P20HL176204
Project Grant
Overview
Grant Description
Climate-related exposures, adaptation, and health equity (CLIMA) center - project summary (overall)
The University of Southern California (USC) Climate-related exposures, adaptation, and health equity (CLIMA) center's mission is to build a community of transdisciplinary scientists and robust research infrastructure to advance its theme of community-engaged, solution-oriented climate change (CC), adaptation, and health research.
The goal is to inform climate action policies for health equity that strengthen local adaptive capacity, reduce vulnerability, and increase resilience across the life course.
A methods development research core (MDRC) will develop innovative, highly spatiotemporally resolved models of exposure to urban heat islands, wildfire smoke, and increasingly frequent, concurrently, or consecutively occurring compound climate events and investigate their overlap with neighborhood adaptation strategies (e.g., air conditioning use, tree canopy shade, greening interventions) and vulnerabilities (power outages) to identify priorities for increasing CC resilience.
These exposure and adaptation measures will be linked to large and diverse electronic medical record (EMR) data lakes from USC-affiliated hospital systems, with novel geo-enrichment with neighborhood social and environmental determinants of health in research project 1 (RP1), and with lifetime residential histories of young adults with detailed cardiovascular health assessment starting from childhood in research project 2 (RP2).
RP1 will assess heat extremes and wildfire influenced particulate matter air pollution impact on acute heart failure hospitalization and rehospitalization risk in adults, while informing new directions in biostatistical methods.
RP2 will assess the lifetime heat stress and wildfire smoke exposures impact on cardiovascular health measures (blood pressure, pulse rate) and allostatic load as a measure of biological resilience, and as a cardiovascular risk indicator earlier in life.
The two RPs will investigate how these effects differ by social vulnerability and adaptation factors (e.g., air conditioning use, power outages, power grid resilience, urban heat islands, tree canopies, etc.).
The community engagement core (CEC) will facilitate solution-oriented translational research and multi-directional communication with policymakers and the public.
It will engage environmental justice communities using an intergenerational approach, including community participatory action research and education to engage youth in the co-design, monitoring, and ground-truthing of adaptation strategies.
The CLIMA center will create strong transdisciplinary research teams, capacity, and culture urgently needed to assess the complex, cascading impacts of CC hazards and exposures on health equity and adaptive capacity over the life course, starting with cardiovascular health and disease as a sentinel public health burden.
Given California's diverse communities and array of climate adaptation, mitigation, and health equity policies, it provides an opportunity to interrogate real-life effectiveness, co-benefits, and gaps of policies already in place; inform policies nationwide; and use CLIMA results to inform how to protect the most vulnerable and strengthen CC resiliency.
The University of Southern California (USC) Climate-related exposures, adaptation, and health equity (CLIMA) center's mission is to build a community of transdisciplinary scientists and robust research infrastructure to advance its theme of community-engaged, solution-oriented climate change (CC), adaptation, and health research.
The goal is to inform climate action policies for health equity that strengthen local adaptive capacity, reduce vulnerability, and increase resilience across the life course.
A methods development research core (MDRC) will develop innovative, highly spatiotemporally resolved models of exposure to urban heat islands, wildfire smoke, and increasingly frequent, concurrently, or consecutively occurring compound climate events and investigate their overlap with neighborhood adaptation strategies (e.g., air conditioning use, tree canopy shade, greening interventions) and vulnerabilities (power outages) to identify priorities for increasing CC resilience.
These exposure and adaptation measures will be linked to large and diverse electronic medical record (EMR) data lakes from USC-affiliated hospital systems, with novel geo-enrichment with neighborhood social and environmental determinants of health in research project 1 (RP1), and with lifetime residential histories of young adults with detailed cardiovascular health assessment starting from childhood in research project 2 (RP2).
RP1 will assess heat extremes and wildfire influenced particulate matter air pollution impact on acute heart failure hospitalization and rehospitalization risk in adults, while informing new directions in biostatistical methods.
RP2 will assess the lifetime heat stress and wildfire smoke exposures impact on cardiovascular health measures (blood pressure, pulse rate) and allostatic load as a measure of biological resilience, and as a cardiovascular risk indicator earlier in life.
The two RPs will investigate how these effects differ by social vulnerability and adaptation factors (e.g., air conditioning use, power outages, power grid resilience, urban heat islands, tree canopies, etc.).
The community engagement core (CEC) will facilitate solution-oriented translational research and multi-directional communication with policymakers and the public.
It will engage environmental justice communities using an intergenerational approach, including community participatory action research and education to engage youth in the co-design, monitoring, and ground-truthing of adaptation strategies.
The CLIMA center will create strong transdisciplinary research teams, capacity, and culture urgently needed to assess the complex, cascading impacts of CC hazards and exposures on health equity and adaptive capacity over the life course, starting with cardiovascular health and disease as a sentinel public health burden.
Given California's diverse communities and array of climate adaptation, mitigation, and health equity policies, it provides an opportunity to interrogate real-life effectiveness, co-benefits, and gaps of policies already in place; inform policies nationwide; and use CLIMA results to inform how to protect the most vulnerable and strengthen CC resiliency.
Funding Goals
TO FOSTER HEART AND VASCULAR RESEARCH IN THE BASIC, TRANSLATIONAL, CLINICAL AND POPULATION SCIENCES, AND TO FOSTER TRAINING TO BUILD TALENTED YOUNG INVESTIGATORS IN THESE AREAS, FUNDED THROUGH COMPETITIVE RESEARCH TRAINING GRANTS. SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM: TO STIMULATE TECHNOLOGICAL INNOVATION, USE SMALL BUSINESS TO MEET FEDERAL RESEARCH AND DEVELOPMENT NEEDS, FOSTER AND ENCOURAGE PARTICIPATION IN INNOVATION AND ENTREPRENEURSHIP BY SOCIALLY AND ECONOMICALLY DISADVANTAGED PERSONS, AND INCREASE PRIVATE-SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL RESEARCH AND DEVELOPMENT FUNDING. SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM: TO STIMULATE TECHNOLOGICAL INNOVATION, FOSTER TECHNOLOGY TRANSFER THROUGH COOPERATIVE R&D BETWEEN SMALL BUSINESSES AND RESEARCH INSTITUTIONS, AND INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL R&D.
Grant Program (CFDA)
Awarding Agency
Place of Performance
Los Angeles,
California
900323649
United States
Geographic Scope
Single Zip Code
University Of Southern California was awarded
Climate Change Health Research for Resilience and Equity
Project Grant P20HL176204
worth $4,107,072
from the National Institute of Environmental Health Sciences in September 2024 with work to be completed primarily in Los Angeles California United States.
The grant
has a duration of 3 years and
was awarded through assistance program 93.113 Environmental Health.
The Project Grant was awarded through grant opportunity Exploratory Grants for Climate Change and Health Research Center Development (P20 Clinical Trial Optional).
Status
(Ongoing)
Last Modified 10/4/24
Period of Performance
9/17/24
Start Date
8/31/27
End Date
Funding Split
$4.1M
Federal Obligation
$0.0
Non-Federal Obligation
$4.1M
Total Obligated
Activity Timeline
Additional Detail
Award ID FAIN
P20HL176204
SAI Number
P20HL176204-1410431818
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NH00 NIH NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Funding Office
75NV00 NIH NATIONAL INSTITUTE OF ENVIROMENTAL HEALTH SCIENCES
Awardee UEI
G88KLJR3KYT5
Awardee CAGE
1B729
Performance District
CA-34
Senators
Dianne Feinstein
Alejandro Padilla
Alejandro Padilla
Modified: 10/4/24