RM1DA059375

Heal Initiative: Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On - 0BProject Summary/Abstract

Opioid overdose deaths reached the highest level ever in 2021. Medications to treat opioid use disorder (MOUD) can markedly reduce overdose risks when taken for long enough. More than 650,000 people receive MOUD in opioid treatment programs (OTPs) annually. Unfortunately, on average, less than half of patients stay in opioid use disorder (OUD) treatment for the recommended minimum 1 year of time.

OTP retention and outcome quality measures (i.e., "audit and feedback") may improve treatment retention rates and outcomes. Quality measures can also help monitor the effect of new OTP reimbursement and regulatory policies. Eventually, OTP quality measures could be incorporated into the federal government's public facing healthcare provider compare website. However, research is needed to determine how to most effectively create and disseminate OTP quality measures.

The literature on audit and feedback points to three features that influence the probability that measures will result in improved quality: (1) the characteristics of the measures and benchmarks, (2) the knowledge that providers have about how to improve the measures, and (3) the control that providers have over the factors that matter to improve the measure. This study will test approaches for optimizing each of these factors.

NIDA RFA-DA-23-046 is supporting multi-project OUD quality measurement and management research centers that pair researchers with partner organizations that have an OUD quality measurement and management strategy that research could advance. RTI International, University of California Los Angeles, and Beacon Health Connecticut are the research organizations leading this study. They are partnering with two organizations that need to develop an effective OTP quality measurement and management system: Baymark Health Services and the Los Angeles County Division of Substance Abuse Prevention and Control.

The team is implementing three inter-related research projects with the following overall aims:

Overall Aim 1. Create and psychometrically test OTP measures of retention, overdose emergency department visits, overdose hospitalizations, and mortality with benchmarks and toolkits describing how OTPs can improve retention.

Overall Aim 2. Test the effect of giving OTPs quality measures and information on how to improve retention (a retention toolkit), with and without quality improvement training, by conducting a clustered randomized trial that assigns OTPs to receive either: (1) retention and outcome measures with the toolkit; or (2) retention and outcome measures with the toolkit as well as quality improvement (QI) training (i.e., NIATX) (Arm 2), or (3) treatment as usual (control arm).

Overall Aim 3. Test the effect of aligning OTP-level and LA County population-level OUD measures on retention and outcomes in LA County relative to other counties in California.

Research Triangle Institute

TO SUPPORT BASIC AND CLINICAL NEUROSCIENCE, BIOMEDICAL, BEHAVIORAL AND SOCIAL SCIENCE, EPIDEMIOLOGIC, HEALTH SERVICES AND HEALTH DISPARITY RESEARCH. TO DEVELOP NEW KNOWLEDGE AND APPROACHES RELATED TO THE PREVENTION, DIAGNOSIS, TREATMENT, ETIOLOGY, AND CONSEQUENCES OF DRUG ABUSE AND ADDICTION, INCLUDING HIV/AIDS. TO SUPPORT RESEARCH TRAINING AND RESEARCH SCIENTIST DEVELOPMENT. TO SUPPORT DISSEMINATION OF RESEARCH FINDINGS. SMALL BUSINESS INNOVATION RESEARCH (SBIR) LEGISLATION IS INTENDED TO EXPAND AND IMPROVE THE SBIR PROGRAMS TO EMPHASIZE AND INCREASE PRIVATE SECTOR COMMERCIALIZATION OF TECHNOLOGY DEVELOPED THROUGH FEDERAL SBIR RESEARCH AND DEVELOPMENT, INCREASE SMALL BUSINESS PARTICIPATION IN FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTER AND ENCOURAGE PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN THE SBIR PROGRAM. THE LEGISLATION INTENDS THAT THE SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM STIMULATE AND FOSTER SCIENTIFIC AND TECHNOLOGICAL INNOVATION THROUGH COOPERATIVE RESEARCH AND DEVELOPMENT CARRIED OUT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, FOSTER TECHNOLOGY TRANSFER BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, TO INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTER AND ENCOURAGE PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN TECHNOLOGICAL INNOVATION.

93.279 - Drug Abuse and Addiction Research Programs

National Institute on Drug Abuse (NIDA) [HHS - NIH]

North Carolina United States

State-Wide

HEAL Initiative: Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On (RM1 - Clinical Trial Optional) (RFA-DA-23-046)

Amendment Since initial award the total obligations have increased 221% from $1,539,787 to $4,935,947.