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D43TW011813

Project Grant

Overview

Grant Description
Support for Vector Biology Training for Sustainable Control of Vector-Borne Diseases in East Africa - Vector-Borne and Neglected Tropical Diseases (VBDS and NTDS, respectively) are endemic and emerging threats in sub-Saharan Africa (SSA).

In this renewal application, scientists from Kenya Agricultural and Livestock Research Organization, Biotechnology Research Institute (BIORI-KALRO), and Yale School of Public Health (YSPH) will partner with Kenya Medical Research Institute (KEMRI), Gulu University (GU), and Vector and Vector-Borne Diseases Institute (VVBDI) and their peers in Kenya, Uganda, and Tanzania with support of the East African Science and Technology Commission (EASTECO) to strengthen vector biology (VB) education and research capacity in order to advance vector control applications and reduce disease burden in East Africa.

Our specific objectives are to:

Aim 1) Empower early-career researchers in East Africa. Our training will target early-career scientists, including post-doctoral scholars and junior-level faculty. We will transfer knowledge necessary to advance the state-of-the-art laboratory and field research skills, mathematical modeling, and data management within broad fields of vector physiology, ecology, population genetics/genomics, and epidemiology. We will establish regional network(s) of early-career researchers in LMIC institutions to support the next generation of researchers and field practitioners and policymakers. Our program will prepare trainees with necessary skills to establish independent research programs and to advise on sustainable and evidence-based strategies for in-country vector control and disease elimination programs. We will also promote public discussions and consultations to advance downstream delivery capacity of innovative and integrated human, animal, and environmental health vector control technologies.

Aim 2) Develop leadership and institutional capacity to disseminate knowledge on innovative vector control applications. We will offer in-person and/or virtual training and mentorship opportunities in bioethics, proficient clinical and laboratory practices, vector management, and biosafety to early-career scientists from LMIC institutions. We will also train faculties in manuscript preparation, grantmanship, and editorial capabilities, and administrators in best practices for the management of research and development (R&D) activities. Working with our network institutions and public health agencies in the LMICs, we will identify and address barriers to downstream application and adoption of research outputs relevant for vector-borne and zoonotic disease control.

During the course of this award, we will support advanced training of 8-10 early-career scientists for a two-year period in LMIC institutions and present up to five workshops/webinars annually to broad program participants in different LMIC institutions. We will provide a leadership training opportunity to two advanced researchers at YSPH for 3 months annually to advance research content and mentorship/administration skills.
Funding Goals
THE JOHN E. FOGARTY INTERNATIONAL CENTER (FIC) SUPPORTS RESEARCH AND RESEARCH TRAINING TO REDUCE DISPARITIES IN GLOBAL HEALTH AND TO FOSTER PARTNERSHIPS BETWEEN U.S. SCIENTISTS AND THEIR COUNTERPARTS ABROAD. FIC SUPPORTS BASIC BIOLOGICAL, BEHAVIORAL, AND SOCIAL SCIENCE RESEARCH, AS WELL AS RELATED RESEARCH TRAINING AND CAREER DEVELOPMENT. THE RESEARCH PORTFOLIO IS DIVIDED INTO SEVERAL PROGRAMS THAT SUPPORT A WIDE VARIETY OF FUNDING MECHANISMS TO MEET PROGRAMMATIC OBJECTIVES.
Place of Performance
Kenya
Geographic Scope
Foreign
Analysis Notes
Amendment Since initial award the total obligations have increased 198% from $250,357 to $747,071.
Biotechnology Research Institute-Kalro was awarded Vector Biology Training for Sustainable Vector Control in East Africa Project Grant D43TW011813 worth $747,071 from the National Institute of Allergy and Infectious Diseases in April 2023 with work to be completed primarily in Kenya. The grant has a duration of 4 years 8 months and was awarded through assistance program 93.855 Allergy and Infectious Diseases Research. The Project Grant was awarded through grant opportunity Global Infectious Disease Research Training Program (D43 Clinical Trial Optional).

Status
(Ongoing)

Last Modified 1/21/25

Period of Performance
4/1/23
Start Date
12/31/27
End Date
58.0% Complete

Funding Split
$747.1K
Federal Obligation
$0.0
Non-Federal Obligation
$747.1K
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to D43TW011813

Transaction History

Modifications to D43TW011813

Additional Detail

Award ID FAIN
D43TW011813
SAI Number
D43TW011813-4068077288
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
State Government
Awarding Office
75NF00 NIH FOGARTY INTERNATIONAL CENTER
Funding Office
75NM00 NIH NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Awardee UEI
HUBRJWRYPME3
Awardee CAGE
SXA55
Performance District
Not Applicable

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
John E. Fogarty International Center, National Institutes of Health, Health and Human Services (075-0819) Health research and training Grants, subsidies, and contributions (41.0) $200,357 80%
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Health and Human Services (075-0885) Health research and training Grants, subsidies, and contributions (41.0) $50,000 20%
Modified: 1/21/25