K43TW011414
Project Grant
Overview
Grant Description
Epidemiology of Malaria Invasion in Mutare City and Targets for Elimination, Zimbabwe
Project Summary/Abstract
This award will enable Dr. Sungano Mharakurwa to ascertain the epidemiological determinants of urban malaria invasion in Zimbabwe in order to identify intervention targets for restoring malaria-free status. The study will leverage an existing national malaria vector surveillance program established at Africa University in conjunction with the Ministry of Health and Child Care's National Malaria Control Program and its partners.
This work will be undertaken with guidance from an experienced team of mentors with strong complementary expertise in public health, epidemiology, transmission biology, parasite genetics, genomics, and human studies. Dr. Mharakurwa will further his career development by:
1) Conducting and directing the laboratory assays,
2) Undertaking short courses in molecular epidemiology, quantitative and sequence data analysis, translation research, conduct of clinical trials, and grant-writing, and
3) Presenting at international research conferences and writing publications.
The program will be pivotal in enabling Dr. Mharakurwa to establish a career and strong collaboration as an independent malaria researcher in Zimbabwe.
While Zimbabwe has made significant progress rolling back malaria, a serious setback of reinvasion from endemic to erstwhile malaria-free areas of the country, including highly populated cities, is emerging. The proposed research project will employ molecular and field approaches to understand the seasonal distribution, determinants, and characteristics of parasites, vectors, and humans associated with urban malaria invasion into Mutare City of Zimbabwe in order to identify strategies for reclaiming zero transmission.
Project Summary/Abstract
This award will enable Dr. Sungano Mharakurwa to ascertain the epidemiological determinants of urban malaria invasion in Zimbabwe in order to identify intervention targets for restoring malaria-free status. The study will leverage an existing national malaria vector surveillance program established at Africa University in conjunction with the Ministry of Health and Child Care's National Malaria Control Program and its partners.
This work will be undertaken with guidance from an experienced team of mentors with strong complementary expertise in public health, epidemiology, transmission biology, parasite genetics, genomics, and human studies. Dr. Mharakurwa will further his career development by:
1) Conducting and directing the laboratory assays,
2) Undertaking short courses in molecular epidemiology, quantitative and sequence data analysis, translation research, conduct of clinical trials, and grant-writing, and
3) Presenting at international research conferences and writing publications.
The program will be pivotal in enabling Dr. Mharakurwa to establish a career and strong collaboration as an independent malaria researcher in Zimbabwe.
While Zimbabwe has made significant progress rolling back malaria, a serious setback of reinvasion from endemic to erstwhile malaria-free areas of the country, including highly populated cities, is emerging. The proposed research project will employ molecular and field approaches to understand the seasonal distribution, determinants, and characteristics of parasites, vectors, and humans associated with urban malaria invasion into Mutare City of Zimbabwe in order to identify strategies for reclaiming zero transmission.
Awardee
Funding Goals
THE JOHN E. FOGARTY INTERNATIONAL CENTER (FIC) SUPPORTS RESEARCH AND RESEARCH TRAINING TO REDUCE DISPARITIES IN GLOBAL HEALTH AND TO FOSTER PARTNERSHIPS BETWEEN U.S. SCIENTISTS AND THEIR COUNTERPARTS ABROAD. FIC SUPPORTS BASIC BIOLOGICAL, BEHAVIORAL, AND SOCIAL SCIENCE RESEARCH, AS WELL AS RELATED RESEARCH TRAINING AND CAREER DEVELOPMENT. THE RESEARCH PORTFOLIO IS DIVIDED INTO SEVERAL PROGRAMS THAT SUPPORT A WIDE VARIETY OF FUNDING MECHANISMS TO MEET PROGRAMMATIC OBJECTIVES.
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Zimbabwe
Geographic Scope
Foreign
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 396% from $102,136 to $506,128.
Africa University was awarded
Malaria Epidemiology in Mutare City, Zimbabwe
Project Grant K43TW011414
worth $506,128
from Fogarty International Center in September 2021 with work to be completed primarily in Zimbabwe.
The grant
has a duration of 4 years 8 months and
was awarded through assistance program 93.989 International Research and Research Training.
The Project Grant was awarded through grant opportunity Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed).
Status
(Ongoing)
Last Modified 4/25/25
Period of Performance
9/17/21
Start Date
5/31/26
End Date
Funding Split
$506.1K
Federal Obligation
$0.0
Non-Federal Obligation
$506.1K
Total Obligated
Activity Timeline
Transaction History
Modifications to K43TW011414
Additional Detail
Award ID FAIN
K43TW011414
SAI Number
K43TW011414-2085019300
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NF00 NIH Fogarty International Center
Funding Office
75NF00 NIH Fogarty International Center
Awardee UEI
VFT2J1ZDJ988
Awardee CAGE
SNS20
Performance District
Not Applicable
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| John E. Fogarty International Center, National Institutes of Health, Health and Human Services (075-0819) | Health research and training | Grants, subsidies, and contributions (41.0) | $204,176 | 100% |
Modified: 4/25/25