P20GM155896

The Center for Clinical and Translational Research at the University of South Carolina (CLINTRUSC) - Summary

The incidence of chronic diseases such as metabolic disease, cardiovascular disease, cancer, and neurodegenerative disease remain persistently high in South Carolina and are disproportionally greater in the central region of the state-called the Midlands.

The overarching goal of this Center for Translational Research Development (CTR-D) program is to address this unmet need by building a sustainable foundation of clinical and translational research capacity at the University of South Carolina (USC) which is geographically positioned in the middle of the state (Midlands), namely the Center for Clinical and Translational Research at USC- CLINTRUSC.

We will leverage existing clinical/translational research expertise within the USC School of Medicine, nationally recognized health science research within the USC School of Public Health, the School of Pharmacy, College of Nursing, and the School of Social Work, which will allow us to tap into an important research workforce that extends beyond the usual confines of academic medicine-based clinical trial infrastructure.

This also will allow us to engage meaningfully with high-risk communities that may be inaccessible or resistant to more conventional approaches.

Moreover, we will engage our health systems partners; Prisma Health (the largest health care provider in the state) and the Veterans Administration (VA) health system to develop a centralized, cohesive approach to perform clinical and translational research throughout the Midlands of South Carolina.

The CLINTRUSC program will develop the 5 essential cores required for a CTR-D which will result for the first time at USC, a cohesive infrastructure to quickly deploy clinical/translational research projects within the Midlands with a particular focus on engaging vulnerable patient populations (underserved, veterans).

University Of South Carolina

THE NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES (NIGMS) SUPPORTS BASIC RESEARCH THAT INCREASES OUR UNDERSTANDING OF BIOLOGICAL PROCESSES AND LAYS THE FOUNDATION FOR ADVANCES IN DISEASE DIAGNOSIS, TREATMENT, AND PREVENTION. NIGMS ALSO SUPPORTS RESEARCH IN SPECIFIC CLINICAL AREAS THAT AFFECT MULTIPLE ORGAN SYSTEMS: ANESTHESIOLOGY AND PERI-OPERATIVE PAIN, CLINICAL PHARMACOLOGY ?COMMON TO MULTIPLE DRUGS AND TREATMENTS, AND INJURY, CRITICAL ILLNESS, SEPSIS, AND WOUND HEALING.? NIGMS-FUNDED SCIENTISTS INVESTIGATE HOW LIVING SYSTEMS WORK AT A RANGE OF LEVELSFROM MOLECULES AND CELLS TO TISSUES AND ORGANSIN RESEARCH ORGANISMS, HUMANS, AND POPULATIONS. ADDITIONALLY, TO ENSURE THE VITALITY AND CONTINUED PRODUCTIVITY OF THE RESEARCH ENTERPRISE, NIGMS PROVIDES LEADERSHIP IN SUPPORTING THE TRAINING OF THE NEXT GENERATION OF SCIENTISTS, ENHANCING THE DIVERSITY OF THE SCIENTIFIC WORKFORCE, AND DEVELOPING RESEARCH CAPACITY THROUGHOUT THE COUNTRY.

93.859 - Biomedical Research and Research Training

National Institute of General Medical Sciences (NIGMS) [HHS - NIH]

Columbia, South Carolina 292080001 United States

Single Zip Code

Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) (PA-20-272)

Amendment Since initial award the total obligations have increased 132% from $2,199,676 to $5,108,462.