U24CA268228

Traditional and New Dietary Assessment Methods (TANDAM) for Personalized Nutrition - Project Summary/Abstract

Errors in dietary assessment methods attenuate the association between diet and chronic disease outcomes, such as obesity and cancer, which derails efforts to aggressively pursue policies directed to improving dietary intakes in the population.

Harnessing the capabilities of mobile-based and image-based technology tools offer an opportunity to reach a wide audience via cost-effective, convenient, timely, and familiar channels. Properly constructed and validated, these tools would eliminate the labor-intensive coding required for traditional paper and interview methods.

Successfully creating tools which tap into several specialty areas of science and behavior requires a multidisciplinary team of scientists. For several, the research group represented in the proposal have been committed to advancing dietary assessment methods. We have made progress with harnessing the availability of the ubiquitous and popular mobile telephone, passive methods, and the automated self-administered 24-hour dietary assessment (ASA24).

Our research group represents a partnership between nutrition scientists/epidemiologists, engineers specializing in image analysis, registered dietitians, and biostatisticians. Having completed multiple studies demonstrating the efficacy of the technology-assisted dietary assessment (TADA) system through the use of the mobile food record (MFR) app, we recognize the value of having multiple validated tools available to better accommodate diverse research questions, variations due to age or levels of cognition.

The Nutrition for Precision Health powered by the All of Us Research Program provides a unique opportunity to test multiple methods of dietary assessment using modern and novel methods. To fully take advantage of this opportunity, we will deploy ASA24 web-based tool; the MFR, an image-based app; and a passive method, the Automatic Ingestion Monitor V2 (AIM-2). Further, we will combine methods and include the ASA24 as a dietary record and the ASA24 combined with the MFR.

Advancing technology tools would facilitate precision dietary assessment and research translation to better comprehend eating behaviors, define diet-disease relationships, and assess the effectiveness of intervention programs.

University Of Hawaii

TO IDENTIFY CANCER RISKS AND RISK REDUCTION STRATEGIES, TO IDENTIFY FACTORS THAT CAUSE CANCER IN HUMANS, AND TO DISCOVER AND DEVELOP MECHANISMS FOR CANCER PREVENTION AND PREVENTIVE INTERVENTIONS IN HUMANS. RESEARCH PROGRAMS INCLUDE: (1) CHEMICAL, PHYSICAL AND MOLECULAR CARCINOGENESIS, (2) SCREENING, EARLY DETECTION AND RISK ASSESSMENT, INCLUDING BIOMARKER DISCOVERY, DEVELOPMENT AND VALIDATION, (3) EPIDEMIOLOGY, (4) NUTRITION AND BIOACTIVE FOOD COMPONENTS, (5) IMMUNOLOGY AND VACCINES, (6) FIELD STUDIES AND STATISTICS, (7) CANCER CHEMOPREVENTION AND INTERCEPTION, (8) PRE-CLINICAL AND CLINICAL AGENT DEVELOPMENT, (9) ORGAN SITE STUDIES AND CLINICAL TRIALS, (10) HEALTH-RELATED QUALITY OF LIFE AND PATIENT-CENTERED OUTCOMES, AND (11) SUPPORTIVE CARE AND MANAGEMENT OF SYMPTOMS AND TOXICITIES. SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM: TO EXPAND AND IMPROVE THE SBIR PROGRAM, TO STIMULATE TECHNICAL INNOVATION, TO INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT FUNDING, TO INCREASE SMALL BUSINESS PARTICIPATION IN FEDERAL RESEARCH AND DEVELOPMENT, AND TO FOSTER AND ENCOURAGE PARTICIPATION IN INNOVATION AND ENTREPRENEURSHIP BY WOMEN AND SOCIALLY/ECONOMICALLY DISADVANTAGED PERSONS. SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM: TO STIMULATE AND FOSTER SCIENTIFIC AND TECHNOLOGICAL INNOVATION THROUGH COOPERATIVE RESEARCH AND DEVELOPMENT CARRIED OUT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, TO FOSTER TECHNOLOGY TRANSFER THROUGH COOPERATIVE RESEARCH AND DEVELOPMENT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, TO INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT FUNDING, AND FOSTER PARTICIPATION IN INNOVATION AND ENTREPRENEURSHIP BY WOMEN AND SOCIALLY/ECONOMICALLY DISADVANTAGED PERSONS.

93.310 - Trans-NIH Research Support

National Cancer Institute (NCI) [HHS - NIH]

National Institute of Allergy and Infectious Diseases (NIAID) [HHS - NIH]

Hawaii United States

State-Wide

Nutrition for Precision Health, powered by the All of Us Research Program: Dietary Assessment Center (U24 Clinical Trial Optional) (RFA-RM-21-004)

Amendment Since initial award the total obligations have increased 375% from $1,410,520 to $6,695,285.