P50MH129701

The Center for Accelerating Practices to End Suicide Through Technology Translation (CAPES) - CAPES Overall: Project Summary/Abstract

Significance:
Recently, we have seen massive growth in availability of empirically supported technologies enabling suicide risk identification, monitoring, and prevention in healthcare settings. However, our knowledge of effective, efficient strategies to translate these technologies into clinical practice is weak. As a result, these technologies are not being optimally deployed to prevent suicides. The Center for Accelerating Practices to End Suicide Through Technology Translation (CAPES) will bridge this research-to-practice gap.

Investigators:
CAPES transdisciplinary faculty, advisors, and consultants have extensive expertise in the disciplines required to successfully support the CAPES mission and its individual projects, producing synergistic insights and discovery. Combined, the team has over 1,000 high-impact publications in fields relevant to or directly studying the intersection of suicide prevention, implementation science, digital health technology development and translation to practice, health disparities, study design and analysis, and healthcare systems-based change. This scientific depth will be accompanied by longitudinal engagement of diverse stakeholders.

Innovation:
CAPES will be the first NIMH center focused on accelerating evidence-based suicide care by leveraging technology solutions across multiple healthcare settings. Further, it will leverage innovations in implementation science, person-centered design, hybrid clinical trial design, technology-related economics evaluations, business development, and ethics to maximize scientific and public health impact.

Approach:
The CAPES administrative core will collaborate with the methods core to maximize the center's impact by creating synergy; prioritizing evidence-based, scalable technologies for study; creating relevance across multiple settings and diverse patient populations; leveraging the Zero Suicide framework to align with priorities of the National Action Alliance for Suicide Prevention and NIMH; and fostering business development and technology transfer to help ensure successful public dissemination, adoption, and sustainability.

Environment:
UMass and Worcester Polytechnic Institute have an established history of successfully carrying out collaborative studies and are perfectly situated to support this center. Their networked capabilities, combined with other academic, health system, business, and community partners, provide layered, complementary resource access for clinical care improvement, technology development, technology transfer from research settings to clinical use, and widespread dissemination of CAPES resources.

Impact:
Led by accomplished investigators with access to powerful resources, CAPES will be ideally situated to answer the critical research questions posed in this proposal and reach many diverse settings and patient populations. CAPES innovative embrace of evidence-based suicide care technologies, combined with a strong focus on Zero Suicide alignment, implementation science advances, technology transfer, and multi-channel dissemination, position it for transformational impact on suicide prevention in healthcare settings.

University Of Massachusetts Medical School

THE MISSION OF THE NATIONAL INSTITUTE OF MENTAL HEALTH (NIMH) IS TO TRANSFORM THE UNDERSTANDING AND TREATMENT OF MENTAL ILLNESSES THROUGH BASIC AND CLINICAL RESEARCH, PAVING THE WAY FOR PREVENTION, RECOVERY, AND CURE. WE FULFILL THIS MISSION BY SUPPORTING AND CONDUCTING RESEARCH ON MENTAL ILLNESSES, HEALTH SERVICES, AND THE UNDERLYING BASIC SCIENCE OF THE BRAIN AND BEHAVIOR; SUPPORTING THE TRAINING OF SCIENTISTS TO CARRY OUT BASIC AND CLINICAL MENTAL HEALTH RESEARCH; AND COMMUNICATING WITH SCIENTISTS, PATIENTS, PROVIDERS, AND THE PUBLIC ABOUT MENTAL HEALTH RESEARCH ADVANCES AND PRIORITIES. IN MAY 2024, NIMH RELEASED ITS STRATEGIC PLAN FOR RESEARCH. THE STRATEGIC PLAN BUILDS ON THE SUCCESSES OF PREVIOUS NIMH STRATEGIC PLANS BY PROVIDING A FRAMEWORK FOR SCIENTIFIC RESEARCH AND EXPLORATION, AND ADDRESSING NEW CHALLENGES IN MENTAL HEALTH.THE NEW STRATEGIC PLAN OUTLINES FOUR HIGH-LEVEL GOALS: GOAL 1: DEFINE THE BRAIN MECHANISMS UNDERLYING COMPLEX BEHAVIORS GOAL 2: EXAMINE MENTAL ILLNESS TRAJECTORIES ACROSS THE LIFESPAN GOAL 3: STRIVE FOR PREVENTION AND CURES GOAL 4: STRENGTHEN THE PUBLIC HEALTH IMPACT OF NIMH-SUPPORTED RESEARCH THESE FOUR GOALS FORM A BROAD ROADMAP FOR THE INSTITUTES RESEARCH PRIORITIES OVER THE NEXT FIVE YEARS, BEGINNING WITH THE FUNDAMENTAL SCIENCE OF THE BRAIN AND BEHAVIOR, AND EXTENDING THROUGH EVIDENCE-BASED SERVICES THAT IMPROVE PUBLIC HEALTH OUTCOMES.

93.242 - Mental Health Research Grants

National Institute of Mental Health (NIMH) [HHS - NIH]

Worcester, Massachusetts 01655 United States

Single Zip Code

Practice-Based Suicide Prevention Research Centers (P50 Clinical Trial Optional) (PAR-20-286)

Amendment Since initial award the total obligations have increased 287% from $3,360,660 to $12,994,321.