R01MD016872

PROJECT 2VIDA! SARS-COV-2 VACCINE INTERVENTION DELIVERY FOR ADULTS IN SOUTHERN CALIFORNIA - PROJECT SUMMARY

AS OF JANUARY 2021, THE WORLD HEALTH ORGANIZATION (WHO) REPORTS THAT 89 MILLION CASES OF COVID-19 (SARS- COV-2) HAVE BEEN CONFIRMED AND HAVE RESULTED IN MORE THAN 1.9 MILLION DEATHS GLOBALLY.

CURRENTLY, THE UNITED STATES (U.S.) IS THE COUNTRY WITH THE LARGEST NUMBER OF INFECTIONS AND DEATHS DUE TO COVID-19, WITH A TOTAL OF 22 MILLION INFECTIONS AND 373,167 DEATHS.

FURTHERMORE, EARLY FINDINGS THAT HAVE EXAMINED COVID-19 DEMOGRAPHICS SHOW THAT RACIAL AND ETHNIC MINORITIES IN THE U.S. ARE BEARING A DISPROPORTIONATE NUMBER OF COVID-19 CASES AND DEATHS IRRESPECTIVE OF GEOGRAPHIC REGION.

WHILE THERE'S NO EVIDENCE THAT PEOPLE OF COLOR (POC) HAVE GENETIC OR BIOLOGICAL FACTORS THAT MAKE THEM MORE LIKELY TO BE AFFECTED BY COVID-19, THEY ARE MORE LIKELY TO HAVE UNDERLYING HEALTH CONDITIONS, LIVE IN MULTI-GENERATIONAL HOMES, LIVE IN DENSELY POPULATED AREAS, HAVE LIMITED ACCESS TO HEALTHCARE, AND HAVE JOBS THAT ARE CONSIDERED ESSENTIAL AND INVOLVE INTERACTION WITH THE PUBLIC.

ALL OF THESE FACTORS CONTRIBUTE TO HIGHER RATES OF INFECTION AND ADVERSE OUTCOMES DUE TO COVID-19.

ALTHOUGH COVID-19 PREVENTIVE BEHAVIORS SUCH AS HAND WASHING, MASK WEARING, AND SOCIAL DISTANCING HAVE BEEN SHOWN TO BE EFFECTIVE IN CURBING THE SPREAD OF THE VIRUS, ACCEPTANCE AND UPTAKE OF COVID-19 VACCINES WILL BE INSTRUMENTAL TO ENDING THE PANDEMIC.

HOWEVER, PUBLIC CONFIDENCE IN VACCINATION IS FRAGILE, ESPECIALLY AMONG RACIAL AND ETHNIC MINORITIES.

TO THIS END, WE HAVE FORMED AN INTERVENTION WORKING GROUP COMPRISED OF REPRESENTATIVES FROM COMMUNITY AND ACADEMIC ORGANIZATIONS TO ADDRESS CHALLENGES IN COVID-19 VACCINATION UPTAKE AMONG LATINX AND AFRICAN AMERICAN (AA) COMMUNITIES IN SOUTHERN CALIFORNIA BY USING A COMMUNITY-BASED PARTICIPATORY RESEARCH (CBPR) APPROACH.

PROJECT 2VIDA! (SARS-COV-2 VACCINE INTERVENTION DELIVERY FOR ADULTS IN SOUTHERN CALIFORNIA), IS A MULTILEVEL INTERVENTION TO ADDRESS INDIVIDUAL, SOCIAL, AND CONTEXTUAL FACTORS RELATED TO ACCESS TO, AND ACCEPTANCE OF, THE COVID-19 VACCINE AMONG LATINX AND AA ADULTS (>18 YEARS OLD) ACROSS SIX HIGHLY AFFECTED COMMUNITIES IN SOUTHEAST SAN DIEGO.

2VIDA! SEEKS TO IMPLEMENT AND ASSESS A COVID-19 VACCINATION PROTOCOL TO INCREASE INTEREST AND UPTAKE OF COVID-19 VACCINE, PROVIDE COVID-19 VACCINES IN THE COMMUNITY, AND ESTABLISH A MODEL FOR THE RAPID VACCINATION OF LATINO AND AA ADULTS THAT COULD BE GENERALIZABLE TO OTHER HIGHLY AFFECTED COMMUNITIES.

2VIDA! BUILDS ON OUR PREVIOUS CBPR EFFORTS AND CENTERS ON CONDUCTING COVID-19 COMMUNITY OUTREACH AND HEALTH PROMOTION, INDIVIDUAL AWARENESS AND EDUCATION, AND LINKAGES TO MEDICAL AND SUPPORTIVE SERVICES AND OFFERING THE COVID-19 VACCINE TO LATINX AND AA ADULTS (>18 YEARS OLD) IN COMMUNITY HEALTH CENTERS (CHC) AND MINI-VACCINATION STATIONS IN COMMUNITIES HIGHLY IMPACTED BY THE PANDEMIC IN SAN DIEGO COUNTY.

San Diego University Of California

TO SUPPORT BASIC, CLINICAL, SOCIAL, AND BEHAVIORAL RESEARCH, PROMOTE RESEARCH INFRASTRUCTURE AND TRAINING, FOSTER EMERGING PROGRAMS, DISSEMINATE INFORMATION, AND REACH OUT TO MINORITY AND OTHER HEALTH DISPARITY COMMUNITIES. THE NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH DISPARITIES (NIMHD) HAS ESTABLISHED PROGRAMS TO PURSUE THESE GOALS: (1) THE CENTERS OF EXCELLENCE PROGRAM PROMOTES RESEARCH TO IMPROVE MINORITY HEALTH AND/OR REDUCE AND ELIMINATE HEALTH DISPARITIES, BUILDS RESEARCH CAPACITY FOR MINORITY HEALTH AND HEALTH DISPARITIES RESEARCH IN ACADEMIC INSTITUTIONS, ENCOURAGES PARTICIPATION OF HEALTH DISPARITY GROUPS AND COMMUNITIES IN BIOMEDICAL AND BEHAVIORAL RESEARCH AND PREVENTION AND INTERVENTION ACTIVITIES, AND BRINGS TOGETHER INVESTIGATORS FROM RELEVANT DISCIPLINES IN A MANNER THAT WILL ENHANCE AND EXTEND THE EFFECTIVENESS OF THEIR RESEARCH, (2) NIMHD RESEARCH ENDOWMENT PROGRAM BUILDS RESEARCH CAPACITY AND INFRASTRUCTURE AT ELIGIBLE NIMHD CENTERS OF EXCELLENCE OR ELIGIBLE SECTION 736 HEALTH PROFESSIONS SCHOOLS (42 U.S.C. 293) TO FACILITATE MINORITY HEALTH AND OTHER HEALTH DISPARITIES RESEARCH TO CLOSE THE DISPARITY GAP IN THE BURDEN OF ILLNESS AND DEATH EXPERIENCED BY RACIAL AND ETHNIC MINORITY AMERICANS AND OTHER HEALTH DISPARITY POPULATIONS, PROMOTES A DIVERSE AND STRONG SCIENTIFIC, TECHNOLOGICAL AND ENGINEERING WORKFORCE, AND EMPHASIZES THE RECRUITMENT AND RETENTION OF UNDERREPRESENTED MINORITIES AND OTHER SOCIO-ECONOMICALLY DISADVANTAGED POPULATIONS IN THE FIELDS OF BIOMEDICAL AND BEHAVIORAL RESEARCH AND OTHER AREAS OF THE SCIENTIFIC WORKFORCE, (3) THE CENTERS OF EXCELLENCE ON ENVIRONMENTAL HEALTH DISPARITIES RESEARCH TO STIMULATE BASIC AND APPLIED RESEARCH ON ENVIRONMENTAL HEALTH DISPARITIES, (4) MINORITY HEALTH AND HEALTH DISPARITIES INTERNATIONAL RESEARCH TRAINING PROGRAM (MHIRT) AWARDS ENABLE U.S. INSTITUTIONS TO TAILOR SHORT-TERM BASIC SCIENCE, BIOMEDICAL AND BEHAVIORAL MENTORED STUDENT INTERNATIONAL RESEARCH TRAINING OPPORTUNITIES TO ADDRESS GLOBAL ISSUES RELATED TO UNDERSTANDING, REDUCING, AND ELIMINATING HEALTH DISPARITIES, (5) SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM INCREASES PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT, ENCOURAGES SMALL BUSINESS PARTICIPATION IN FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTERS AND ENCOURAGES PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN TECHNOLOGICAL INNOVATION, (6) SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM STIMULATES AND FOSTERS SCIENTIFIC AND TECHNOLOGICAL INNOVATION THROUGH COOPERATIVE RESEARCH DEVELOPMENT CARRIED OUT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, FOSTERS TECHNOLOGY TRANSFER BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, INCREASES PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTERS AND ENCOURAGES PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN TECHNOLOGICAL INNOVATION, (7) HEALTH DISPARITIES RESEARCH PROJECT GRANTS (RPG) SUPPORT INNOVATIVE PROJECTS TO ENHANCE OUR UNDERSTANDING OF BIOLOGICAL MECHANISMS, SOCIAL, BEHAVIORAL, AND HEALTH SERVICES THAT CAN DIRECTLY AND DEMONSTRABLY CONTRIBUTE TO THE IMPROVEMENT IN MINORITY HEALTH AND THE ELIMINATION OF HEALTH DISPARITIES WHICH INCLUDES THE (8) RESEARCH CENTERS IN MINORITY INSTITUTIONS (RCMI) BUILD CAPACITY FOR BASIC BIOMEDICAL AND/OR BEHAVIORAL RESEARCH, CLINICAL AND TRANSLATIONAL RESEARCH (RCTR) AND A NETWORK (RCTN) BY FOCUSING ON INSTITUTIONAL RESOURCE DEVELOPMENT, SUCH AS SUPPORTING CORE RESEARCH FACILITIES AND STAFF, PURCHASING ADVANCED INSTRUMENTATION, AND LABORATORY RENOVATIONS/ALTERATIONS (9) CLINICAL RESEARCH EDUCATION AND CAREER DEVELOPMENT (CRECD) AWARDS PROVIDE DIDACTIC TRAINING AND MENTORED CLINICAL RESEARCH EXPERIENCES TO DEVELOP INDEPENDENT RESEARCHERS WHO CAN LEAD CLINICAL RESEARCH STUDIES, ESPECIALLY THOSE ADDRESSING HEALTH DISPARITIES, (10) PATHWAY TO INDEPENDENCE AWARDS (K99/R00) TO INCREASE AND MAINTAIN A STRONG COHORT OF NEW AND TALENTED, NIH-SUPPORTED, INDEPENDENT INVESTIGATORS. (11) NIH RESEARCH CONFERENCE GRANT AND NIH RESEARCH CONFERENCE COOPERATIVE AGREEMENT PROGRAMS SUPPORT HIGH-QUALITY CONFERENCES THAT ARE RELEVANT TO THE MINORITY HEALTH AND HEALTH DISPARITIES, (12) TRANSDISCIPLINARY COLLABORATIVE CENTERS FOR HEALTH DISPARITIES RESEARCH COMPRISE REGIONAL COALITIONS OF ACADEMIC INSTITUTIONS, COMMUNITY ORGANIZATIONS, SERVICE PROVIDERS AND SYSTEMS, GOVERNMENT AGENCIES AND OTHER STAKEHOLDERS CONDUCTING COORDINATED RESEARCH, IMPLEMENTATION AND DISSEMINATION ACTIVITIES THAT TRANSCEND CUSTOMARY APPROACHES AND SILO ORGANIZATIONAL STRUCTURES TO ADDRESS CRITICAL QUESTIONS AT MULTIPLE LEVELS IN INNOVATIVE WAYS FOCUSED ON PRIORITY RESEARCH AREAS IN MINORITY HEALTH AND HEALTH DISPARITIES, (13) RUTH L. KIRSCHSTEIN NRSA INDIVIDUAL PREDOCTORAL FELLOWSHIP

93.307 - Minority Health and Health Disparities Research

National Institute for Minority Health and Health Disparities (NIMHD) [HHS - NIH]

La Jolla, California 92093 United States

Single Zip Code

Research Project Grant (Parent R01 Clinical Trial Required) (PA-20-183)

Amendment Since initial award the total obligations have increased 355% from $675,714 to $3,077,210.