P20GM155895

The Montana Clinical and Translational Research Center - Overall Project Summary / Abstract.

With just over a million people in the entire state, Montana lacks an adequate healthcare infrastructure throughout our rural areas, contributing to significant and prevalent health disparity issues.

These issues can be directly addressed by investing in clinical and translational (C&T) research.

As noted in our letters of support, the University of Montana has numerous C&T investigators from a variety of disciplines, but uniformly working with clinical partners on C&T research is not common.

We have assembled a strong team of both clinical and public health partners (partner organizations), allowing us to not only grow C&T research capacity but also to translate research findings to our “communities,” which includes our new practice-based research network, rural clinical sites, public health / tribal health departments, and community members themselves.

Our team has extensive experience working within the clinical and translational research (CTR) funding mechanism, participating in core director roles in the Mountain West CTR infrastructure network (Mountain West CTR-IN) for the last 10 years.

In addition, we already have strong, existing relationships with clinical and public health stakeholders throughout our state.

With an evaluation plan consisting of a mixed method design, we will test the overall hypothesis that the Montana Clinical and Translational Center (Montana CTRC) will significantly build C&T research capacity in our rural and underserved state.

We will test this hypothesis through three aims:

Aim 1) Provide mentorship and workforce professional development to enhance the capacity and infrastructure in conducting C&T research,

Aim 2) Administer clinical and translational research projects, and

Aim 3) Integrate translational research within community settings.

University Of Montana

THE NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES (NIGMS) SUPPORTS BASIC RESEARCH THAT INCREASES OUR UNDERSTANDING OF BIOLOGICAL PROCESSES AND LAYS THE FOUNDATION FOR ADVANCES IN DISEASE DIAGNOSIS, TREATMENT, AND PREVENTION. NIGMS ALSO SUPPORTS RESEARCH IN SPECIFIC CLINICAL AREAS THAT AFFECT MULTIPLE ORGAN SYSTEMS: ANESTHESIOLOGY AND PERI-OPERATIVE PAIN, CLINICAL PHARMACOLOGY ?COMMON TO MULTIPLE DRUGS AND TREATMENTS, AND INJURY, CRITICAL ILLNESS, SEPSIS, AND WOUND HEALING.? NIGMS-FUNDED SCIENTISTS INVESTIGATE HOW LIVING SYSTEMS WORK AT A RANGE OF LEVELSFROM MOLECULES AND CELLS TO TISSUES AND ORGANSIN RESEARCH ORGANISMS, HUMANS, AND POPULATIONS. ADDITIONALLY, TO ENSURE THE VITALITY AND CONTINUED PRODUCTIVITY OF THE RESEARCH ENTERPRISE, NIGMS PROVIDES LEADERSHIP IN SUPPORTING THE TRAINING OF THE NEXT GENERATION OF SCIENTISTS, ENHANCING THE DIVERSITY OF THE SCIENTIFIC WORKFORCE, AND DEVELOPING RESEARCH CAPACITY THROUGHOUT THE COUNTRY.

93.859 - Biomedical Research and Research Training

National Institute of General Medical Sciences (NIGMS) [HHS - NIH]

Missoula, Montana 598120003 United States

Single Zip Code

IDeA Clinical and Translational Research Development (CTR-D) Award (P20-Clinical Trial Optional) (PAR-23-257)

Amendment Since initial award the total obligations have increased 99% from $2,179,141 to $4,332,097.