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T32GM144300

Project Grant

Overview

Grant Description
Medical Scientist Training Program - Our University of Pittsburgh-Carnegie Mellon University MSTP prepares MD-PhD trainees with the expertise and versatility to have highly productive careers as physician scientists and leaders in an evolving scientific and medical environment.

Students in our bi-institutional MSTP benefit from a world-class research and clinical community and a core group of 158 well-funded mentors in 22 affiliated graduate programs. Previous MSTP trainees have thrived in these programs, achieving a 62% F30 success rate and a median of six publications over the last five years. Currently, our MSTP has 94 trainees, with 55% of them being women and 15% from underrepresented backgrounds.

Unique features of the MSTP include a required core curriculum of seven courses beyond medical and graduate school coursework. These courses build specific research, translational, and professional competencies that are essential for durable success as physician scientists. Training in rigor and reproducibility, responsible conduct of research, and health equity are integrated throughout the curriculum and research and clinical training experiences. Our faculty members are also trained in these areas and engage in case-based workshops to learn and share best practices in mentoring MSTP trainees.

Additional features of our program include one-on-one executive coaching sessions for students, each student's personal career advisor who serves as an advocate, guide, and IDP reviewer from matriculation to graduation and beyond, and the programmatic and intellectual integration of clinical and research training.

The objectives of our program include:
1. Imparting transformational knowledge and thinking skills: We aim to build students' ability to frame testable hypotheses addressing significant research questions that can be linked to clinical knowledge. We also prepare trainees to plan, conduct, analyze, and publish significant, rigorous, high-quality, reproducible research and obtain funding to support it.
2. Expanding trainees' toolkit: We position trainees to meet evolving challenges in health and disease, as well as the demands on the physician scientist workforce. We prepare them for critical appraisal and use of new technologies and informatics.
3. Building skills for forging productive partnerships: We train students to develop and refine ideas while engaging stakeholders. We also aim to equip them with the ability to work effectively in teams, communicate and learn from diverse audiences, and convey the joy of discovery.

In addition to measuring deliverables and career milestones as outcomes, we will also test the ability of the program to build student confidence in research self-efficacy and professional self-efficacy. We engage expert input for learning assessment and strategic planning to ensure that our MSTP remains dynamic, inclusive, and adaptable to the scientific landscape.
Funding Goals
THE NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES (NIGMS) SUPPORTS BASIC RESEARCH THAT INCREASES OUR UNDERSTANDING OF BIOLOGICAL PROCESSES AND LAYS THE FOUNDATION FOR ADVANCES IN DISEASE DIAGNOSIS, TREATMENT, AND PREVENTION. NIGMS ALSO SUPPORTS RESEARCH IN SPECIFIC CLINICAL AREAS THAT AFFECT MULTIPLE ORGAN SYSTEMS: ANESTHESIOLOGY AND PERI-OPERATIVE PAIN, CLINICAL PHARMACOLOGY ?COMMON TO MULTIPLE DRUGS AND TREATMENTS, AND INJURY, CRITICAL ILLNESS, SEPSIS, AND WOUND HEALING.? NIGMS-FUNDED SCIENTISTS INVESTIGATE HOW LIVING SYSTEMS WORK AT A RANGE OF LEVELSFROM MOLECULES AND CELLS TO TISSUES AND ORGANSIN RESEARCH ORGANISMS, HUMANS, AND POPULATIONS. ADDITIONALLY, TO ENSURE THE VITALITY AND CONTINUED PRODUCTIVITY OF THE RESEARCH ENTERPRISE, NIGMS PROVIDES LEADERSHIP IN SUPPORTING THE TRAINING OF THE NEXT GENERATION OF SCIENTISTS, ENHANCING THE DIVERSITY OF THE SCIENTIFIC WORKFORCE, AND DEVELOPING RESEARCH CAPACITY THROUGHOUT THE COUNTRY.
Place of Performance
Pennsylvania United States
Geographic Scope
State-Wide
Analysis Notes
Amendment Since initial award the total obligations have increased 345% from $1,482,940 to $6,596,932.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education was awarded Pitt-CMU MSTP: Transforming MD-PhD Trainees Project Grant T32GM144300 worth $6,596,932 from the National Institute of General Medical Sciences in July 2022 with work to be completed primarily in Pennsylvania United States. The grant has a duration of 5 years and was awarded through assistance program 93.859 Biomedical Research and Research Training. The Project Grant was awarded through grant opportunity Medical Scientist Training Program (T32).

Status
(Ongoing)

Last Modified 7/3/25

Period of Performance
7/1/22
Start Date
6/30/27
End Date
63.0% Complete

Funding Split
$6.6M
Federal Obligation
$0.0
Non-Federal Obligation
$6.6M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to T32GM144300

Transaction History

Modifications to T32GM144300

Additional Detail

Award ID FAIN
T32GM144300
SAI Number
T32GM144300-3662739703
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Other
Awarding Office
75NS00 NIH National Institute of General Medical Sciences
Funding Office
75NS00 NIH National Institute of General Medical Sciences
Awardee UEI
MKAGLD59JRL1
Awardee CAGE
1DQV3
Performance District
PA-90
Senators
Robert Casey
John Fetterman

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute of General Medical Sciences, National Institutes of Health, Health and Human Services (075-0851) Health research and training Grants, subsidies, and contributions (41.0) $3,108,439 100%
Modified: 7/3/25