R01DA056265

The Impact of Racism on Trajectories of Substance Use, Mental Health, and Legal System Contact from Adolescence to Young Adulthood - Project Summary

Data consistently demonstrate alarming racial disparities among youth and adults impacted by the legal system, and multiple studies have documented that justice-impacted youth have substantially higher rates of psychiatric needs, substance use, and HIV/STI risk behaviors than youth who have not had juvenile legal system contact. However, research elucidating the impact of structural, cultural, and individual racism on the health and legal outcomes and disparities of justice-impacted ethnoracial minoritized youth and families is nascent.

This study will advance the science in structural racism and discrimination (SRD) and its influence on public health and legal inequities by leveraging an existing statewide longitudinal dataset from Project EPICC. Additionally, the study will follow up with 300 previously enrolled youth and caregivers (N=300 dyads or 600 participants total) to conduct once annual follow-up assessments and life course interviews.

Informed by ecodevelopmental theory, Project EPICC followed 401 youth and an involved caregiver (55% ethnoracial minoritized youth) for two years starting from the time of first-ever youth contact with the juvenile legal system. Data are available on the longitudinal trajectories of substance use, psychiatric symptoms, HIV/STI risk behaviors, and recidivism, as well as the multiple contributing risk and protective influences (individual, family, and extrafamilial) on youth trajectories.

Project EPICC-2 will expand the ecodevelopmental framework to study the longitudinal impact of structural racism and discrimination on trajectories of ethnoracial minoritized youth's substance use, psychiatric, sexual and reproductive health, and legal outcomes during adolescence and into young adulthood. Using statewide administrative data, the study will expand original primary outcomes to include substance use and psychiatric services utilization to understand more about the direct influence of structural racism and discrimination on justice-impacted young adult healthcare services access and equity.

Annual life course interviews with a stratified random subsample of 50 young adults and 50 caregivers will provide a more nuanced qualitative and contextual understanding of the impact of structural racism on adolescent, young adult, and family experiences and trajectories.

EPICC-2 will leverage an existing longitudinal dataset, pre-existing relationships with a large sample of justice-impacted families, an ecodevelopmental and intersectional (race, ethnicity, sex, gender, socioeconomic status) framework, an intergenerational approach, and an accomplished multidisciplinary study team to answer critically important questions in the field of adolescent and young adult health disparities.

San Francisco Regents Of The University Of California

TO SUPPORT BASIC AND CLINICAL NEUROSCIENCE, BIOMEDICAL, BEHAVIORAL AND SOCIAL SCIENCE, EPIDEMIOLOGIC, HEALTH SERVICES AND HEALTH DISPARITY RESEARCH. TO DEVELOP NEW KNOWLEDGE AND APPROACHES RELATED TO THE PREVENTION, DIAGNOSIS, TREATMENT, ETIOLOGY, AND CONSEQUENCES OF DRUG ABUSE AND ADDICTION, INCLUDING HIV/AIDS. TO SUPPORT RESEARCH TRAINING AND RESEARCH SCIENTIST DEVELOPMENT. TO SUPPORT DISSEMINATION OF RESEARCH FINDINGS. SMALL BUSINESS INNOVATION RESEARCH (SBIR) LEGISLATION IS INTENDED TO EXPAND AND IMPROVE THE SBIR PROGRAMS TO EMPHASIZE AND INCREASE PRIVATE SECTOR COMMERCIALIZATION OF TECHNOLOGY DEVELOPED THROUGH FEDERAL SBIR RESEARCH AND DEVELOPMENT, INCREASE SMALL BUSINESS PARTICIPATION IN FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTER AND ENCOURAGE PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN THE SBIR PROGRAM. THE LEGISLATION INTENDS THAT THE SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM STIMULATE AND FOSTER SCIENTIFIC AND TECHNOLOGICAL INNOVATION THROUGH COOPERATIVE RESEARCH AND DEVELOPMENT CARRIED OUT BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, FOSTER TECHNOLOGY TRANSFER BETWEEN SMALL BUSINESS CONCERNS AND RESEARCH INSTITUTIONS, TO INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT, AND FOSTER AND ENCOURAGE PARTICIPATION OF SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESS CONCERNS AND WOMEN-OWNED SMALL BUSINESS CONCERNS IN TECHNOLOGICAL INNOVATION.

93.279 - Drug Abuse and Addiction Research Programs

National Institute on Drug Abuse (NIDA) [HHS - NIH]

San Francisco, California 94110 United States

Single Zip Code

Understanding and Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 Clinical Trial Optional) (RFA-MD-21-004)

Amendment Since initial award the total obligations have increased 375% from $765,488 to $3,639,324.