R01AA030156
Project Grant
Overview
Grant Description
Stage II Efficacy Trial of a Culturally Informed Brief Intervention to Reduce Alcohol-Related Health Disparities and Treatment Inequities Among Latinxs - Abstract
Our prior Stage III randomized clinical trial (N=1496) evaluating ethnic differences in response to brief intervention showed that, compared to non-Latinx whites, Latinxs were more likely to reduce alcohol use in response to standard brief alcohol interventions that are not adapted to be culturally responsive (NA-BMI) versus treatment as usual [1].
In Stage I community-based participatory research (Stage I CBPR), we developed a culturally informed brief motivational intervention (CI-BMI) which adopts a harm reduction approach and focuses on reducing alcohol problems and increasing treatment utilization [2]. Through a flexible core approach, CI-BMI introduces substantial modifications to standard brief alcohol interventions to be culturally responsive and is theoretically grounded in self-determination theory (SDT) [3-5].
The result of Stage I CBPR was CI-BMI which:
1) Leverages cultural values and strengths while addressing the process of acculturation and acculturative stress;
2) Is explicitly designed to meet the basic psychological needs of autonomy, relatedness, and competence by supporting autonomy to enhance autonomous motivation to change drinking behavior; and
3) Focuses on harm reduction.
Our Stage I CBPR (N=87) demonstrated that CI-BMI is feasible and acceptable in pretesting in a Level I trauma center [5]. We hypothesize that CI-BMI will lead to increased engagement in protective drinking behaviors, fewer alcohol problems, as well as reduce barriers to help-seeking and increase treatment utilization among underserved, non-treatment seeking Latinxs who engage in at-risk drinking and are seriously injured.
The proposed Stage II efficacy trial of CI-BMI will randomize 600 Latinxs admitted to a Level I trauma center at University Medical Center in El Paso, Texas, to either NA-BMI or CI-BMI conducted by research staff from the University of Texas El Paso. Following admission for medical treatment of an injury, eligible Latinx patients will be those who screen positive for drinking at the time of their injury or engage in at-risk drinking.
The primary aims of the proposed study are to:
1) Test the efficacy of CI-BMI in comparison to NA-BMI on alcohol-related harm reduction behaviors, alcohol problems, barriers to help-seeking, and treatment utilization among non-treatment seeking Latinxs; and
2) Examine the theoretically informed mechanism of behavior change based on SDT, including providing autonomy support to meet the basic psychological needs that enhance autonomous motivation.
Because the psychological processes underlying the intrasession mechanisms of change remain poorly understood, CI-BMI based on SDT will significantly advance the science and practice of brief interventions [6]. In addition, planned secondary data analysis will assess the influence of multi-dimensional acculturation/enculturation orientations and acculturative stress on alcohol-related outcomes.
The results of this study will lead to a theoretically informed and culturally responsive brief motivation intervention with enhanced generalizability to effectively address alcohol-related health disparities and treatment inequities among non-treatment seeking Latinxs.
Our prior Stage III randomized clinical trial (N=1496) evaluating ethnic differences in response to brief intervention showed that, compared to non-Latinx whites, Latinxs were more likely to reduce alcohol use in response to standard brief alcohol interventions that are not adapted to be culturally responsive (NA-BMI) versus treatment as usual [1].
In Stage I community-based participatory research (Stage I CBPR), we developed a culturally informed brief motivational intervention (CI-BMI) which adopts a harm reduction approach and focuses on reducing alcohol problems and increasing treatment utilization [2]. Through a flexible core approach, CI-BMI introduces substantial modifications to standard brief alcohol interventions to be culturally responsive and is theoretically grounded in self-determination theory (SDT) [3-5].
The result of Stage I CBPR was CI-BMI which:
1) Leverages cultural values and strengths while addressing the process of acculturation and acculturative stress;
2) Is explicitly designed to meet the basic psychological needs of autonomy, relatedness, and competence by supporting autonomy to enhance autonomous motivation to change drinking behavior; and
3) Focuses on harm reduction.
Our Stage I CBPR (N=87) demonstrated that CI-BMI is feasible and acceptable in pretesting in a Level I trauma center [5]. We hypothesize that CI-BMI will lead to increased engagement in protective drinking behaviors, fewer alcohol problems, as well as reduce barriers to help-seeking and increase treatment utilization among underserved, non-treatment seeking Latinxs who engage in at-risk drinking and are seriously injured.
The proposed Stage II efficacy trial of CI-BMI will randomize 600 Latinxs admitted to a Level I trauma center at University Medical Center in El Paso, Texas, to either NA-BMI or CI-BMI conducted by research staff from the University of Texas El Paso. Following admission for medical treatment of an injury, eligible Latinx patients will be those who screen positive for drinking at the time of their injury or engage in at-risk drinking.
The primary aims of the proposed study are to:
1) Test the efficacy of CI-BMI in comparison to NA-BMI on alcohol-related harm reduction behaviors, alcohol problems, barriers to help-seeking, and treatment utilization among non-treatment seeking Latinxs; and
2) Examine the theoretically informed mechanism of behavior change based on SDT, including providing autonomy support to meet the basic psychological needs that enhance autonomous motivation.
Because the psychological processes underlying the intrasession mechanisms of change remain poorly understood, CI-BMI based on SDT will significantly advance the science and practice of brief interventions [6]. In addition, planned secondary data analysis will assess the influence of multi-dimensional acculturation/enculturation orientations and acculturative stress on alcohol-related outcomes.
The results of this study will lead to a theoretically informed and culturally responsive brief motivation intervention with enhanced generalizability to effectively address alcohol-related health disparities and treatment inequities among non-treatment seeking Latinxs.
Funding Goals
NOT APPLICABLE
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
El Paso,
Texas
79968
United States
Geographic Scope
Single Zip Code
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 388% from $662,687 to $3,236,464.
The University Of Texas At El Paso was awarded
Culturally Informed Alcohol Intervention for Latinxs: Efficacy Trial
Project Grant R01AA030156
worth $3,236,464
from National Institute on Alcohol Abuse and Alcoholism in August 2022 with work to be completed primarily in El Paso Texas United States.
The grant
has a duration of 4 years 10 months and
was awarded through assistance program 93.273 Alcohol Research Programs.
The Project Grant was awarded through grant opportunity Behavioral and Integrative Treatment Development Program (R01 Clinical Trial Optional).
Status
(Ongoing)
Last Modified 6/22/26
Period of Performance
8/10/22
Start Date
6/30/27
End Date
Funding Split
$3.2M
Federal Obligation
$0.0
Non-Federal Obligation
$3.2M
Total Obligated
Activity Timeline
Subgrant Awards
Disclosed subgrants for R01AA030156
Transaction History
Modifications to R01AA030156
Additional Detail
Award ID FAIN
R01AA030156
SAI Number
R01AA030156-3343004999
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Hispanic-Serving Institution
Awarding Office
75N500 NIH National Institute on Alcohol Abuse and Alcoholism
Funding Office
75N500 NIH National Institute on Alcohol Abuse and Alcoholism
Awardee UEI
C1DEGMMKC7W7
Awardee CAGE
0MLB3
Performance District
TX-16
Senators
John Cornyn
Ted Cruz
Ted Cruz
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Health and Human Services (075-0894) | Health research and training | Grants, subsidies, and contributions (41.0) | $1,289,922 | 96% |
| Office of the Director, National Institutes of Health, Health and Human Services (075-0846) | Health research and training | Grants, subsidies, and contributions (41.0) | $57,296 | 4% |
Modified: 6/22/26