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R01DK132386

Project Grant

Overview

Grant Description
Optimizing a Couples-Based mHealth Intervention for Weight Management - Abstract

Weight is a dyadic health issue in married and cohabitating couples. Partners tend to enter this critical interpersonal relationship with a similar weight status and gain weight together over time. Despite this shared risk, standard behavioral interventions focus on individuals, not couples, largely ignoring the inherently dyadic nature of weight management.

Early tests of couples weight loss programs lacked a clear conceptualization guiding spouse/partner involvement and results were mixed. Yet there are promising signals – theoretical and empirical – to guide how couples' relationships can be harnessed to improve weight loss outcomes.

The proposed study aims to build on this work and develop an efficacious couples-based mHealth approach to weight loss using the Multiphase Optimization Strategy (MOST) framework.

In the preparation phase, we developed a conceptual model drawing on Transactive Goal Dynamics Theory, our own pilot work, and the published literature that includes four dyadic intervention components: dyadic action planning, joint feedback on goal progress, autonomy support training, and home environment modifications.

In the proposed optimization phase, we plan to conduct an innovative and efficient factorial experiment to identify which combination of the four dyadic intervention components – when added to the core components of a standard behavioral weight loss program (BWL; e.g., weekly lessons, self-monitoring, feedback) – results in the greatest weight loss at 6 months (primary outcome).

The 6-month intervention will be delivered to married and cohabitating couples (N=368 dyads) via a native smartphone app to enhance the reach of the intervention, minimize burden, and attract couples with more demographic and relationship diversity. Assessments will occur at 0, 3, and 6 months.

Weight loss and theoretical mediators as framed by Transactive Goal Dynamics Theory (e.g., goal coordination) will be assessed along with hypothesized moderators (relationship and demographic variables).

The set of novel dyadic intervention components that maximizes weight loss will be selected for inclusion in an optimized intervention package to be evaluated in a future randomized controlled trial.

The proposed study is the first test of a fully mHealth weight loss intervention for married and cohabitating couples. Using the MOST design, it will advance both intervention and theory development by isolating active dyadic intervention components and their mechanisms of action.
Funding Goals
NOT APPLICABLE
Place of Performance
Storrs Mansfield, Connecticut 062691248 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 372% from $712,954 to $3,363,183.
University Of Connecticut was awarded Optimizing Couples-Based mHealth Intervention for Weight Management Project Grant R01DK132386 worth $3,363,183 from the National Institute of Diabetes and Digestive and Kidney Diseases in May 2022 with work to be completed primarily in Storrs Mansfield Connecticut United States. The grant has a duration of 5 years and was awarded through assistance program 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research. The Project Grant was awarded through grant opportunity Research Project Grant (Parent R01 Clinical Trial Required).

Status
(Ongoing)

Last Modified 5/21/26

Period of Performance
5/15/22
Start Date
4/30/27
End Date
81.0% Complete

Funding Split
$3.4M
Federal Obligation
$0.0
Non-Federal Obligation
$3.4M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R01DK132386

Subgrant Awards

Disclosed subgrants for R01DK132386

Transaction History

Modifications to R01DK132386

Additional Detail

Award ID FAIN
R01DK132386
SAI Number
R01DK132386-2170984906
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NK00 NIH National Institute of Diabetes and Digestive and Kidney Diseases
Funding Office
75NK00 NIH National Institute of Diabetes and Digestive and Kidney Diseases
Awardee UEI
WNTPS995QBM7
Awardee CAGE
01NY7
Performance District
CT-02
Senators
Richard Blumenthal
Christopher Murphy

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Health and Human Services (075-0884) Health research and training Grants, subsidies, and contributions (41.0) $1,400,616 100%
Modified: 5/21/26