R01AG072569
Project Grant
Overview
Grant Description
Title: Mental Health Experiences of Hispanic and Latinx ADRD Caregivers - Project Summary/Abstract
Hispanic and Latinx (H&L) family caregivers of individuals living with Alzheimer's Disease and Related Dementias (ADRD) are uniquely at risk for poor mental health outcomes due to increased stress associated with earlier ADRD onset and increased severity of symptoms among the H&L population.
While the link between caregiving-related stress and health outcomes is well-documented among the general ADRD caregiver population, limited knowledge on dynamic predictors of H&L ADRD caregiver mental health trajectories exists. Further, the interactions between risk/protective and cultural factors that increase resilience and reduce the risk of poor mental health outcomes over time are relatively unknown.
The purpose of this study is to investigate how interactions between contextual, individual-level, and cultural factors impact daily and long-term patterns of depression and anxiety symptoms among H&L caregivers. Using an innovative, multi-time scale design and analytical strategy grounded in resilience theory, we will examine intra-individual variability (e.g., fluctuations in daily experiences) and inter-individual differences (e.g., variations within distinct groups such as those with high levels of acculturation vs. those with low levels) and possible relationships among them.
We will use multilevel modeling and group-based trajectory modeling to test the hypothesis that contextual, individual-level, and cultural factors interact to impact daily and long-term patterns of mental health outcomes among H&L ADRD caregivers.
To test this hypothesis, we propose the following aims:
1. To examine contextual, individual-level, and cultural factors that impact the day-to-day mental health experiences of H&L ADRD caregivers.
2. To characterize mental health developmental trajectories among H&L ADRD caregivers using group-based trajectory modeling.
3. To determine risk/protective factors and mental health trajectories that predict distal health outcomes among H&L ADRD caregivers.
Results from this study will inform a dynamic framework of H&L ADRD caregiver mental health by identifying modifiable intervention targets associated with resilience over time. This study represents a critical step forward in developing effective, culturally sensitive interventions to support the health and well-being of H&L ADRD caregivers who are underrepresented and underserved in the field of aging.
Hispanic and Latinx (H&L) family caregivers of individuals living with Alzheimer's Disease and Related Dementias (ADRD) are uniquely at risk for poor mental health outcomes due to increased stress associated with earlier ADRD onset and increased severity of symptoms among the H&L population.
While the link between caregiving-related stress and health outcomes is well-documented among the general ADRD caregiver population, limited knowledge on dynamic predictors of H&L ADRD caregiver mental health trajectories exists. Further, the interactions between risk/protective and cultural factors that increase resilience and reduce the risk of poor mental health outcomes over time are relatively unknown.
The purpose of this study is to investigate how interactions between contextual, individual-level, and cultural factors impact daily and long-term patterns of depression and anxiety symptoms among H&L caregivers. Using an innovative, multi-time scale design and analytical strategy grounded in resilience theory, we will examine intra-individual variability (e.g., fluctuations in daily experiences) and inter-individual differences (e.g., variations within distinct groups such as those with high levels of acculturation vs. those with low levels) and possible relationships among them.
We will use multilevel modeling and group-based trajectory modeling to test the hypothesis that contextual, individual-level, and cultural factors interact to impact daily and long-term patterns of mental health outcomes among H&L ADRD caregivers.
To test this hypothesis, we propose the following aims:
1. To examine contextual, individual-level, and cultural factors that impact the day-to-day mental health experiences of H&L ADRD caregivers.
2. To characterize mental health developmental trajectories among H&L ADRD caregivers using group-based trajectory modeling.
3. To determine risk/protective factors and mental health trajectories that predict distal health outcomes among H&L ADRD caregivers.
Results from this study will inform a dynamic framework of H&L ADRD caregiver mental health by identifying modifiable intervention targets associated with resilience over time. This study represents a critical step forward in developing effective, culturally sensitive interventions to support the health and well-being of H&L ADRD caregivers who are underrepresented and underserved in the field of aging.
Funding Goals
NOT APPLICABLE
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Birmingham,
Alabama
352940004
United States
Geographic Scope
Single Zip Code
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 387% from $643,902 to $3,135,483.
University Of Alabama At Birmingham was awarded
Hispanic & Latinx ADRD Caregiver Mental Health Study
Project Grant R01AG072569
worth $3,135,483
from National Institute on Aging in May 2022 with work to be completed primarily in Birmingham Alabama United States.
The grant
has a duration of 5 years and
was awarded through assistance program 93.866 Aging Research.
The Project Grant was awarded through grant opportunity Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional).
Status
(Ongoing)
Last Modified 6/5/26
Period of Performance
5/15/22
Start Date
4/30/27
End Date
Funding Split
$3.1M
Federal Obligation
$0.0
Non-Federal Obligation
$3.1M
Total Obligated
Activity Timeline
Transaction History
Modifications to R01AG072569
Additional Detail
Award ID FAIN
R01AG072569
SAI Number
R01AG072569-3115541693
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NN00 NIH National Insitute on Aging
Funding Office
75NN00 NIH National Insitute on Aging
Awardee UEI
YND4PLMC9AN7
Awardee CAGE
0DV74
Performance District
AL-07
Senators
Tommy Tuberville
Katie Britt
Katie Britt
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| National Institute on Aging, National Institutes of Health, Health and Human Services (075-0843) | Health research and training | Grants, subsidies, and contributions (41.0) | $1,261,370 | 100% |
Modified: 6/5/26