D43TW011601
Project Grant
Overview
Grant Description
Research Training: Chronic Non-Communicable CVDs and Comorbidities in Peru - Project Summary
MPIs: De Las Fuentes, Lisa; Davila-Roman, Victor G.; Málaga, German; Hartinger, Stella
D43 Project Title: "Research Training: Chronic Non-Communicable CVDs and Comorbidities in Peru"
Project Start/End: 9/1/2021-8/31/2026
Chronic cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in Peru. In addition to the usual CVD risk factors, social factors such as low socioeconomic status and environmental exposure further contribute to the chronic CVD burden. Among non-communicable diseases (NCDs), high prevalence of hypertension with low rates of awareness, treatment, and control represent an important healthcare gap that contributes to CVD burden in Peru.
This application for D43 training grant represents a collaboration between US investigators (Washington University in St. Louis and Johns Hopkins University in Baltimore) and Peruvian investigators (Universidad Peruana Cayetano Heredia in Lima, Universidad Nacional del Altiplano de Puno, AB PRISMA in Lima and Puno). The D43 training program will leverage existing research projects and infrastructure in Peru to train Peruvian scientists and health professionals in chronic NCDs/CVD.
Our group has been successful in securing grant support (i.e., NIH, Gates Foundation); however, the limited number of Peruvian investigators conducting and leading NCD/CVD studies represents a significant barrier to implementing an effective and sustainable NCD/CVD research program. The proposed training program will provide support (tuition, stipend, research funds) for 14 trainees over five years: 8 master's, 4 PhD, and 2 postdoctoral Peruvian trainees and/or junior faculty.
The objectives of this structured program are to develop the research careers of trainees in the areas of chronic CVD, stroke, implementation science, and environmental exposure; to provide mentoring and support by an internationally renowned faculty with multidisciplinary expertise; and to provide opportunities for career advancement and engagement in research projects. The program will provide intensive training opportunities and build capacity in a range of scientific disciplines and skills relevant to achieving research independence.
The long-term goal of this program is to build a sustainable and collaborative research-training infrastructure to develop Peruvian research scientists capable of designing and executing interventions addressing unmet healthcare needs, including the translation of evidence-based interventions and the implementation and dissemination of effective policies to improve public health in Peru.
This application is responsive to partnering institutions of PAR-18-901 including the NHLBI (HTN/CVD), Fogarty International Center (global health and LMIC), National Institute of Aging (NCDs including CVD/HTN), National Institute of Neurological Disorders and Stroke (stroke), and National Institutes of Environmental Health Sciences (environmental exposure as risk factors for NCDs/CVD).
The ultimate goals of this D43 training program are twofold: 1) to equip outstanding junior investigators with the necessary expertise to solve challenging problems presented by the burden of chronic NCDs/CVD in Peru; and 2) to complete a full transition of program administration and leadership from the US to Peruvian MPIs, faculty, and institutions by D43 year 5.
MPIs: De Las Fuentes, Lisa; Davila-Roman, Victor G.; Málaga, German; Hartinger, Stella
D43 Project Title: "Research Training: Chronic Non-Communicable CVDs and Comorbidities in Peru"
Project Start/End: 9/1/2021-8/31/2026
Chronic cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in Peru. In addition to the usual CVD risk factors, social factors such as low socioeconomic status and environmental exposure further contribute to the chronic CVD burden. Among non-communicable diseases (NCDs), high prevalence of hypertension with low rates of awareness, treatment, and control represent an important healthcare gap that contributes to CVD burden in Peru.
This application for D43 training grant represents a collaboration between US investigators (Washington University in St. Louis and Johns Hopkins University in Baltimore) and Peruvian investigators (Universidad Peruana Cayetano Heredia in Lima, Universidad Nacional del Altiplano de Puno, AB PRISMA in Lima and Puno). The D43 training program will leverage existing research projects and infrastructure in Peru to train Peruvian scientists and health professionals in chronic NCDs/CVD.
Our group has been successful in securing grant support (i.e., NIH, Gates Foundation); however, the limited number of Peruvian investigators conducting and leading NCD/CVD studies represents a significant barrier to implementing an effective and sustainable NCD/CVD research program. The proposed training program will provide support (tuition, stipend, research funds) for 14 trainees over five years: 8 master's, 4 PhD, and 2 postdoctoral Peruvian trainees and/or junior faculty.
The objectives of this structured program are to develop the research careers of trainees in the areas of chronic CVD, stroke, implementation science, and environmental exposure; to provide mentoring and support by an internationally renowned faculty with multidisciplinary expertise; and to provide opportunities for career advancement and engagement in research projects. The program will provide intensive training opportunities and build capacity in a range of scientific disciplines and skills relevant to achieving research independence.
The long-term goal of this program is to build a sustainable and collaborative research-training infrastructure to develop Peruvian research scientists capable of designing and executing interventions addressing unmet healthcare needs, including the translation of evidence-based interventions and the implementation and dissemination of effective policies to improve public health in Peru.
This application is responsive to partnering institutions of PAR-18-901 including the NHLBI (HTN/CVD), Fogarty International Center (global health and LMIC), National Institute of Aging (NCDs including CVD/HTN), National Institute of Neurological Disorders and Stroke (stroke), and National Institutes of Environmental Health Sciences (environmental exposure as risk factors for NCDs/CVD).
The ultimate goals of this D43 training program are twofold: 1) to equip outstanding junior investigators with the necessary expertise to solve challenging problems presented by the burden of chronic NCDs/CVD in Peru; and 2) to complete a full transition of program administration and leadership from the US to Peruvian MPIs, faculty, and institutions by D43 year 5.
Funding Goals
THE JOHN E. FOGARTY INTERNATIONAL CENTER (FIC) SUPPORTS RESEARCH AND RESEARCH TRAINING TO REDUCE DISPARITIES IN GLOBAL HEALTH AND TO FOSTER PARTNERSHIPS BETWEEN U.S. SCIENTISTS AND THEIR COUNTERPARTS ABROAD. FIC SUPPORTS BASIC BIOLOGICAL, BEHAVIORAL, AND SOCIAL SCIENCE RESEARCH, AS WELL AS RELATED RESEARCH TRAINING AND CAREER DEVELOPMENT. THE RESEARCH PORTFOLIO IS DIVIDED INTO SEVERAL PROGRAMS THAT SUPPORT A WIDE VARIETY OF FUNDING MECHANISMS TO MEET PROGRAMMATIC OBJECTIVES.
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Peru
Geographic Scope
Foreign
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 395% from $251,237 to $1,243,699.
Universidad Peruana Cayetano Heredia was awarded
Peru Chronic CVD Research Training Program
Project Grant D43TW011601
worth $1,243,699
from Fogarty International Center in September 2021 with work to be completed primarily in Peru.
The grant
has a duration of 4 years 10 months and
was awarded through assistance program 93.989 International Research and Research Training.
The Project Grant was awarded through grant opportunity Change of Recipient Organization (Type 7 Parent Clinical Trial Optional).
Status
(Ongoing)
Last Modified 8/20/25
Period of Performance
9/1/21
Start Date
7/31/26
End Date
Funding Split
$1.2M
Federal Obligation
$0.0
Non-Federal Obligation
$1.2M
Total Obligated
Activity Timeline
Transaction History
Modifications to D43TW011601
Additional Detail
Award ID FAIN
D43TW011601
SAI Number
D43TW011601-3080325696
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75NF00 NIH Fogarty International Center
Funding Office
75NF00 NIH Fogarty International Center
Awardee UEI
R2CESKBNTS36
Awardee CAGE
SCE38
Performance District
Not Applicable
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| National Heart, Lung, and Blood Institute, National Institutes of Health, Health and Human Services (075-0872) | Health research and training | Grants, subsidies, and contributions (41.0) | $497,322 | 100% |
Modified: 8/20/25