R01DA056417
Project Grant
Overview
Grant Description
A Multiregional RCT of Parenting in 2 Worlds for Urban Indian Families - Project Summary/Abstract
A large and rapidly growing majority of American Indian/Alaska Native (AI) families now reside in urban areas. Although they experience severe health disparities associated with substance abuse, risky sexual behavior, depression, and suicide, few evidence-based prevention interventions address their distinctive needs. Family disruption, stresses due to migration and poverty, and cultural and social losses are often implicated in adverse health outcomes for urban AI families. By improving effective parenting skills and overall family functioning, culturally grounded parenting interventions enable parents to model and promote their children's well-being and reduce their children's vulnerability to risk behaviors.
The proposed study extends the project team's prior research on a culturally grounded parenting intervention for urban AIs, Parenting in 2 Worlds (P2W), which was co-developed with a coalition of urban Indian non-profit organizations, tested in three Arizona cities, and demonstrated efficacy. The research team joins two AI and two non-AI investigators, who together have extensive experience conducting collaborative research with AI populations in urban and tribal settings.
This proposed multi-regional study will create new knowledge in four areas. First, the study will test P2W's effectiveness beyond Arizona in improving parenting and family functioning among a wider and more diverse group of urban AI communities located in cities spread across four regions: Northeast (Buffalo/Niagara), Midwest (St. Paul/Minneapolis), Mountain (Denver), and Southwest (Phoenix). Through the auspices of collaborating urban Indian center partners, the trial will recruit 720 families of AI youth aged 12-17 (180 per city) and individually randomize them to receive P2W or an informational family health curriculum.
Second, the study will test for moderators of the effectiveness of P2W, whether desired outcomes vary by the level of socioeconomic vulnerability, experiences of historical loss, or AI cultural identity of the parent participants.
Third, the study will expand on the original Arizona trial to examine the adolescent's reports on family functioning and an enlarged range of youth health behaviors potentially impacted by the P2W intervention, including mental health (depressive symptoms, suicidality) as well as substance use and risky sexual behaviors.
Fourth, the study will test for mediation - whether positive changes in parenting and family functioning that result from P2W lead to changes in the youth health behaviors. This would be the first cross-site multiregional trial of a culturally grounded parenting intervention designed specifically for urban AIs. It will advance critical knowledge on community prevention interventions for an underserved group severely affected by health disparities and establish whether urban Indian centers and their communities can readily employ P2W to strengthen urban AI families and promote the behavioral health of their youth. It will also provide a foundation for advancing knowledge on effective prevention interventions in urban AI communities that have different migration histories and tribal compositions.
A large and rapidly growing majority of American Indian/Alaska Native (AI) families now reside in urban areas. Although they experience severe health disparities associated with substance abuse, risky sexual behavior, depression, and suicide, few evidence-based prevention interventions address their distinctive needs. Family disruption, stresses due to migration and poverty, and cultural and social losses are often implicated in adverse health outcomes for urban AI families. By improving effective parenting skills and overall family functioning, culturally grounded parenting interventions enable parents to model and promote their children's well-being and reduce their children's vulnerability to risk behaviors.
The proposed study extends the project team's prior research on a culturally grounded parenting intervention for urban AIs, Parenting in 2 Worlds (P2W), which was co-developed with a coalition of urban Indian non-profit organizations, tested in three Arizona cities, and demonstrated efficacy. The research team joins two AI and two non-AI investigators, who together have extensive experience conducting collaborative research with AI populations in urban and tribal settings.
This proposed multi-regional study will create new knowledge in four areas. First, the study will test P2W's effectiveness beyond Arizona in improving parenting and family functioning among a wider and more diverse group of urban AI communities located in cities spread across four regions: Northeast (Buffalo/Niagara), Midwest (St. Paul/Minneapolis), Mountain (Denver), and Southwest (Phoenix). Through the auspices of collaborating urban Indian center partners, the trial will recruit 720 families of AI youth aged 12-17 (180 per city) and individually randomize them to receive P2W or an informational family health curriculum.
Second, the study will test for moderators of the effectiveness of P2W, whether desired outcomes vary by the level of socioeconomic vulnerability, experiences of historical loss, or AI cultural identity of the parent participants.
Third, the study will expand on the original Arizona trial to examine the adolescent's reports on family functioning and an enlarged range of youth health behaviors potentially impacted by the P2W intervention, including mental health (depressive symptoms, suicidality) as well as substance use and risky sexual behaviors.
Fourth, the study will test for mediation - whether positive changes in parenting and family functioning that result from P2W lead to changes in the youth health behaviors. This would be the first cross-site multiregional trial of a culturally grounded parenting intervention designed specifically for urban AIs. It will advance critical knowledge on community prevention interventions for an underserved group severely affected by health disparities and establish whether urban Indian centers and their communities can readily employ P2W to strengthen urban AI families and promote the behavioral health of their youth. It will also provide a foundation for advancing knowledge on effective prevention interventions in urban AI communities that have different migration histories and tribal compositions.
Awardee
Funding Goals
NOT APPLICABLE
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Tempe,
Arizona
852876011
United States
Geographic Scope
Single Zip Code
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 330% from $700,990 to $3,015,839.
Arizona State University was awarded
Urban Indian Family Health: Culturally Grounded Parenting Intervention Study
Project Grant R01DA056417
worth $3,015,839
from National Institute on Drug Abuse in June 2022 with work to be completed primarily in Tempe Arizona United States.
The grant
has a duration of 4 years 10 months and
was awarded through assistance program 93.279 Drug Abuse and Addiction Research Programs.
The Project Grant was awarded through grant opportunity Intervention Research to Improve Native American Health (R01 Clinical Trial Optional).
Status
(Ongoing)
Last Modified 5/21/26
Period of Performance
6/1/22
Start Date
4/30/27
End Date
Funding Split
$3.0M
Federal Obligation
$0.0
Non-Federal Obligation
$3.0M
Total Obligated
Activity Timeline
Subgrant Awards
Disclosed subgrants for R01DA056417
Transaction History
Modifications to R01DA056417
Additional Detail
Award ID FAIN
R01DA056417
SAI Number
R01DA056417-2088318383
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75N600 NIH National Insitute on Drug Abuse
Funding Office
75N600 NIH National Insitute on Drug Abuse
Awardee UEI
NTLHJXM55KZ6
Awardee CAGE
4B293
Performance District
AZ-04
Senators
Kyrsten Sinema
Mark Kelly
Mark Kelly
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| National Institute on Drug Abuse, National Institutes of Health, Health and Human Services (075-0893) | Health research and training | Grants, subsidies, and contributions (41.0) | $1,288,723 | 100% |
Modified: 5/21/26