: (1) THE CENTERS OF EXCELLENCE PROGRAM PROMOTES RESEARCH TO IMPROVE MINORITY HEALTH AND/OR REDUCE AND ELIMINATE HEALTH DISPARITIES, BUILDS RESEARCH CAPACITY FOR MINORITY HEALTH AND HEALTH DISPARITIES RESEARCH IN ACADEMIC INSTITUTIONS, ENCOURAGES PARTICIPATION OF HEALTH DISPARITY GROUPS AND COMMUNITIES IN BIOMEDICAL AND BEHAVIORAL RESEARCH AND PREVENTION AND INTERVENTION ACTIVITIES, AND BRINGS TOGETHER INVESTIGATORS FROM RELEVANT DISCIPLINES IN A MANNER THAT WILL ENHANCE AND EXTEND THE EFFECTIVENESS OF THEIR RESEARCH, (2) NIMHD RESEARCH ENDOWMENT PROGRAM BUILDS RESEARCH CAPACITY AND INFRASTRUCTURE AT ELIGIBLE NIMHD CENTERS OF EXCELLENCE OR ELIGIBLE SECTION 736 HEALTH PROFESSIONS SCHOOLS (42 U.S.C. 293) TO FACILITATE MINORITY HEALTH AND OTHER HEALTH DISPARITIES RESEARCH TO CLOSE THE DISPARITY GAP IN THE BURDEN OF ILLNESS AND DEATH EXPERIENCED BY RACIAL AND ETHNIC MINORITY AMERICANS AND OTHER HEALTH DISPARITY POPULATIONS, PROMOTES A DIVERSE AND STRONG SCIENTIFIC, TECHNOLOGICAL AND ENGINEERING WORKFORCE, AND EMPHASIZES THE RECRUITMENT AND RETENTION OF UNDERREPRESENTED MINORITIES AND OTHER SOCIO-ECONOMICALLY DISADVANTAGED POPULATIONS IN THE FIELDS OF BIOMEDICAL AND BEHAVIORAL RESEARCH AND OTHER AREAS OF THE SCIENTIFIC WORKFORCE, (3) THE CENTERS OF EXCELLENCE ON ENVIRONMENTAL HEALTH DISPARITIES RESEARCH TO STIMULATE BASIC AND APPLIED RESEARCH ON ENVIRONMENTAL HEALTH DISPARITIES, (4) MINORITY HEALTH AND HEALTH DISPARITIES INTERNATIONAL RESEARCH TRAINING PROGRAM (MHIRT) AWARDS ENABLE U.S. INSTITUTIONS TO TAILOR SHORT-TERM BASIC SCIENCE, BIOMEDICAL AND BEHAVIORAL MENTORED STUDENT INTERNATIONAL RESEARCH TRAINING OPPORTUNITIES TO ADDRESS GLOBAL ISSUES RELATED TO UNDERSTANDING, REDUCING, AND ELIMINATING HEALTH DISPARITIES, (5) SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM INCREASES PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT, ENCOURAGES SMALL BUSINESS PARTICIPATION IN FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTERS AND ENCOURAGES PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN TECHNOLOGICAL INNOVATION, (6) SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM STIMULATES AND FOSTERS SCIENTIFIC AND TECHNOLOGICAL INNOVATION THROUGH COOPERATIVE RESEARCH DEVELOPMENT CARRIED OUT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, FOSTERS TECHNOLOGY TRANSFER BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, INCREASES PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTERS AND ENCOURAGES PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN TECHNOLOGICAL INNOVATION, (7) HEALTH DISPARITIES RESEARCH PROJECT GRANTS (RPG) SUPPORT INNOVATIVE PROJECTS TO ENHANCE OUR UNDERSTANDING OF BIOLOGICAL MECHANISMS, SOCIAL, BEHAVIORAL, AND HEALTH SERVICES THAT CAN DIRECTLY AND DEMONSTRABLY CONTRIBUTE TO THE IMPROVEMENT IN MINORITY HEALTH AND THE ELIMINATION OF HEALTH DISPARITIES WHICH INCLUDES THE (8) RESEARCH CENTERS IN MINORITY INSTITUTIONS (RCMI) BUILD CAPACITY FOR BASIC BIOMEDICAL AND/OR BEHAVIORAL RESEARCH, CLINICAL AND TRANSLATIONAL RESEARCH (RCTR) AND A NETWORK (RCTN) BY FOCUSING ON INSTITUTIONAL RESOURCE DEVELOPMENT, SUCH AS SUPPORTING CORE RESEARCH FACILITIES AND STAFF, PURCHASING ADVANCED INSTRUMENTATION, AND LABORATORY RENOVATIONS/ALTERATIONS (9) CLINICAL RESEARCH EDUCATION AND CAREER DEVELOPMENT (CRECD) AWARDS PROVIDE DIDACTIC TRAINING AND MENTORED CLINICAL RESEARCH EXPERIENCES TO DEVELOP INDEPENDENT RESEARCHERS WHO CAN LEAD CLINICAL RESEARCH STUDIES, ESPECIALLY THOSE ADDRESSING HEALTH DISPARITIES, (10) PATHWAY TO INDEPENDENCE AWARDS (K99/R00) TO INCREASE AND MAINTAIN A STRONG COHORT OF NEW AND TALENTED, NIH-SUPPORTED, INDEPENDENT INVESTIGATORS. (11) NIH RESEARCH CONFERENCE GRANT AND NIH RESEARCH CONFERENCE COOPERATIVE AGREEMENT PROGRAMS SUPPORT HIGH-QUALITY CONFERENCES THAT ARE RELEVANT TO THE MINORITY HEALTH AND HEALTH DISPARITIES, (12) TRANSDISCIPLINARY COLLABORATIVE CENTERS FOR HEALTH DISPARITIES RESEARCH COMPRISE REGIONAL COALITIONS OF ACADEMIC INSTITUTIONS, COMMUNITY ORGANIZATIONS, SERVICE PROVIDERS AND SYSTEMS, GOVERNMENT AGENCIES AND OTHER STAKEHOLDERS CONDUCTING COORDINATED RESEARCH, IMPLEMENTATION AND DISSEMINATION ACTIVITIES THAT TRANSCEND CUSTOMARY APPROACHES AND SILO ORGANIZATIONAL STRUCTURES TO ADDRESS CRITICAL QUESTIONS AT MULTIPLE LEVELS IN INNOVATIVE WAYS FOCUSED ON PRIORITY RESEARCH AREAS IN MINORITY HEALTH AND HEALTH DISPARITIES, (13) RUTH L. KIRSCHSTEIN NRSA INDIVIDUAL PREDOCTORAL FELLOWSHIP

93.310 - Trans-NIH Research Support

National Institute for Minority Health and Health Disparities (NIMHD) [HHS - NIH]

National Institute of Allergy and Infectious Diseases (NIAID) [HHS - NIH]

Pennsylvania United States

State-Wide

Coordinating Center to Support Multi-Sectoral Preventive Interventions that Address Social Determinants of Health in Populations that Experience Health Disparities (U24, Clinical Trial Not Allowed) (RFA-OD-24-006)

Amendment Since initial award the total obligations have increased 100% from $1,662,575 to $3,325,772.