NU58DP006956
Cooperative Agreement
Overview
Grant Description
Supporting, Maintaining, and Improving the Surveillance System for Chronic Kidney Disease in the U.S. - Background
Chronic Kidney Disease (CKD) is a major public health problem affecting over 37 million US adults. This issue is compounded by low awareness, low detection and diagnosis rates, stark disparities, high morbidity, mortality, and progression to End Stage Kidney Disease (ESKD), resulting in suffering and high costs. Certain groups, such as African Americans, are at a higher risk of CKD, which is more related to social determinants of health (SDOH). The debate surrounding the use of the Black Race Coefficient in GFR estimating equations has important implications for diagnosis and surveillance. The COVID-19 pandemic has brought inequities and kidney disease into sharp focus. The CDC's CKD Surveillance Project has a serious responsibility as a comprehensive surveillance and information system for kidney disease to not just inform but also to help stimulate public health action, similar to a learning health system. Ideally, combined active and passive surveillance strategies, including collaboration, stakeholder engagement, data collection, analysis, interpretation, and robust dissemination, should provide impetus for a "prevention first" approach by raising awareness, stimulating policy changes, and improving practices.
Purpose and Aims
This proposal consists of both Component A and Component B. Our team at the University of Michigan has a proven track record in developing and maintaining national kidney disease surveillance systems. We have partnered with Duke University (Component A) and the National Kidney Foundation (Components A and B) to achieve greater impact. Our vision is not only to help maintain the current CKD surveillance system but also to substantially increase its utility and impact.
Component A (in collaboration with Component B) Aims:
(I) Procure, curate, and analyze established high-value and newer longitudinal, federal, and non-federal data sources, such as the National Center for Health Statistics (e.g., NHANES, BRFSS, 500 Cities), Medicare, Medicaid, Veterans Affairs (VA), Indian Health Service, and the Military Health System (MHS). This includes major healthcare data from claims or electronic health records, as well as data from national laboratories (e.g., Optum Labs, N3C, Clininformatics, LabCorp, etc.).
(II) Achieve greater integration and synergies with the CDC's Diabetes Surveillance System and USRDS.
(III) Track progress on Healthy People 2030-Kidney, the Advancing American Kidney Health Initiative, and Million Hearts.
(IV) Seek to inform national and regional/state population health efforts in partnership with the National Kidney Foundation.
(V) Highlight disparities in kidney disease by race/ethnicity/sex/age/geography, linking to a national grid of SDOH developed by the University of Michigan team from several publicly available sources.
(VI) Track data on COVID-19 and CKD, traditional/novel risk factors, practices, outcomes, and rare kidney diseases (e.g., ADPKD).
Component B (in collaboration with Component A)
Our core purpose is to maintain, regularly update, and enhance the existing surveillance website, building on the University of Michigan's Institute for Social Research (UM-ISR) and Inter-university Consortium for Political and Social Research's (ICPSR) experience in developing websites that feature user engagement with high-quality data and visualizations. The team will conduct user experience evaluations by engaging key stakeholders and develop specific website features and knowledge translation products for specific audiences, leveraging ICPSR's connections to over 800 universities. We will establish an iterative evaluation for continuous improvement of the website using agile methodology and improve the evaluation of the impact of this study by leveraging ICPSR's infrastructure for tracking usage and scholarly citation. Both components will implement a program evaluation and performance measurement strategy for iterative improvement.
Surveillance for Targeted Action
Our integrated Component A and B teams, purpose-driven strategy, targeted activities, extensive collaborators, robust stakeholder engagement, use of high-value data sources including SDOH, robust analytics, and innovations in dissemination are designed to take the surveillance system for chronic kidney disease to the next level.
Chronic Kidney Disease (CKD) is a major public health problem affecting over 37 million US adults. This issue is compounded by low awareness, low detection and diagnosis rates, stark disparities, high morbidity, mortality, and progression to End Stage Kidney Disease (ESKD), resulting in suffering and high costs. Certain groups, such as African Americans, are at a higher risk of CKD, which is more related to social determinants of health (SDOH). The debate surrounding the use of the Black Race Coefficient in GFR estimating equations has important implications for diagnosis and surveillance. The COVID-19 pandemic has brought inequities and kidney disease into sharp focus. The CDC's CKD Surveillance Project has a serious responsibility as a comprehensive surveillance and information system for kidney disease to not just inform but also to help stimulate public health action, similar to a learning health system. Ideally, combined active and passive surveillance strategies, including collaboration, stakeholder engagement, data collection, analysis, interpretation, and robust dissemination, should provide impetus for a "prevention first" approach by raising awareness, stimulating policy changes, and improving practices.
Purpose and Aims
This proposal consists of both Component A and Component B. Our team at the University of Michigan has a proven track record in developing and maintaining national kidney disease surveillance systems. We have partnered with Duke University (Component A) and the National Kidney Foundation (Components A and B) to achieve greater impact. Our vision is not only to help maintain the current CKD surveillance system but also to substantially increase its utility and impact.
Component A (in collaboration with Component B) Aims:
(I) Procure, curate, and analyze established high-value and newer longitudinal, federal, and non-federal data sources, such as the National Center for Health Statistics (e.g., NHANES, BRFSS, 500 Cities), Medicare, Medicaid, Veterans Affairs (VA), Indian Health Service, and the Military Health System (MHS). This includes major healthcare data from claims or electronic health records, as well as data from national laboratories (e.g., Optum Labs, N3C, Clininformatics, LabCorp, etc.).
(II) Achieve greater integration and synergies with the CDC's Diabetes Surveillance System and USRDS.
(III) Track progress on Healthy People 2030-Kidney, the Advancing American Kidney Health Initiative, and Million Hearts.
(IV) Seek to inform national and regional/state population health efforts in partnership with the National Kidney Foundation.
(V) Highlight disparities in kidney disease by race/ethnicity/sex/age/geography, linking to a national grid of SDOH developed by the University of Michigan team from several publicly available sources.
(VI) Track data on COVID-19 and CKD, traditional/novel risk factors, practices, outcomes, and rare kidney diseases (e.g., ADPKD).
Component B (in collaboration with Component A)
Our core purpose is to maintain, regularly update, and enhance the existing surveillance website, building on the University of Michigan's Institute for Social Research (UM-ISR) and Inter-university Consortium for Political and Social Research's (ICPSR) experience in developing websites that feature user engagement with high-quality data and visualizations. The team will conduct user experience evaluations by engaging key stakeholders and develop specific website features and knowledge translation products for specific audiences, leveraging ICPSR's connections to over 800 universities. We will establish an iterative evaluation for continuous improvement of the website using agile methodology and improve the evaluation of the impact of this study by leveraging ICPSR's infrastructure for tracking usage and scholarly citation. Both components will implement a program evaluation and performance measurement strategy for iterative improvement.
Surveillance for Targeted Action
Our integrated Component A and B teams, purpose-driven strategy, targeted activities, extensive collaborators, robust stakeholder engagement, use of high-value data sources including SDOH, robust analytics, and innovations in dissemination are designed to take the surveillance system for chronic kidney disease to the next level.
Funding Goals
NOT APPLICABLE
Grant Program (CFDA)
Awarding Agency
Funding Agency
Place of Performance
Michigan
United States
Geographic Scope
State-Wide
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 408% from $1,200,000 to $6,100,000.
Regents Of The University Of Michigan was awarded
Improving CKD Surveillance System in the US
Cooperative Agreement NU58DP006956
worth $6,100,000
from National Center for Chronic Disease Prevention and Health Promotion in September 2021 with work to be completed primarily in Michigan United States.
The grant
has a duration of 5 years and
was awarded through assistance program 93.135 Centers for Research and Demonstration for Health Promotion and Disease Prevention.
The Cooperative Agreement was awarded through grant opportunity Supporting and Improving the Chronic Kidney Disease Surveillance System in the United States.
Status
(Ongoing)
Last Modified 7/3/25
Period of Performance
9/30/21
Start Date
9/29/26
End Date
Funding Split
$6.1M
Federal Obligation
$0.0
Non-Federal Obligation
$6.1M
Total Obligated
Activity Timeline
Transaction History
Modifications to NU58DP006956
Additional Detail
Award ID FAIN
NU58DP006956
SAI Number
NU58DP006956-1094930615
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75CDC1 CDC Office of Financial Resources
Funding Office
75CUC0 CDC NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION
Awardee UEI
GNJ7BBP73WE9
Awardee CAGE
03399
Performance District
MI-90
Senators
Debbie Stabenow
Gary Peters
Gary Peters
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Health and Human Services (075-0948) | Health care services | Grants, subsidies, and contributions (41.0) | $2,500,000 | 100% |
Modified: 7/3/25