U19CA291431

The Mass Partnership for Community-Engaged Cancer Control Equity - Abstract

The Massachusetts Partnership for Community-Engaged Cancer Control Equity (MASS PCECCE) builds on a robust partnership between the Harvard T.H. Chan School of Public Health, the Massachusetts League of Community Health Centers, and Mass General Brigham.

The proposed center is well-poised to further accelerate community-academic collaborations to advance transformative solutions for cancer equity.

Our center's theme is advancing cancer control equity by strengthening Community Health Center's (CHC) capacity to deliver evidence-based cancer screening and tobacco treatment and by promoting social and digital connection among patients and their communities.

Advancing cancer control equity will result from CHC systems that deliver evidence-based care together with community organizations that support community needs.

The partnership has selected four local priorities as SDOH targets: (1) social capital, which reflect the resources embedded within social connections; (2) civic engagement, or the actions that a community takes to improve its circumstances; (3) access to digital skills and technology (here forward referred to as “digital access”), which impacts on equity in access to health care and social resources that support health; and (4) access to evidence-based cancer control care for breast, cervical, and colorectal cancer screening and tobacco treatment, reflecting Healthy People 2030 objectives.

We will conduct a multi-level intervention at 2 levels— the community level to build community social capital and civic participation, enabling engagement that will improve resident access to health and economic resources, and the systems level to improve cancer control care (e.g. cancer screening and tobacco treatment) and digital access, by digital needs screening and navigation to needed resources.

To support the center's goals and planned research, we will: (1) create a community-partnered approach to conducting research and building both community and CHC capacity to address key SDOH through a strong admin core; (2) create a process for developing and sustaining research that is responsive to community interests through our Community Responsive Project (CRP) program; and (3) create an innovative, centralized approach for efficient collection, management, and sharing of research data across the center through a data ecosystem, and supporting the methodologic needs of the center through a research methods, measurement, and data management core.

This is a highly integrated center with a strong emphasis on capacity building for all partners.

We aim to link CHCs and communities in ways that maximize civic engagement and participation in cancer control research and care to address health inequities, using approaches that are scalable and sustainable across MA and nationally.

President And Fellows Of Harvard College

TO IDENTIFY CANCER RISKS AND RISK REDUCTION STRATEGIES, TO IDENTIFY FACTORS THAT CAUSE CANCER IN HUMANS, AND TO DISCOVER AND DEVELOP MECHANISMS FOR CANCER PREVENTION AND PREVENTIVE INTERVENTIONS IN HUMANS. RESEARCH PROGRAMS INCLUDE: (1) CHEMICAL, PHYSICAL AND MOLECULAR CARCINOGENESIS, (2) SCREENING, EARLY DETECTION AND RISK ASSESSMENT, INCLUDING BIOMARKER DISCOVERY, DEVELOPMENT AND VALIDATION, (3) EPIDEMIOLOGY, (4) NUTRITION AND BIOACTIVE FOOD COMPONENTS, (5) IMMUNOLOGY AND VACCINES, (6) FIELD STUDIES AND STATISTICS, (7) CANCER CHEMOPREVENTION AND INTERCEPTION, (8) PRE-CLINICAL AND CLINICAL AGENT DEVELOPMENT, (9) ORGAN SITE STUDIES AND CLINICAL TRIALS, (10) HEALTH-RELATED QUALITY OF LIFE AND PATIENT-CENTERED OUTCOMES, AND (11) SUPPORTIVE CARE AND MANAGEMENT OF SYMPTOMS AND TOXICITIES. SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM: TO EXPAND AND IMPROVE THE SBIR PROGRAM, TO STIMULATE TECHNICAL INNOVATION, TO INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT FUNDING, TO INCREASE SMALL BUSINESS PARTICIPATION IN FEDERAL RESEARCH AND DEVELOPMENT, AND TO FOSTER AND ENCOURAGE PARTICIPATION IN INNOVATION AND ENTREPRENEURSHIP BY WOMEN AND SOCIALLY/ECONOMICALLY DISADVANTAGED PERSONS. SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM: TO STIMULATE AND FOSTER SCIENTIFIC AND TECHNOLOGICAL INNOVATION THROUGH COOPERATIVE RESEARCH AND DEVELOPMENT CARRIED OUT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, TO FOSTER TECHNOLOGY TRANSFER THROUGH COOPERATIVE RESEARCH AND DEVELOPMENT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, TO INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT FUNDING, AND FOSTER PARTICIPATION IN INNOVATION AND ENTREPRENEURSHIP BY WOMEN AND SOCIALLY/ECONOMICALLY DISADVANTAGED PERSONS.

93.393 - Cancer Cause and Prevention Research

National Cancer Institute (NCI) [HHS - NIH]

Boston, Massachusetts 021156028 United States

Single Zip Code

Advancing Cancer Control Equity Research Through Transformative Solutions (U19 Clinical Trial Optional) (RFA-CA-23-026)

Amendment Since initial award the total obligations have increased 96% from $1,971,041 to $3,857,723.