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R01MD019051

Project Grant

Overview

Grant Description
The impacts of adverse provider conditions on provider bias and health disparities - project summary

Healthcare disparities that adversely affect patients from racial and ethnic minoritized groups are often attributed to provider level factors such as implicit bias.

However, efforts to reduce disparities have been hindered by an incomplete knowledge of factors that leave providers more vulnerable to bias and their underlying mechanisms.

This proposal will address this critical knowledge gap by identifying situations that increase bias among healthcare providers that can be intervened on at the provider and system level.

The proposed research leverages theory from psychology and psychoneuroimmunology to document the impact of three adverse provider conditions (APCs) that could increase provider bias: (1) workplace demands (e.g., heightened levels of stress or burnout), (2) concerns about one’s own health, and (3) increased inflammation occurring during illness.

We hypothesize that when providers experience higher (versus lower) workplace demands, are more (versus less) concerned about their own health, and experience higher (versus lower) acute inflammation, they will demonstrate more bias against patients from racial and ethnic minoritized groups.

We will test our hypothesis in the context of abdominal pain treatment in emergency departments.

Participants will be attending physicians, nurse practitioners, physician’s assistants, and residents in emergency medicine and internal medicine hospitalists who treat abdominal pain for patients who are admitted.

We will address three specific aims to document effects of APCs on quality of care disparities.

To address Aim 1, we will use a correlational design to determine the relationship between APCs and standardized assessments of bias (implicit and explicit bias, perception of others’ pain, and social avoidance).

To address Aim 2, we will use a randomized controlled intervention design; we will use the influenza vaccine to simulate illness by experimentally increasing inflammation (indexed by pro-inflammatory cytokine levels).

Increases in cytokines are hypothesized to be positively associated with standardized assessments of bias.

To address Aim 3, we will use a prospective, longitudinal design to track provider illness symptoms, stress, burnout, and local cases of infectious illness over the course of a year.

These provider data will be correlated with patient data from abdominal pain cases treated by the provider on those days.

This study has high ecological validity and findings will identify distinct contributions of APCs to lower quality of care, especially for patients from racial and minoritized groups.

Overall, the proposed research will have widespread positive impact by outlining paths for novel interventions at multiple levels and domains of influence within the NIMHD research framework, such as by engaging administrator and clinical management stakeholders in conversations about consequences of staffing policies for health disparities.
Funding Goals
NOT APPLICABLE
Place of Performance
Arkansas United States
Geographic Scope
State-Wide
Analysis Notes
Amendment Since initial award the total obligations have increased 324% from $800,983 to $3,392,987.
University Of Arkansas was awarded Provider Conditions Impacting Bias in Healthcare: Addressing Disparities Project Grant R01MD019051 worth $3,392,987 from National Institute for Minority Health and Health Disparities in September 2024 with work to be completed primarily in Arkansas United States. The grant has a duration of 4 years 8 months and was awarded through assistance program 93.307 Minority Health and Health Disparities Research. The Project Grant was awarded through grant opportunity Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required).

Status
(Ongoing)

Last Modified 7/6/26

Period of Performance
9/20/24
Start Date
5/31/29
End Date
38.0% Complete

Funding Split
$3.4M
Federal Obligation
$0.0
Non-Federal Obligation
$3.4M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R01MD019051

Subgrant Awards

Disclosed subgrants for R01MD019051

Transaction History

Modifications to R01MD019051

Additional Detail

Award ID FAIN
R01MD019051
SAI Number
R01MD019051-3437149062
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NE00 NIH National Insitute on Minority Health and Healh Disparities
Funding Office
75NE00 NIH National Insitute on Minority Health and Healh Disparities
Awardee UEI
MECEHTM8DB17
Awardee CAGE
4B294
Performance District
AR-90
Senators
John Boozman
Tom Cotton
Modified: 7/6/26