D43TW011971
Project Grant
Overview
Grant Description
Social determinants of cardiovascular disease risk over the life course - project summary
Over the last several decades, cardiovascular disease (CVD) incidence and the prevalence of CVD risk factors have steadily increased in the Central American region, in contrast to other countries of the Americas where CVD is no longer increasing or on the decline. The rise of CVD in the region has occurred in tandem with increases in urbanization and widening social inequities, and poses a growing, untenable burden for its limited public health and health care systems.
While research in high-income countries highlights interventions on social determinants of health as levers to prevent cardiovascular disease, less is known about the specific, interventable social determinants that can help prevent CVD in Central America.
Training and mentoring of the local workforce in identifying relevant research questions, in the use of appropriate research methods, and in the dissemination of results to the scientific community, the public, and policy makers is critical to identify and develop interventions to prevent CVD in the region.
To this end, researchers from Drexel University and the Institute for Nutrition of Central America and Panama (INCAP) have partnered to establish a training program focused on developing the research capabilities of trainees and local capacity building in the conduct of policy-relevant research on the influence of social determinants and place-based factors on CVD risk across the lifespan.
Key elements include: (1) a focus on factors at multiple levels (from cities, to neighborhoods, to persons) and over the lifecourse, (2) the use of rigorous state-of-the-art methods; (3) an emphasis on the value of interdisciplinary approaches; and (4) dissemination and translation of research findings into policy actions. The program leverages the SALURBAL study, a unique multidisciplinary collaboration focused on the region.
Training activities will include (1) training of up to 3 PhD students or up to 5 Masters students; (2) support for up to 4 postdoctoral fellows and 11 visiting faculty fellows promoting the development of junior and mid-career faculty; (3) annual workshops and periodic webinars and journal clubs on social determinants of health, CVD and lifecourse epidemiology, and research methods; (4) support for the development of data management and analytical capacity on site; and (5) enhanced South-South collaborations in mentorship and research.
As a result of the program, we expect to see an increase in the number researchers with Masters or Doctoral degrees at INCAP, an increase in the number of publications and grant proposals submitted by local researchers, larger numbers of mentoring relationships, publications, and grant proposals involving collaborations between INCAP and other countries in the region, greater capacity for data management/analysis at INCAP, and greater engagement of local investigators in CVD research and dissemination activities, including policy translation in the region.
We also expect to see a continuation proposal to this training program submitted by INCAP as lead at the end of this initial phase of the program.
Over the last several decades, cardiovascular disease (CVD) incidence and the prevalence of CVD risk factors have steadily increased in the Central American region, in contrast to other countries of the Americas where CVD is no longer increasing or on the decline. The rise of CVD in the region has occurred in tandem with increases in urbanization and widening social inequities, and poses a growing, untenable burden for its limited public health and health care systems.
While research in high-income countries highlights interventions on social determinants of health as levers to prevent cardiovascular disease, less is known about the specific, interventable social determinants that can help prevent CVD in Central America.
Training and mentoring of the local workforce in identifying relevant research questions, in the use of appropriate research methods, and in the dissemination of results to the scientific community, the public, and policy makers is critical to identify and develop interventions to prevent CVD in the region.
To this end, researchers from Drexel University and the Institute for Nutrition of Central America and Panama (INCAP) have partnered to establish a training program focused on developing the research capabilities of trainees and local capacity building in the conduct of policy-relevant research on the influence of social determinants and place-based factors on CVD risk across the lifespan.
Key elements include: (1) a focus on factors at multiple levels (from cities, to neighborhoods, to persons) and over the lifecourse, (2) the use of rigorous state-of-the-art methods; (3) an emphasis on the value of interdisciplinary approaches; and (4) dissemination and translation of research findings into policy actions. The program leverages the SALURBAL study, a unique multidisciplinary collaboration focused on the region.
Training activities will include (1) training of up to 3 PhD students or up to 5 Masters students; (2) support for up to 4 postdoctoral fellows and 11 visiting faculty fellows promoting the development of junior and mid-career faculty; (3) annual workshops and periodic webinars and journal clubs on social determinants of health, CVD and lifecourse epidemiology, and research methods; (4) support for the development of data management and analytical capacity on site; and (5) enhanced South-South collaborations in mentorship and research.
As a result of the program, we expect to see an increase in the number researchers with Masters or Doctoral degrees at INCAP, an increase in the number of publications and grant proposals submitted by local researchers, larger numbers of mentoring relationships, publications, and grant proposals involving collaborations between INCAP and other countries in the region, greater capacity for data management/analysis at INCAP, and greater engagement of local investigators in CVD research and dissemination activities, including policy translation in the region.
We also expect to see a continuation proposal to this training program submitted by INCAP as lead at the end of this initial phase of the program.
Awardee
Funding Goals
THE JOHN E. FOGARTY INTERNATIONAL CENTER (FIC) SUPPORTS RESEARCH AND RESEARCH TRAINING TO REDUCE DISPARITIES IN GLOBAL HEALTH AND TO FOSTER PARTNERSHIPS BETWEEN U.S. SCIENTISTS AND THEIR COUNTERPARTS ABROAD. FIC SUPPORTS BASIC BIOLOGICAL, BEHAVIORAL, AND SOCIAL SCIENCE RESEARCH, AS WELL AS RELATED RESEARCH TRAINING AND CAREER DEVELOPMENT. THE RESEARCH PORTFOLIO IS DIVIDED INTO SEVERAL PROGRAMS THAT SUPPORT A WIDE VARIETY OF FUNDING MECHANISMS TO MEET PROGRAMMATIC OBJECTIVES.
Grant Program (CFDA)
Awarding Agency
Funding Agency
Place of Performance
Philadelphia,
Pennsylvania
19104
United States
Geographic Scope
Single Zip Code
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 457% from $248,209 to $1,382,954.
Drexel University was awarded
Social Determinants of CVD Risk in Central America
Project Grant D43TW011971
worth $1,382,954
from National Heart Lung and Blood Institute in September 2021 with work to be completed primarily in Philadelphia Pennsylvania United States.
The grant
has a duration of 4 years 10 months and
was awarded through assistance program 93.837 Cardiovascular Diseases Research.
The Project Grant was awarded through grant opportunity Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43)(Clinical Trial Optional).
Status
(Ongoing)
Last Modified 8/6/25
Period of Performance
9/1/21
Start Date
7/31/26
End Date
Funding Split
$1.4M
Federal Obligation
$0.0
Non-Federal Obligation
$1.4M
Total Obligated
Activity Timeline
Transaction History
Modifications to D43TW011971
Additional Detail
Award ID FAIN
D43TW011971
SAI Number
D43TW011971-928836626
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NF00 NIH Fogarty International Center
Funding Office
75NH00 NIH National Heart, Lung, and Blood Institute
Awardee UEI
XF3XM9642N96
Awardee CAGE
1JDU4
Performance District
PA-03
Senators
Robert Casey
John Fetterman
John Fetterman
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| National Heart, Lung, and Blood Institute, National Institutes of Health, Health and Human Services (075-0872) | Health research and training | Grants, subsidies, and contributions (41.0) | $492,419 | 77% |
| John E. Fogarty International Center, National Institutes of Health, Health and Human Services (075-0819) | Health research and training | Grants, subsidies, and contributions (41.0) | $149,904 | 23% |
Modified: 8/6/25