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R01HL160618

Project Grant

Overview

Grant Description
The Together Everyone Achieves More Physical Activity Trial (TEAM-PA) - Project Summary/Abstract

African American (AA) women experience disproportionately higher rates of chronic diseases compared to white women, including being twice as likely to die from cardiovascular disease. Physical activity (PA) is a key protective factor for reducing the risk of chronic diseases, yet only 35% of AA women meet national PA guidelines.

Persistent disparities in chronic disease and premature death among African American women across the adult lifespan highlight the need for developing effective interventions for increasing PA among AA women. We propose that community settings hold tremendous promise as an important context for reaching AA women, but the role of social affiliation has been understudied in past community-based interventions as a key mechanism for engaging AA women in long-term PA.

A variety of theories have highlighted the importance of social affiliation for health promotion and have defined social affiliation through several distinct but related constructs. Social Cognitive Theory (SCT) proposes that the group context promotes social learning and collective efficacy, while Self-Determination Theory (SDT) and Group Dynamics Theory (GDT) have emphasized the importance of positive interactions between group members to promote relatedness, reciprocal support, and group cohesion.

Social affiliation within group-based programs may be especially important to AA women, given that collectivism (belief in the importance of advancing the group over the individual) is a prominent cultural value for many AAs. Despite converging evidence highlighting the importance of social affiliation from a motivational and cultural perspective, this factor has been minimally integrated within intervention designs and rarely targeted as a central mechanism for increasing PA.

Our investigative team provides strong preliminary data for expanding on previous community-based PA interventions for inactive AA women by targeting social affiliation through a combination of collaborative and competitive strategies. Drawing from SDT, SCT, GDT, and a cultural values framework, the Together Everyone Achieve More Physical Activity (TEAM-PA) trial evaluates the efficacy of a group-based social affiliation intervention (vs. a standard group-delivered PA comparison program) for increasing PA among inactive AA women.

Using a group cohort randomized design implemented at community centers over five years, the primary aim of this study is to evaluate the efficacy of the 10-week TEAM-PA group-based intervention (vs. comparison program) on increasing accelerometry-assessed minutes per day of total PA (light to vigorous activities) from baseline to post-intervention and maintenance at a 6-month follow-up [Primary Aim 1]. Additionally, we will evaluate the impact of the TEAM-PA intervention on secondary outcomes (percentage meeting national recommendations for PA, light PA, sedentary behavior, body mass index, blood pressure) [Secondary Aims 1-2] and potential mediators of the intervention effect on changes in PA [Secondary Aim 3].
Funding Goals
TO FOSTER HEART AND VASCULAR RESEARCH IN THE BASIC, TRANSLATIONAL, CLINICAL AND POPULATION SCIENCES, AND TO FOSTER TRAINING TO BUILD TALENTED YOUNG INVESTIGATORS IN THESE AREAS, FUNDED THROUGH COMPETITIVE RESEARCH TRAINING GRANTS. SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM: TO STIMULATE TECHNOLOGICAL INNOVATION, USE SMALL BUSINESS TO MEET FEDERAL RESEARCH AND DEVELOPMENT NEEDS, FOSTER AND ENCOURAGE PARTICIPATION IN INNOVATION AND ENTREPRENEURSHIP BY SOCIALLY AND ECONOMICALLY DISADVANTAGED PERSONS, AND INCREASE PRIVATE-SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT FUNDING. SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM: TO STIMULATE TECHNOLOGICAL INNOVATION, FOSTER TECHNOLOGY TRANSFER THROUGH COOPERATIVE R&D BETWEEN SMALL BUSINESSES AND RESEARCH INSTITUTIONS, AND INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL R&D.
Place of Performance
Columbia, South Carolina 292083403 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 328% from $744,930 to $3,186,068.
University Of South Carolina was awarded TEAM-PA Trial: Increasing PA in Inactive AA Women Project Grant R01HL160618 worth $3,186,068 from National Heart Lung and Blood Institute in January 2022 with work to be completed primarily in Columbia South Carolina United States. The grant has a duration of 5 years and was awarded through assistance program 93.837 Cardiovascular Diseases Research. The Project Grant was awarded through grant opportunity Research Project Grant (Parent R01 Clinical Trial Required).

Status
(Ongoing)

Last Modified 1/21/25

Period of Performance
1/15/22
Start Date
12/31/26
End Date
73.0% Complete

Funding Split
$3.2M
Federal Obligation
$0.0
Non-Federal Obligation
$3.2M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R01HL160618

Transaction History

Modifications to R01HL160618

Additional Detail

Award ID FAIN
R01HL160618
SAI Number
R01HL160618-2454221479
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NH00 NIH NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Funding Office
75NH00 NIH NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Awardee UEI
J22LNTMEDP73
Awardee CAGE
4B489
Performance District
SC-06
Senators
Lindsey Graham
Tim Scott

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Heart, Lung, and Blood Institute, National Institutes of Health, Health and Human Services (075-0872) Health research and training Grants, subsidies, and contributions (41.0) $1,480,173 81%
Office of the Director, National Institutes of Health, Health and Human Services (075-0846) Health research and training Grants, subsidies, and contributions (41.0) $352,998 19%
Modified: 1/21/25