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R01HL162598

Project Grant

Overview

Grant Description
A Sensor-Controlled Digital Game-Based Approach to Improve Self-Care Behaviors Among Adults Diagnosed with Hypertension in a Native American Community - Project Summary/Abstract

Cardiovascular disease is the leading cause of death among Native Americans (NAs). The Lumbee tribal community in Robeson County, North Carolina, suffers from severe disparities related to cardiovascular disease incidence and mortality. Hypertension (HTN) strongly elevates the morbidity and mortality risks related to cardiovascular disease. Lifestyle modifications promoted by U.S. HTN guidelines include modifiable self-care behaviors such as regular physical activity, which is associated with lower blood pressure, reduced cardiovascular risk, and beneficial cardiac structural remodeling. Therefore, motivating physical activity behaviors would be key to cardiovascular health promotion efforts among the Lumbee tribal community.

One promising approach is the use of sensor-controlled digital games (SCDGs), which offer affordable, portable, and scalable tools to facilitate engagement in HTN self-care behaviors while being enjoyable and easy to use. The SCDG intervention integrates HTN participants' behavioral data from an activity tracker sensor to activate game progress, rewards, and feedback. The primary goal of this study is to test a culturally adapted SCDG intervention (N-SCDG) for improving daily physical activity self-care behaviors among Lumbee tribal adults with HTN and examine approaches for sustaining the impact of the N-SCDG at the community level.

For Aim 1, we will use a community-based participatory approach to culturally adapt an SCDG intervention that we have already developed for mobile smartphones to motivate sustained physical activity self-care behaviors among NA adults with HTN. For Aim 2, using a randomized controlled clinical trial, we will compare the N-SCDG intervention versus a sensor-only control for the primary outcome of engagement in the HTN self-care behavior of physical activity and the secondary outcomes of HTN self-care knowledge, self-care behaviors, self-efficacy, systolic and diastolic blood pressure, cardiac hospitalization, and quality of life at baseline and at 3 and 6 months.

For our sample, we will recruit adults aged 18 years or older from tribal-affiliated cardiac clinics in Robeson County. We will randomize 220 participants to either the N-SCDG intervention group, in which participants will receive sensors that track physical activity and will play the N-SCDG on a mobile smartphone, or a control group that will receive sensors, an app that tracks physical activity, and standardized written HTN educational materials.

For Aim 3, we will evaluate the sustainability of the N-SCDG intervention in the Lumbee tribal community through qualitative interviews with study participants and community leaders and train Lumbee community members to sustain and disseminate the N-SCDG intervention for building community capacity for HTN management.

This project will generate insight and guidance for scalable and easy-to-use digital gaming solutions to motivate HTN self-care behaviors and improve health outcomes among NA individuals with HTN.
Funding Goals
NOT APPLICABLE
Place of Performance
Austin, Texas 787121918 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 385% from $691,344 to $3,352,294.
University Of Texas At Austin was awarded Native American Hypertension Self-Care Game: Improving Cardiovascular Health Project Grant R01HL162598 worth $3,352,294 from National Heart Lung and Blood Institute in May 2022 with work to be completed primarily in Austin Texas United States. The grant has a duration of 5 years and was awarded through assistance program 93.837 Cardiovascular Diseases Research. The Project Grant was awarded through grant opportunity Intervention Research to Improve Native American Health (R01 Clinical Trial Optional).

Status
(Ongoing)

Last Modified 5/21/26

Period of Performance
5/1/22
Start Date
4/30/27
End Date
81.0% Complete

Funding Split
$3.4M
Federal Obligation
$0.0
Non-Federal Obligation
$3.4M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R01HL162598

Subgrant Awards

Disclosed subgrants for R01HL162598

Transaction History

Modifications to R01HL162598

Additional Detail

Award ID FAIN
R01HL162598
SAI Number
R01HL162598-2846101917
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NH00 NIH National Heart, Lung, and Blood Institute
Funding Office
75NH00 NIH National Heart, Lung, and Blood Institute
Awardee UEI
V6AFQPN18437
Awardee CAGE
9B981
Performance District
TX-25
Senators
John Cornyn
Ted Cruz

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Heart, Lung, and Blood Institute, National Institutes of Health, Health and Human Services (075-0872) Health research and training Grants, subsidies, and contributions (41.0) $1,379,468 100%
Modified: 5/21/26