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T32GM141804

Project Grant

Overview

Grant Description
Cellular and Molecular Biology - The Cell, Molecular, Developmental Biology and Biophysics (CMDB) graduate program is an independent, stand-alone biomedical training program at Johns Hopkins University (JHU) that spans five basic science departments and the Carnegie Institution, all on the Arts and Sciences Homewood campus. It has been funded by a single T32 grant currently completing its 46th year.

The program seeks to produce independent biomedical scientists through rigorous training and wide-ranging experiences wherein they acquire robust, transferable skills in quantitative biology, science communication, teaching, mentoring, and community outreach. The CMDB training philosophy features two core components.

The first is a commitment to a broad but integrated training experience. Our interdisciplinary training faculty embody a breadth of research interests that span quantitative biophysics and biochemistry, developmental genetics, and modern cellular and molecular biology. Recent faculty hires introduced new areas of computational biology and genomics, further bolstering cross-disciplinary interactions, yet we remain a cohesive community, integrated via shared courses, seminars, and collaborations.

Students gain broad scientific, technical skills in all disciplines through a core curriculum and four rotations before specializing in their thesis research. Instruction and promotion of responsible research conduct is integral to the entire training.

The philosophy's second component represents forming a complete scientist. This involves more than excellence in the laboratory: we train researchers to be effective communicators, educators, and leaders and support their outreach efforts. To that end, we expanded our training to include development of scientific communication and teaching skills, and our students participate in scientific outreach locally and nationally. Via in-program initiatives and JHU resources, our students explore careers extending beyond academic research.

Recruitment efforts have led to one of the most diverse JHU graduate programs. On average, 17 TGE students matriculate into CMDB, and they will be supported by the T32 for their 1st year with stipend and tuition supplements provided by JHU.

In 2017, we launched a survey-based initiative to assess the program's effectiveness. The CMDB portal contains these data, providing transparent information to current and prospective students. This information guides the program - we foster innovation through data-driven decisions on faculty mentor training, student assessment, flexible career opportunities, and student retention.

This application details the program's gains and our plans to move forward with a philosophy that has already produced great success - dedication to broad, interdisciplinary scientific training, an emphasis on forming scientists who are outstanding communicators and educators and who give back to their communities, and a mission to recruit, nurture, and promote excellence in the next generation of biomedical researchers.
Funding Goals
THE NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES (NIGMS) SUPPORTS BASIC RESEARCH THAT INCREASES OUR UNDERSTANDING OF BIOLOGICAL PROCESSES AND LAYS THE FOUNDATION FOR ADVANCES IN DISEASE DIAGNOSIS, TREATMENT, AND PREVENTION. NIGMS ALSO SUPPORTS RESEARCH IN SPECIFIC CLINICAL AREAS THAT AFFECT MULTIPLE ORGAN SYSTEMS: ANESTHESIOLOGY AND PERI-OPERATIVE PAIN, CLINICAL PHARMACOLOGY ?COMMON TO MULTIPLE DRUGS AND TREATMENTS, AND INJURY, CRITICAL ILLNESS, SEPSIS, AND WOUND HEALING.? NIGMS-FUNDED SCIENTISTS INVESTIGATE HOW LIVING SYSTEMS WORK AT A RANGE OF LEVELSFROM MOLECULES AND CELLS TO TISSUES AND ORGANSIN RESEARCH ORGANISMS, HUMANS, AND POPULATIONS. ADDITIONALLY, TO ENSURE THE VITALITY AND CONTINUED PRODUCTIVITY OF THE RESEARCH ENTERPRISE, NIGMS PROVIDES LEADERSHIP IN SUPPORTING THE TRAINING OF THE NEXT GENERATION OF SCIENTISTS, ENHANCING THE DIVERSITY OF THE SCIENTIFIC WORKFORCE, AND DEVELOPING RESEARCH CAPACITY THROUGHOUT THE COUNTRY.
Place of Performance
Baltimore, Maryland 21218 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 292% from $884,633 to $3,465,167.
The Johns Hopkins University was awarded CMDB Program at JHU: Biomedical Scientist Training Project Grant T32GM141804 worth $3,465,167 from the National Institute of General Medical Sciences in July 2021 with work to be completed primarily in Baltimore Maryland United States. The grant has a duration of 5 years and was awarded through assistance program 93.859 Biomedical Research and Research Training. The Project Grant was awarded through grant opportunity National Institute of General Medical Sciences Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Institutional Research Training Grant (T32).

Status
(Ongoing)

Last Modified 7/3/25

Period of Performance
7/1/21
Start Date
6/30/26
End Date
88.0% Complete

Funding Split
$3.5M
Federal Obligation
$0.0
Non-Federal Obligation
$3.5M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to T32GM141804

Transaction History

Modifications to T32GM141804

Additional Detail

Award ID FAIN
T32GM141804
SAI Number
T32GM141804-1045872040
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NS00 NIH National Institute of General Medical Sciences
Funding Office
75NS00 NIH National Institute of General Medical Sciences
Awardee UEI
FTMTDMBR29C7
Awardee CAGE
5L406
Performance District
MD-07
Senators
Benjamin Cardin
Chris Van Hollen

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute of General Medical Sciences, National Institutes of Health, Health and Human Services (075-0851) Health research and training Grants, subsidies, and contributions (41.0) $1,733,471 100%
Modified: 7/3/25