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R21MH131043

Project Grant

Overview

Grant Description
Mobile application for early detection and intervention to reduce psychological distress in informal family caregivers of community dwelling adults with chronic disorders in Thailand - project summary

In lower-and-middle income countries (LMICs) like Thailand, family members providing care for adults with chronic disorders experience similar levels of mental health risks to that of their counterparts in higher income countries but have significantly more limited access to mental health care.

Despite comparable rates of mental health illness, family caregivers in LMICs have significantly more limited access to mental health care—due to a number of factors, including the limited number of providers trained in mental health care delivery, as well as sociocultural factors, such as stigma and privacy concerns, that may prevent those in need from seeking care, and/or result in significant delays in obtaining diagnosis and treatment.

Lack of treatment for caregiver mental health can lead to other adverse consequences for both caregivers and patients, including caregiver burnout, patient abuse, losing employment, and elevated financial strain.

Despite an accumulating body of evidence of the promise of mobile technology-based innovations for the treatment and prevention of mental health disorders in LMICs, as well the promise for improving mental health outcomes for family caregivers, there is limited research on the development, refinement, and implementation of evidence-based digital health technology into the routine care of family caregivers.

The goal of the 5-year project is to develop and test a culturally informed caregiver mental health mobile application (hereafter referred to as CAMMA) program that will deliver an evidence-based intervention to reduce mental health problems in family caregivers of adults with chronic disorders in Thailand.

The R21 project will allow us to systematically adapt evidence-based self-care intervention contents developed originally in the Western world and to make it compatible with the sociocultural and technological context in Thailand through qualitative and formative research.

The R33 will allow us to test the usability and effectiveness of the mobile technology-enabled intervention in reducing negative mental health outcomes in Thai family caregivers.

Specific aims of the R21 include:
1) Conducting qualitative research on family caregivers of persons with chronic disorders, focusing on their experience with mental health problems, caregiving practice, coping mechanisms, and socio-technological barriers to technology acceptance and use.
2) Develop a mobile application for the delivery of the CAMMA intervention.
3) Conduct a formative evaluation of the CAMMA intervention components to ensure acceptability and usability of individual intervention components.

Specific aims for the R33 include:
1) Assessing usability of the CAMMA intervention (including all intervention components).
2) Conducting a randomized clinical trial (RCT) to evaluate effectiveness of the CAMMA intervention in reducing psychological distress (depression, anxiety, psychological stress). We hypothesize that participants who receive the CAMMA intervention will show significantly higher reduction in depressive symptoms, anxiety, and psychological stress, compared to controls.
Funding Goals
NOT APPLICABLE
Place of Performance
Boston, Massachusetts 021156110 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 40252% from $1,000 to $403,524.
Brigham & Womens Hospital was awarded Mobile App Early Detection & Intervention in Thai Family Caregivers of Adults with Chronic Disorders Project Grant R21MH131043 worth $403,524 from Fogarty International Center in September 2023 with work to be completed primarily in Boston Massachusetts United States. The grant has a duration of 1 year 10 months and was awarded through assistance program 93.989 International Research and Research Training. The Project Grant was awarded through grant opportunity Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional).

Status
(Complete)

Last Modified 7/19/24

Period of Performance
9/1/23
Start Date
7/31/25
End Date
100% Complete

Funding Split
$403.5K
Federal Obligation
$0.0
Non-Federal Obligation
$403.5K
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R21MH131043

Subgrant Awards

Disclosed subgrants for R21MH131043

Transaction History

Modifications to R21MH131043

Additional Detail

Award ID FAIN
R21MH131043
SAI Number
R21MH131043-3850298607
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Nonprofit With 501(c)(3) IRS Status (Other Than An Institution Of Higher Education)
Awarding Office
75N700 NIH NATIONAL INSTITUTE OF MENTAL HEALTH
Funding Office
75NF00 NIH FOGARTY INTERNATIONAL CENTER
Awardee UEI
QN6MS4VN7BD1
Awardee CAGE
0W3J1
Performance District
MA-07
Senators
Edward Markey
Elizabeth Warren

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute of Mental Health, National Institutes of Health, Health and Human Services (075-0892) Health research and training Grants, subsidies, and contributions (41.0) $216,883 100%
Modified: 7/19/24