Search Prime Grants

R01MD019748

Project Grant

Overview

Grant Description
Actívatexto: Advancing smoking cessation and physical activity among Latinos - Project summary

Overcoming the burden of tobacco use among Latinos demands innovative, effective, accessible, culturally appropriate, and community-engaged solutions.

Over the past eight years, in partnership with the Latinos Contra El Tabaco (Spanish for: Latinos Against Tobacco) Community Advisory Board (CAB), our team has developed Decídetexto, the first culturally-accommodated smoking cessation text messaging intervention for Latinos (available in English and Spanish).

Our recently completed randomized controlled trial (RCT; N=457) demonstrated that Latinos receiving the Decídetexto intervention were significantly more likely than those receiving standard of care (smoking cessation printed materials) to be smoking abstinent at month 6 (34.1% vs 20.6%; P<0.001).

Despite the proven efficacy of Decídetexto among Latinos, we did not address the fact that 75% of participants did not meet the recommended levels of physical activity [at least 150 minutes of moderate to vigorous physical activity (MVPA) per week].

Moreover, we did not leverage the potential role of physical activity in enhancing cessation rates despite evidence suggesting that MVPA may enhance cessation rates.

Thus, we developed Actívatexto, an innovative mobile intervention that incorporates physical activity into the Decídetexto intervention.

Specifically, Actívatexto integrates four components: 1) a text messaging program that promotes both smoking cessation and physical activity, 2) wearable devices to monitor physical activity, 3) smoking cessation pharmacotherapy (i.e., nicotine replacement therapies), and 4) an online dashboard where the research team manages participants’ incoming and outgoing data from both the text messaging program and wearable devices.

Pilot tested among Latinos who smoke and do not meet the recommended levels of physical activity (N=20), Actívatexto generated high satisfaction, increased minutes of MVPA per week, and resulted in noteworthy cessation rates (70% of participants were smoking abstinent at month 3).

Our multidisciplinary team is uniquely poised to conduct the first comprehensive research effort to study the synergism of smoking cessation and physical activity in a mobile intervention among Latinos.

We will use a hybrid type I effectiveness-implementation research design to assess the efficacy of Actívatexto and the barriers and facilitators of its implementation.

Specific aims are:

Aim 1. Assess the efficacy of Actívatexto, a mobile intervention that promotes both smoking cessation and physical activity, compared to a mobile intervention that solely promotes smoking cessation, on smoking abstinence at month 6 among Latinos.

Aim 2. Assess physical activity, self-efficacy, and perceived stress as mediators of the presumed treatment effect on cotinine-verified 7-day point prevalence abstinence at month 6 among Latinos.

Aim 3. Examine the barriers and facilitators to implement Actívatexto among Latinos.
Funding Goals
NOT APPLICABLE
Place of Performance
Rochester, New York 146113847 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 375% from $796,253 to $3,779,424.
University Of Rochester was awarded Latino Smoking Cessation & Physical Activity : Actívatexto Project Project Grant R01MD019748 worth $3,779,424 from National Institute for Minority Health and Health Disparities in September 2024 with work to be completed primarily in Rochester New York United States. The grant has a duration of 4 years 8 months and was awarded through assistance program 93.307 Minority Health and Health Disparities Research. The Project Grant was awarded through grant opportunity Research Project Grant (Parent R01 Clinical Trial Required).

Status
(Ongoing)

Last Modified 6/5/26

Period of Performance
9/20/24
Start Date
5/31/29
End Date
37.0% Complete

Funding Split
$3.8M
Federal Obligation
$0.0
Non-Federal Obligation
$3.8M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R01MD019748

Subgrant Awards

Disclosed subgrants for R01MD019748

Transaction History

Modifications to R01MD019748

Additional Detail

Award ID FAIN
R01MD019748
SAI Number
R01MD019748-3363070353
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NE00 NIH National Insitute on Minority Health and Healh Disparities
Funding Office
75NE00 NIH National Insitute on Minority Health and Healh Disparities
Awardee UEI
F27KDXZMF9Y8
Awardee CAGE
03CZ7
Performance District
NY-25
Senators
Kirsten Gillibrand
Charles Schumer
Modified: 6/5/26