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R01HD103902

Project Grant

Overview

Grant Description
Child-Adult Relationship Enhancement in Primary Care: Effectiveness Trial of a Primary Care-Based Parenting Intervention to Prevent Child Maltreatment - Project Summary/Abstract

Child maltreatment (CM) is a pervasive public health problem, and there is a critical need for brief, effective, scalable prevention interventions. Problematic parent-child relationships lie at the heart of CM. Parents who maltreat their children are more likely to have punitive parenting styles characterized by high rates of negative interaction and ineffective discipline strategies with over-reliance on punishment. Harsh, reactive parenting can contribute to the development of child behavioral problems which, in turn, can increase parental stress and lead to escalation of negative parenting behaviors, including abusive and neglectful parenting. Thus, parenting interventions that strengthen parent-child relationships, teach positive discipline techniques, decrease harsh parenting, and decrease child behavioral problems hold promise as CM prevention strategies.

Challenges in engaging parents, particularly low-income and minority parents, and a lack of knowledge regarding effective implementation strategies, however, have greatly limited the reach and impact of parenting interventions. To address these challenges, our interdisciplinary team from the University of North Carolina and Children's Hospital of Philadelphia collaborated in implementing and evaluating Child Adult Relationship Enhancement in Primary Care (PRICARE)/Criando Niños con Cariño. PRICARE/Cariño is distinct from other programs because it was (1) developed and iteratively adapted with input from racially and ethnically diverse families, including low-income families, and (2) designed specifically for implementation in primary care with inclusion of strategies to align with usual-care workflow to increase uptake and retention.

In randomized controlled trials (RCTs), PRICARE has demonstrated success in engaging parents, promoting positive parenting, reducing parent stress, and improving child behaviors. The objective of this project, "Child-Adult Relationship Enhancement in Primary Care: Effectiveness Trial of a Primary Care-Based Parenting Intervention to Prevent Child Maltreatment," is to conduct a multi-site RCT of PRICARE/Cariño plus usual care vs. usual care among 1932 parents and their 2-6-year-old children with Medicaid/CHIP/no insurance from 6 clinics. We will examine the effectiveness of PRICARE/Cariño on reducing suspected CM, in addition to reducing proximal CM-related outcomes (child behavior problems, parent stress, harsh/neglectful parenting). By testing proximal outcomes in addition to the more distal outcome of CM, this study will help to elucidate the mechanisms of change and advance the science of CM prevention.

Finally, in this study, we will also identify PRICARE/Cariño implementation determinants and examine their relationship to implementation outcomes. If successful, results will be used to seek funding from state agencies and payers to sustain PRICARE/Cariño in primary care, while continuing to refine and study implementation and dissemination strategies, with the ultimate goal of achieving levels of exposure sufficient for breaking the intergenerational transmission of CM. Inclusion of consent for longitudinal data collection will facilitate future longitudinal studies of the impact of PRICARE/Cariño on additional outcomes.
Funding Goals
TO CONDUCT AND SUPPORT LABORATORY RESEARCH, CLINICAL TRIALS, AND STUDIES WITH PEOPLE THAT EXPLORE HEALTH PROCESSES. NICHD RESEARCHERS EXAMINE GROWTH AND DEVELOPMENT, BIOLOGIC AND REPRODUCTIVE FUNCTIONS, BEHAVIOR PATTERNS, AND POPULATION DYNAMICS TO PROTECT AND MAINTAIN THE HEALTH OF ALL PEOPLE. TO EXAMINE THE IMPACT OF DISABILITIES, DISEASES, AND DEFECTS ON THE LIVES OF INDIVIDUALS. WITH THIS INFORMATION, THE NICHD HOPES TO RESTORE, INCREASE, AND MAXIMIZE THE CAPABILITIES OF PEOPLE AFFECTED BY DISEASE AND INJURY. TO SPONSOR TRAINING PROGRAMS FOR SCIENTISTS, DOCTORS, AND RESEARCHERS TO ENSURE THAT NICHD RESEARCH CAN CONTINUE. BY TRAINING THESE PROFESSIONALS IN THE LATEST RESEARCH METHODS AND TECHNOLOGIES, THE NICHD WILL BE ABLE TO CONDUCT ITS RESEARCH AND MAKE HEALTH RESEARCH PROGRESS UNTIL ALL CHILDREN, ADULTS, FAMILIES, AND POPULATIONS ENJOY GOOD HEALTH. THE MISSION OF THE NICHD IS TO ENSURE THAT EVERY PERSON IS BORN HEALTHY AND WANTED, THAT WOMEN SUFFER NO HARMFUL EFFECTS FROM REPRODUCTIVE PROCESSES, AND THAT ALL CHILDREN HAVE THE CHANCE TO ACHIEVE THEIR FULL POTENTIAL FOR HEALTHY AND PRODUCTIVE LIVES, FREE FROM DISEASE OR DISABILITY, AND TO ENSURE THE HEALTH, PRODUCTIVITY, INDEPENDENCE, AND WELL-BEING OF ALL PEOPLE THROUGH OPTIMAL REHABILITATION.
Place of Performance
Chapel Hill, North Carolina 27599 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 468% from $589,466 to $3,346,879.
University Of North Carolina At Chapel Hill was awarded Preventing Child Maltreatment: Primary Care-Based Parenting Intervention Project Grant R01HD103902 worth $3,346,879 from the National Institute of Child Health and Human Development in August 2021 with work to be completed primarily in Chapel Hill North Carolina United States. The grant has a duration of 5 years and was awarded through assistance program 93.865 Child Health and Human Development Extramural Research. The Project Grant was awarded through grant opportunity NICHD Research Project Grant (R01 - Clinical Trial Required).

Status
(Ongoing)

Last Modified 7/3/25

Period of Performance
8/1/21
Start Date
7/31/26
End Date
81.0% Complete

Funding Split
$3.3M
Federal Obligation
$0.0
Non-Federal Obligation
$3.3M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R01HD103902

Transaction History

Modifications to R01HD103902

Additional Detail

Award ID FAIN
R01HD103902
SAI Number
R01HD103902-3131882911
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NT00 NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development
Funding Office
75NT00 NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development
Awardee UEI
D3LHU66KBLD5
Awardee CAGE
4B856
Performance District
NC-04
Senators
Thom Tillis
Ted Budd

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute of Child Health and Human Development, National Institutes of Health, Health and Human Services (075-0844) Health research and training Grants, subsidies, and contributions (41.0) $1,352,605 100%
Modified: 7/3/25