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T32GM152284

Project Grant

Overview

Grant Description
Medical Scientist Training Program - This proposal requests support for the Medical Scientist Training Program (MSTP) at the Vanderbilt University School of Medicine. The program's primary goal is to identify, recruit, train, and mentor a diverse workforce of compassionate and dedicated future physician-scientists.

These Vanderbilt-trained physician-scientists will serve critical needs in all aspects of medicine, science, industry, and government to improve human health, reduce disparities, and improve society through leadership in biomedical research and clinical practice. Our joint MD-PhD program is based on rigorous training in clinical medicine and scientific inquiry.

Core program elements explicitly developed for dual-degree students include a foundational biomedical course, a literature-based seminar series, the clinical preceptorship program, seminar series, leadership workshops, the physician-scientist speaker series, extensive near-peer mentoring, a host of student-led institutional and community outreach activities to give back to the community, and an annual retreat to reinforce connections, hear about great science, and learn together.

Students receive formal instruction in quantitative reasoning, responsible conduct of research, and rigor and reproducibility threaded and reinforced throughout the curriculum. An innovative advising college program offers opportunities for vertical integration of faculty members and both physician-scientists in residency and MSTP trainees.

Current students play key roles in student recruitment and curriculum development. Our alumni are exceptionally accomplished which include the founding president of the Gladstone Institute, three deans, three department chairs, 26 full professors, and 18 industry leaders. More recent graduates still in training are in superb residencies and fellowships.

The 109 current trainees come from 74 colleges and universities distributed across North America. The growth of our nationwide applicant pool results from concerted recruiting efforts, including those focused on recruiting students from underrepresented groups in medicine. In the current year, 595 applications have been received, from which 15 students will be selected to enter the incoming class.

The educational environment for physician-scientists at Vanderbilt University ranked #12 in NIH funding, is outstanding and built on established strengths in biomedical informatics, cancer biology, cell biology, clinical pharmacology, diabetes, neurosciences, toxicology, drug discovery, genetics, chemical and physical biology, imaging sciences, microbial pathogenesis, pharmacogenomics, and vaccine science.

Newer areas of research emphasize immunobiology, inflammation and cancer, precision medicine, quantitative systems biology, and structural biology. Based on the commitment of our leadership team, the strength of our applicant pool, enhanced opportunities for physician-scientist training, a longstanding institutional commitment to the education of MSTP leaders in biomedical research, and the success of our graduates in academic medicine, this proposal requests an increase in positions to 27 for the five-year project period.
Funding Goals
THE NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES (NIGMS) SUPPORTS BASIC RESEARCH THAT INCREASES OUR UNDERSTANDING OF BIOLOGICAL PROCESSES AND LAYS THE FOUNDATION FOR ADVANCES IN DISEASE DIAGNOSIS, TREATMENT, AND PREVENTION. NIGMS ALSO SUPPORTS RESEARCH IN SPECIFIC CLINICAL AREAS THAT AFFECT MULTIPLE ORGAN SYSTEMS: ANESTHESIOLOGY AND PERI-OPERATIVE PAIN, CLINICAL PHARMACOLOGY ?COMMON TO MULTIPLE DRUGS AND TREATMENTS, AND INJURY, CRITICAL ILLNESS, SEPSIS, AND WOUND HEALING.? NIGMS-FUNDED SCIENTISTS INVESTIGATE HOW LIVING SYSTEMS WORK AT A RANGE OF LEVELSFROM MOLECULES AND CELLS TO TISSUES AND ORGANSIN RESEARCH ORGANISMS, HUMANS, AND POPULATIONS. ADDITIONALLY, TO ENSURE THE VITALITY AND CONTINUED PRODUCTIVITY OF THE RESEARCH ENTERPRISE, NIGMS PROVIDES LEADERSHIP IN SUPPORTING THE TRAINING OF THE NEXT GENERATION OF SCIENTISTS, ENHANCING THE DIVERSITY OF THE SCIENTIFIC WORKFORCE, AND DEVELOPING RESEARCH CAPACITY THROUGHOUT THE COUNTRY.
Place of Performance
Nashville, Tennessee 37203 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 97% from $1,618,270 to $3,192,986.
Vanderbilt University was awarded Vanderbilt MSTP: Training Future Physician-Scientists Project Grant T32GM152284 worth $3,192,986 from the National Institute of General Medical Sciences in July 2024 with work to be completed primarily in Nashville Tennessee United States. The grant has a duration of 5 years and was awarded through assistance program 93.859 Biomedical Research and Research Training. The Project Grant was awarded through grant opportunity Medical Scientist Training Program (T32).

Status
(Ongoing)

Last Modified 8/20/25

Period of Performance
7/1/24
Start Date
6/30/29
End Date
23.0% Complete

Funding Split
$3.2M
Federal Obligation
$0.0
Non-Federal Obligation
$3.2M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to T32GM152284

Transaction History

Modifications to T32GM152284

Additional Detail

Award ID FAIN
T32GM152284
SAI Number
T32GM152284-306445925
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NS00 NIH National Institute of General Medical Sciences
Funding Office
75NS00 NIH National Institute of General Medical Sciences
Awardee UEI
GTNBNWXJ12D5
Awardee CAGE
5E694
Performance District
TN-05
Senators
Marsha Blackburn
Bill Hagerty
Modified: 8/20/25