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R21EB033892

Project Grant

Overview

Grant Description
Engineered probiotics for closed-loop control of disease-associated gut metabolites in gut-on-chip models.
Funding Goals
TO SUPPORT HYPOTHESIS-, DESIGN-, TECHNOLOGY-, OR DEVICE-DRIVEN RESEARCH RELATED TO THE DISCOVERY, DESIGN, DEVELOPMENT, VALIDATION, AND APPLICATION OF TECHNOLOGIES FOR BIOMEDICAL IMAGING AND BIOENGINEERING. THE PROGRAM INCLUDES BIOMATERIALS (BIOMIMETICS, BIOPROCESSING, ORGANOGENESIS, REHABILITATION, TISSUE ENGINEERING, IMPLANT SCIENCE, MATERIAL SCIENCE, INTERFACE SCIENCE, PHYSICS AND STRESS ENGINEERING, TECHNOLOGY ASSESSMENT OF MATERIALS/DEVICES), BIOSENSORS/BIOTRANSDUCERS (TECHNOLOGY DEVELOPMENT, TECHNOLOGY ASSESSMENT, DEVELOPMENT OF ALGORITHMS, TELEMETRY), NANOTECHNOLOGY (NANOSCIENCE, BIOMIMETICS, DRUG DELIVERY SYSTEMS, DRUG BIOAVAILABILITY, MICROARRAY/COMBINATORIAL TECHNOLOGY, GENETIC ENGINEERING, COMPUTER SCIENCE, TECHNOLOGY ASSESSMENT), BIOINFORMATICS (COMPUTER SCIENCE, INFORMATION SCIENCE, MATHEMATICS, BIOMECHANICS, COMPUTATIONAL MODELING AND SIMULATION, REMOTE DIAGNOSIS AND THERAPY), IMAGING DEVICE DEVELOPMENT, BIOMEDICAL IMAGING TECHNOLOGY DEVELOPMENT, IMAGE EXPLOITATION, CONTRAST AGENTS, INFORMATICS AND COMPUTER SCIENCES RELATED TO IMAGING, MOLECULAR AND CELLULAR IMAGING, BIOELECTRICS/BIOMAGNETICS, ORGAN AND WHOLE BODY IMAGING, SCREENING FOR DISEASES AND DISORDERS, AND IMAGING TECHNOLOGY ASSESSMENT AND SURGERY (TECHNIQUE DEVELOPMENT AND TECHNOLOGY DEVELOPMENT).
Place of Performance
Massachusetts United States
Geographic Scope
State-Wide
Analysis Notes
Amendment Since initial award the End Date has been extended from 06/30/25 to 06/30/26 and the total obligations have increased 305% from $157,000 to $636,250.
Northeastern University was awarded Project Grant R21EB033892 worth $636,250 from the National Institute of Biomedical Imaging and Bioengineering in September 2022 with work to be completed primarily in Massachusetts United States. The grant has a duration of 3 years 9 months and was awarded through assistance program 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health. The Project Grant was awarded through grant opportunity NIBIB Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional).

Status
(Ongoing)

Last Modified 7/3/25

Period of Performance
9/15/22
Start Date
6/30/26
End Date
98.0% Complete

Funding Split
$636.2K
Federal Obligation
$0.0
Non-Federal Obligation
$636.2K
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R21EB033892

Transaction History

Modifications to R21EB033892

Additional Detail

Award ID FAIN
R21EB033892
SAI Number
R21EB033892-296639872
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75N800 NIH National Institute of Biomedical Imaging and Bioengineering
Funding Office
75N800 NIH National Institute of Biomedical Imaging and Bioengineering
Awardee UEI
HLTMVS2JZBS6
Awardee CAGE
9A140
Performance District
MA-90
Senators
Edward Markey
Elizabeth Warren

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Health and Human Services (075-0898) Health research and training Grants, subsidies, and contributions (41.0) $396,250 100%
Modified: 7/3/25