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K12TR004416

Project Grant

Overview

Grant Description
CTSA K12 Program at UNC - Abstract

There is an urgent need to develop a new type of scientist, one who is motivated by a need to bring scientific advances to clinics and communities in an equitable fashion, and to make a long-term impact by contributing to health policies and research that will promote health equity. This scientist is fluent in the language of team science and collaboration and recognizes the principles that contribute to scientific translation across disciplines. This scientist brings an inclusive mindset to how they form and lead their research teams as well as the methods they use in their research. These characteristics describe a translational scientist.

Transforming translational researchers, historically trained in discipline- and disease-specific approaches, into translational scientists requires a departure from traditional career development programs. To address this need, the proposed new CTSA K12 program, the Gene Orringer Advancing Translational Science Career Development Award at the University of North Carolina at Chapel Hill (UNC-CH), will support nine early-career scholars with at least 75% protected time for research and career development activities for up to 3 years.

The objectives of the CTSA K12 are to:

1) Recruit junior faculty who are dedicated to accelerating the implementation of biomedical advances through pursuit of team-based translational science;
2) Increase recruitment efforts of scholars from underrepresented groups in biomedical sciences;
3) Provide the necessary infrastructure and protected time for scholars to develop skills in the seven translational science characteristics through mentored, didactic, and experiential learning in a format adapted to their specific needs;
4) Empower scholars with the necessary leadership, management, well-being, and resilience skills and diversity, equity, and inclusion training needed to lead diverse and inclusive research programs through didactic and experiential trainings, career coaching, and career development experiences;
5) Prepare scholars to identify and address health disparities through focused trainings and applied experiences in systems science, health equity, and community/stakeholder engagement;
6) Optimize mentoring committee-scholar relationships by requiring mentor and mentee training based on evidence-informed mentoring practices and active assessment of mentoring relationships;
7) Develop scholars into effective mentors for mentees from diverse backgrounds through didactic training and mentor skills development;
8) Integrate scholars into programs and services of the current and planned local UM1 and companion grants and the CTSA Consortium.

Our approach is to foster scholars in embracing a translational science mindset using a "cohort training model" that we have leveraged successfully at UNC, immersing scholars in the frameworks, methods, and operational principles used by their peers in other disciplines while creating a support system that encourages retention in science. CTSA K12 scholars will mature into productive and independent translational scientists that will accelerate research findings into health and societal benefits by approaching their science and leadership from a lens of equity.
Funding Goals
NOT APPLICABLE
Place of Performance
Chapel Hill, North Carolina 27599 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 200% from $1,620,000 to $4,859,730.
University Of North Carolina At Chapel Hill was awarded Equity-Focused Translational Scientist Development Program at UNC Project Grant K12TR004416 worth $4,859,730 from National Center for Advancing Translational Sciences in July 2023 with work to be completed primarily in Chapel Hill North Carolina United States. The grant has a duration of 5 years and was awarded through assistance program 93.350 National Center for Advancing Translational Sciences. The Project Grant was awarded through grant opportunity Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional).

Status
(Ongoing)

Last Modified 7/21/25

Period of Performance
7/6/23
Start Date
6/30/28
End Date
43.0% Complete

Funding Split
$4.9M
Federal Obligation
$0.0
Non-Federal Obligation
$4.9M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to K12TR004416

Transaction History

Modifications to K12TR004416

Additional Detail

Award ID FAIN
K12TR004416
SAI Number
K12TR004416-3102599936
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
75NR00 NIH National Center for Advancing Translational Sciences
Funding Office
75NR00 NIH National Center for Advancing Translational Sciences
Awardee UEI
D3LHU66KBLD5
Awardee CAGE
4B856
Performance District
NC-04
Senators
Thom Tillis
Ted Budd

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Center for Advancing Translational Sciences, National Institutes of Health, Health and Human Services (075-0875) Health research and training Grants, subsidies, and contributions (41.0) $1,620,000 100%
Modified: 7/21/25