NU50CK000628
Cooperative Agreement
Overview
Grant Description
Minnesota Department of Health Pathogen Genomics Center of Excellence - The Minnesota Department of Health (MDH) is applying to be part of the Pathogen Genomics Center of Excellence (PGCOE) network. MDH is applying for the mandatory core and response portion, and optional education PGCOE lead portion of this funding opportunity.
The development of Advanced Molecular Detection (AMD) at the Centers for Disease Control and Prevention (CDC) and state public health laboratories over the years established a comprehensive foundation for public health infectious pathogen genomic surveillance. The COVID-19 pandemic and its shockwave revealed the urgent need to further advance AMD infrastructure and organically integrate genome data into routine public health epidemiology practice.
In addition, the pandemic amplified the long-existing disparities: health inequality in rural areas and minority populations; zoonotic disease surge rooted from climate change; food safety and insecurity due to antibiotic resistance and pandemic-driven public health workforce shortages. The projects of our PGCOE proposal, which in collaboration with our academic partners, are intended to work towards these issues.
MDH's primary academic partners are the University of Minnesota and the Mayo Clinic, where we have developed partnerships with a team of world-class scientists who will collaborate with MDH to create and apply novel genomic and bioinformatic tools to monitor and respond to a wide range of public health threats.
The diverse projects presented in this application span from new assay/workflow development to respiratory pathogen burden in rural and underserved communities, to environmental surveillance of public health pathogens, to early sentinel surveillance to minimize the threat of foodborne disease, and finally, to utilize existing educational infrastructure to culture future public health genomic laboratories and epidemiologists.
Funding is requested for MDH staff and supplies as well as for academic collaborators to carry out the proposed collaborative projects. MDH will have oversight over PGCOE activities with an external advisory committee that will ensure measures of effectiveness are met.
With the state-of-the-art existing infrastructure, pioneer scientists, laboratory technicians, epidemiologists from MDH and its long-standing academic collaborators, as well as deliberately planned projects, Minnesota PGCOE will have a state, regional, national, and international impact on the daily practice of public health in the pathogen genomic era.
The development of Advanced Molecular Detection (AMD) at the Centers for Disease Control and Prevention (CDC) and state public health laboratories over the years established a comprehensive foundation for public health infectious pathogen genomic surveillance. The COVID-19 pandemic and its shockwave revealed the urgent need to further advance AMD infrastructure and organically integrate genome data into routine public health epidemiology practice.
In addition, the pandemic amplified the long-existing disparities: health inequality in rural areas and minority populations; zoonotic disease surge rooted from climate change; food safety and insecurity due to antibiotic resistance and pandemic-driven public health workforce shortages. The projects of our PGCOE proposal, which in collaboration with our academic partners, are intended to work towards these issues.
MDH's primary academic partners are the University of Minnesota and the Mayo Clinic, where we have developed partnerships with a team of world-class scientists who will collaborate with MDH to create and apply novel genomic and bioinformatic tools to monitor and respond to a wide range of public health threats.
The diverse projects presented in this application span from new assay/workflow development to respiratory pathogen burden in rural and underserved communities, to environmental surveillance of public health pathogens, to early sentinel surveillance to minimize the threat of foodborne disease, and finally, to utilize existing educational infrastructure to culture future public health genomic laboratories and epidemiologists.
Funding is requested for MDH staff and supplies as well as for academic collaborators to carry out the proposed collaborative projects. MDH will have oversight over PGCOE activities with an external advisory committee that will ensure measures of effectiveness are met.
With the state-of-the-art existing infrastructure, pioneer scientists, laboratory technicians, epidemiologists from MDH and its long-standing academic collaborators, as well as deliberately planned projects, Minnesota PGCOE will have a state, regional, national, and international impact on the daily practice of public health in the pathogen genomic era.
Awardee
Funding Goals
NOT APPLICABLE
Grant Program (CFDA)
Awarding Agency
Place of Performance
Minnesota
United States
Geographic Scope
State-Wide
Related Opportunity
Analysis Notes
COVID-19 $7,200,000 (40%) percent of this Cooperative Agreement was funded by COVID-19 emergency acts including the American Rescue Plan Act of 2021.
Amendment Since initial award the total obligations have increased 401% from $3,600,000 to $18,039,237.
Amendment Since initial award the total obligations have increased 401% from $3,600,000 to $18,039,237.
Minnesota Department Of Health was awarded
MN Dept. of Health PGCOE: Advancing Pathogen Genomics
Cooperative Agreement NU50CK000628
worth $18,039,237
from National Center for Emerging and Zoonotic Infectious Diseases in September 2022 with work to be completed primarily in Minnesota United States.
The grant
has a duration of 5 years and
was awarded through assistance program 93.354 Public Health Emergency Response: Cooperative Agreement for Emergency Response: Public Health Crisis Response.
The Cooperative Agreement was awarded through grant opportunity US Public Health Pathogens Genomics Centers of Excellence.
Status
(Ongoing)
Last Modified 8/20/25
Period of Performance
9/30/22
Start Date
9/29/27
End Date
Funding Split
$18.0M
Federal Obligation
$0.0
Non-Federal Obligation
$18.0M
Total Obligated
Activity Timeline
Transaction History
Modifications to NU50CK000628
Additional Detail
Award ID FAIN
NU50CK000628
SAI Number
NU50CK000628-898176527
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
State Government
Awarding Office
75CDC1 CDC Office of Financial Resources
Funding Office
75CVL0 CDC NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES
Awardee UEI
DHQVY2WCVHC5
Awardee CAGE
1YBC4
Performance District
MN-90
Senators
Amy Klobuchar
Tina Smith
Tina Smith
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| CDC-Wide Activities and Program Support, Centers for Disease Control and Prevention, Health and Human Services (075-0943) | Health care services | Grants, subsidies, and contributions (41.0) | $7,200,000 | 100% |
Modified: 8/20/25