P20GM134969

Center for Biobehavioral Mechanisms of Eating Behavior - Overall Center for Bio-Behavioral Mechanisms of Eating Behavior Project Summary/Abstract

We propose to establish a Center for Bio-Behavioral Mechanisms of Eating Behavior (CBM-EB) at Sanford Research, Fargo, along with the University of North Dakota School of Medicine and North Dakota State University (NDSU). The proposed CBM-EB will initially consist of five thematically related research projects focusing on mechanisms related to eating disorders and maladaptive eating behavior.

To support the project directors of each of these five research projects, we will propose a Research Assessment Services Core comprised of a wide array of assessment methodologies that could be innovatively integrated in eating-related research. This includes assessment modalities in the area of psychopathology assessment, biological assays, neuroimaging and neurobiological assessment, eating behavior assessment, and cognitive assessment.

In addition to these core research assessment methodologies, we propose a Biomedical Statistics Core to promote scientifically valid and appropriate data collection and analyses for the study of mechanistic processes. We also propose a Human Subjects Core to support project directors in the management of regulatory aspects of human subjects research.

Additionally, we propose a Clinical Research Training Program which integrates seminars, colloquia, and close mentorship to enhance the development of our entry-level investigators. We believe that these resources will facilitate the transition of our project directors to independent investigators who conduct clinically relevant research.

Sanford Research North

THE NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES (NIGMS) SUPPORTS BASIC RESEARCH THAT INCREASES OUR UNDERSTANDING OF BIOLOGICAL PROCESSES AND LAYS THE FOUNDATION FOR ADVANCES IN DISEASE DIAGNOSIS, TREATMENT, AND PREVENTION. NIGMS ALSO SUPPORTS RESEARCH IN SPECIFIC CLINICAL AREAS THAT AFFECT MULTIPLE ORGAN SYSTEMS: ANESTHESIOLOGY AND PERI-OPERATIVE PAIN, CLINICAL PHARMACOLOGY ?COMMON TO MULTIPLE DRUGS AND TREATMENTS, AND INJURY, CRITICAL ILLNESS, SEPSIS, AND WOUND HEALING.? NIGMS-FUNDED SCIENTISTS INVESTIGATE HOW LIVING SYSTEMS WORK AT A RANGE OF LEVELSFROM MOLECULES AND CELLS TO TISSUES AND ORGANSIN RESEARCH ORGANISMS, HUMANS, AND POPULATIONS. ADDITIONALLY, TO ENSURE THE VITALITY AND CONTINUED PRODUCTIVITY OF THE RESEARCH ENTERPRISE, NIGMS PROVIDES LEADERSHIP IN SUPPORTING THE TRAINING OF THE NEXT GENERATION OF SCIENTISTS, ENHANCING THE DIVERSITY OF THE SCIENTIFIC WORKFORCE, AND DEVELOPING RESEARCH CAPACITY THROUGHOUT THE COUNTRY.

93.859 - Biomedical Research and Research Training

National Institute of General Medical Sciences (NIGMS) [HHS - NIH]

North Dakota United States

State-Wide

Centers of Biomedical Research Excellence (COBRE) Phase 1 (P20 - Clinical Trial Optional) (PAR-19-313)

Amendment Since initial award the total obligations have increased 381% from $2,390,971 to $11,511,625.