U24HD113146

Achieving Maternal Equity and Transforming Health Through Implementation Science and Training (AMETHIST@PENN) - Project Summary (Abstract)

Achieving Maternal Equity and Transforming Health Through Implementation Science and Training (AMETHIST@PENN) The NIH Implementing a Maternal Health and Pregnancy Outcomes Vision for Everyone (IMPROVE) initiative aims to reduce maternal mortality, improve pregnancy, perinatal and postpartum care, and to address the factors that have led to severe disparities in outcomes for marginalized groups.

The University of Pennsylvania (Penn) proposes creating the Achieving Maternal Equity and Transforming Health Through Implementation Science and Training (AMETHIST@PENN) Implementation Science Hub to support IMPROVE Maternal Health Research Centers of Excellence (COEs) and other IMPROVE investigators, and to coordinate with NIH staff scientists, project staff, and the Data Innovation and Coordinating Hub.

AMETHIST@PENN will be led by MPIs Meghan Lane Fall, MD, MSHP, and Rebecca Hamm, MD, MSCE, who bring complementary and necessary strengths in Implementation Science (IS) and Maternal Health. Dr. Lane-Fall is Executive Director of the Penn Implementation Science Center at the Leonard Davis Institute of Health Economics (PISCE@LDI). She is an internationally recognized acute care IS expert with an independent IS research program. She has 8 years of experience as a collaborator and consultant advising investigators on: selection of IS theories, models, and frameworks, including those focused on equity; implementation mapping and strategy selection; implementation outcome selection; data integration across multiple types and sources; and advanced analytic procedures to elucidate change mechanisms.

Dr. Hamm is a Maternal Fetal Medicine specialist who has established herself nationally as a researcher at the crossroads of obstetrics and IS. Together they will orchestrate the work of AMETHIST@PENN, leading an interdisciplinary, interprofessional group of more than 45 scientists and community partners. The AMETHIST@PENN Hub will comprise five cores, each with two co-leads and 2-4 core investigators: 1) Administration, Leadership, and Evaluation; 2) Equity, Community and Stakeholder Engagement (with an Equity Advisory and Oversight Board to advise and hold investigators accountable for incorporating equity into their research); 3) Design, Methods, and Analysis (including a consultant panel with methods, equity, and clinical subpanels to meet the anticipated consultation and technical assistance needs of the COEs); 4) Policy, Dissemination, and Communication (with skills building in messaging and media training); and 5) Training and Capacity Building (featuring an innovative academic-community partner training program and a comprehensive mentored research experience for both new and established investigators).

In addition to establishing and administering the Hub, a research aim includes prospective mixed methods research on IS investigators, community partners, and institutions to characterize predictors of project-based implementation success and multilevel barriers to and facilitators of the conduct of maternal health IS research. The AMETHIST@PENN Hub will advance public health and maternal health equity by facilitating rigorous implementation research that centers the needs and perspectives of patients, communities, and health disparity populations.

Trustees Of The University Of Pennsylvania

TO CONDUCT AND SUPPORT LABORATORY RESEARCH, CLINICAL TRIALS, AND STUDIES WITH PEOPLE THAT EXPLORE HEALTH PROCESSES. NICHD RESEARCHERS EXAMINE GROWTH AND DEVELOPMENT, BIOLOGIC AND REPRODUCTIVE FUNCTIONS, BEHAVIOR PATTERNS, AND POPULATION DYNAMICS TO PROTECT AND MAINTAIN THE HEALTH OF ALL PEOPLE. TO EXAMINE THE IMPACT OF DISABILITIES, DISEASES, AND DEFECTS ON THE LIVES OF INDIVIDUALS. WITH THIS INFORMATION, THE NICHD HOPES TO RESTORE, INCREASE, AND MAXIMIZE THE CAPABILITIES OF PEOPLE AFFECTED BY DISEASE AND INJURY. TO SPONSOR TRAINING PROGRAMS FOR SCIENTISTS, DOCTORS, AND RESEARCHERS TO ENSURE THAT NICHD RESEARCH CAN CONTINUE. BY TRAINING THESE PROFESSIONALS IN THE LATEST RESEARCH METHODS AND TECHNOLOGIES, THE NICHD WILL BE ABLE TO CONDUCT ITS RESEARCH AND MAKE HEALTH RESEARCH PROGRESS UNTIL ALL CHILDREN, ADULTS, FAMILIES, AND POPULATIONS ENJOY GOOD HEALTH. THE MISSION OF THE NICHD IS TO ENSURE THAT EVERY PERSON IS BORN HEALTHY AND WANTED, THAT WOMEN SUFFER NO HARMFUL EFFECTS FROM REPRODUCTIVE PROCESSES, AND THAT ALL CHILDREN HAVE THE CHANCE TO ACHIEVE THEIR FULL POTENTIAL FOR HEALTHY AND PRODUCTIVE LIVES, FREE FROM DISEASE OR DISABILITY, AND TO ENSURE THE HEALTH, PRODUCTIVITY, INDEPENDENCE, AND WELL-BEING OF ALL PEOPLE THROUGH OPTIMAL REHABILITATION.

93.865 - Child Health and Human Development Extramural Research

National Institute of Child Health and Human Development (NICHD) [HHS - NIH]

Philadelphia, Pennsylvania 191044865 United States

Single Zip Code

Maternal Health Research Centers of Excellence Implementation Science Hub/Resource Center (U24 Clinical Trial Optional) (RFA-HD-23-037)

Amendment Since initial award the total obligations have increased 214% from $2,749,745 to $8,629,719.