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T32GM152349

Project Grant

Overview

Grant Description
Weill Cornell/Rockefeller/Sloan Kettering MST Program - Project Summary
The mission of the Tri-Institutional MD-PhD Program (Tri-I) is to train a diverse and empowered group of clinician-scientists prepared to bridge the gap between laboratory research and clinical medicine.
Graduates of the program are well-grounded in human biology, pathophysiology, and clinical medicine and are endowed with an advanced understanding of biomedical science, as well as a mastery of critical thinking and experimental skills.

These skills will allow them to undertake complex, interdisciplinary, quantitative, and collaborative studies to elucidate basic biological processes pertaining to human health and disease and to transfer advances in research to the understanding, prevention, and treatment of human disease.
Tri-I is a joint undertaking between Weill Cornell Medicine (WCM), The Rockefeller University (RU), and Memorial Sloan Kettering Cancer Center (MSK).
Trainees complete their MD degree at Weill Cornell Medical College (WCMC), and PhD training at one of the three participating graduate schools: Weill Cornell Graduate School of Medical Sciences (WCGS); The David Rockefeller Graduate Program in Bioscience at RU; or The Louis V. Gerstner Jr. Graduate School of Biomedical Sciences (GSK) at MSK.

An integrated curriculum reinforces the students’ identities as clinician-scientists.
In the first two years in the program, MD-PhD-specific graduate-level coursework, including training in quantitative methods, responsible conduct of research, and rigor and reproducibility, is integrated with pre-clinical medical school courses and 18 weeks of core clinical clerkships.
Students complete three laboratory research rotations in at least two different institutions before selecting a thesis lab and enrolling in the graduate school at which their thesis mentor has their primary appointment.

PhD requirements are comparable for all MD-PhD students across graduate institutions, and trainees may take courses for credit in any of the graduate schools.
After they have defended their thesis, trainees complete their remaining clinical training at WCMC.
Over 200 participating faculty members serve as mentors and undergo training to ensure a safe training environment, responsible conduct of research, and scientific rigor and reproducibility.

Students receive multi-layered mentorship and advising, particularly around transitions to and from the laboratory and in preparation for post-graduate residency training.
Based on Tri-I’s high trainee retention in the program and in academia and biomedical research following graduation, this application requests funds to support 49 trainees per year.
No trainee will be appointed to the grant for more than a total of four years.

The student body averages 150 MD-PhD trainees; currently, 47% identify as women and 23% come from racial and ethnic backgrounds underrepresented in medicine and science.
Over the past 50 years, 451 MD-PhDs have graduated from Tri-I and its predecessors.
In the past 15 years, 85% of graduates have appointments in medical schools, research institutes, or biotech/pharma.

Tri-I is committed to maintaining its longstanding tradition of training future leaders of biomedical research.
Funding Goals
THE NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES (NIGMS) SUPPORTS BASIC RESEARCH THAT INCREASES OUR UNDERSTANDING OF BIOLOGICAL PROCESSES AND LAYS THE FOUNDATION FOR ADVANCES IN DISEASE DIAGNOSIS, TREATMENT, AND PREVENTION. NIGMS ALSO SUPPORTS RESEARCH IN SPECIFIC CLINICAL AREAS THAT AFFECT MULTIPLE ORGAN SYSTEMS: ANESTHESIOLOGY AND PERI-OPERATIVE PAIN, CLINICAL PHARMACOLOGY ?COMMON TO MULTIPLE DRUGS AND TREATMENTS, AND INJURY, CRITICAL ILLNESS, SEPSIS, AND WOUND HEALING.? NIGMS-FUNDED SCIENTISTS INVESTIGATE HOW LIVING SYSTEMS WORK AT A RANGE OF LEVELSFROM MOLECULES AND CELLS TO TISSUES AND ORGANSIN RESEARCH ORGANISMS, HUMANS, AND POPULATIONS. ADDITIONALLY, TO ENSURE THE VITALITY AND CONTINUED PRODUCTIVITY OF THE RESEARCH ENTERPRISE, NIGMS PROVIDES LEADERSHIP IN SUPPORTING THE TRAINING OF THE NEXT GENERATION OF SCIENTISTS, ENHANCING THE DIVERSITY OF THE SCIENTIFIC WORKFORCE, AND DEVELOPING RESEARCH CAPACITY THROUGHOUT THE COUNTRY.
Place of Performance
New York United States
Geographic Scope
State-Wide
Analysis Notes
Amendment Since initial award the total obligations have increased 81% from $2,517,309 to $4,558,385.
Weill Medical College Of Cornell University was awarded Tri-I MD-PhD Program: Bridging Research & Medicine Project Grant T32GM152349 worth $4,558,385 from the National Institute of General Medical Sciences in July 2024 with work to be completed primarily in New York United States. The grant has a duration of 5 years and was awarded through assistance program 93.859 Biomedical Research and Research Training. The Project Grant was awarded through grant opportunity Medical Scientist Training Program (T32).

Status
(Ongoing)

Last Modified 7/25/25

Period of Performance
7/1/24
Start Date
6/30/29
End Date
22.0% Complete

Funding Split
$4.6M
Federal Obligation
$0.0
Non-Federal Obligation
$4.6M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to T32GM152349

Transaction History

Modifications to T32GM152349

Additional Detail

Award ID FAIN
T32GM152349
SAI Number
T32GM152349-3416069334
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NS00 NIH National Institute of General Medical Sciences
Funding Office
75NS00 NIH National Institute of General Medical Sciences
Awardee UEI
YNT8TCJH8FQ8
Awardee CAGE
1UMU6
Performance District
NY-90
Senators
Kirsten Gillibrand
Charles Schumer
Modified: 7/25/25