CE160184

KENTUCKY CENTER FOR PRECISION MEDICINE (KCPM) CONSTRUCTION - THE UNIVERSITY OF LOUISVILLE (UOFL) IS AN INSTITUTION OF EMERGING EXCELLENCE (IEE) AND ONE OF 23 STATES DESIGNATED BY THE NATIONAL INSTITUTES OF HEALTH (NIH) AS AN INSTITUTIONAL DEVELOPMENT AWARD (IDEA) STATE, SERVING THE RESEARCH AND HEALTHCARE NEEDS OF RURAL, MEDICALLY UNDERSERVED COMMUNITIES. AS PART OF THE IDEA STATE PROGRAM, UOFL IS THE RECIPIENT OF FOUR CONCURRENT (AND MULTIPLE PAST) NIH NIGMS FUNDED CENTERS OF BIOMEDICAL RESEARCH EXCELLENCE (COBRE) PROJECTS TO TARGET LOCAL AND REGIONAL HEALTH CRISES IN KENTUCKY AND APPALACHIA, IS THE LEAD INSTITUTION FOR AN IDEA NETWORK OF BIOMEDICAL RESEARCH EXCELLENCE (INBRE), AND IS THE RECIPIENT OF AN IDEA CENTER OF TRANSLATIONAL RESEARCH PROGRAM (CTR-D). THE OVERARCHING GOAL OF THESE GRANTS IS TO IMPROVE INFRASTRUCTURE SERVING THE NEEDS OF THE COMMONWEALTH OF KENTUCKY INVESTIGATORS, WITH THE GOAL OF ACCELERATING CRITICAL BIOMEDICAL RESEARCH DISCOVERIES AND IMPROVING OVERALL HEALTH OUTCOMES. IN 2025 UOFL HAD A FEDERAL GRANT PORTFOLIO EXCEEDING $95,000,000, BUT THERE REMAIN WORKFLOW BARRIERS THAT LIMIT THE TRANSLATIONAL POTENTIAL OF THE WORK BEING PERFORMED BY THESE EXCEPTIONAL PROGRAMS THAT SLOWS THE DIRECT IMPACT THEY HAVE ON CLINICAL CARE. AS SPECIFIED IN THE CONSOLIDATED APPROPRIATIONS ACT, 2026, UOFL IS REQUESTING $12,500,000 TO RENOVATE THE TENTH FLOOR OF THE HEALTH SCIENCES CENTER (HSC) A-TOWER RESEARCH BUILDING TO ENABLE OPERATIONS OF THE NEWLY FOUNDED KENTUCKY CENTER FOR PRECISION MEDICINE, A RESEARCH CENTER DESIGNED TO SUPPORT COLLABORATIVE, INVESTIGATOR-DRIVEN TECHNOLOGY DEVELOPMENT INTEGRATED WITH A DELIBERATE IMPLEMENTATION SCIENCE PIPELINE CONNECTING MOLECULAR DISCOVERY TO CLINICAL EVALUATION. THE KCPM WILL FOCUS ON PROJECTS WITHIN FOUR SCIENTIFIC PILLARS THAT ARE BOTH UOFL AREAS OF STRENGTH AND WHERE THERE IS NEED FOR IMPROVEMENT IN PREVENTION, INNOVATIVE DIAGNOSTICS, AND NOVEL TREATMENT PARADIGMS, INCLUDING: (I) CHRONIC DISEASE AND INFLAMMATION; (II) ENVIRONMENTAL HEALTH; (III) RARE CHILDHOOD DISEASE, AND (IV) CANCER. THESE FUNDS WILL ALSO CONTRIBUTE TO THE CONSTRUCTION OF THE UOFL ADVANCED HUMAN-RELEVANT TECHNOLOGIES CORE, A KCPM PARTNER, TO SUPPORT THEIR DEVELOPMENT OF NEW APPROACH METHODOLOGIES (NAMS), WHICH WILL ENABLE GOLD-STANDARD SCIENCE AND EVIDENCE-BASED HEALTHCARE HUMAN-CENTRIC RESEARCH PROJECTS ACROSS CAMPUS. LED BY THE OFFICE OF RESEARCH AND DR. JON KLEIN, THE EXECUTIVE VICE PRESIDENT OF RESEARCH AND INNOVATION AND AN EXPERT INTERNAL TEAM OF PROJECT/CONSTRUCTION MANAGEMENT AND SCIENTIFIC STAKEHOLDERS, THIS PROJECT WILL ENABLE A COMPLETE RENOVATION OF ~8800 SQUARE FEET OF OUTDATED RESEARCH SPACE ON THE TENTH FLOOR OF THE HSC A TOWER. THIS CONSTRUCTION PLAN INCLUDES UPDATING OF ALL LABORATORY OPERATIONAL SPACE, INCORPORATION OF ENERGY EFFICIENCY FIXED EQUIPMENT TO IMPROVE RESOURCE EFFICIENCY AND UTILITY, AND DEDICATED SPACE TO SUPPORT THE QUALITY OF LIFE FOR THE TEAMS THAT WILL WORK AT THE KCPM. OVERALL, THE KCPM WILL SUPPORT LONG-TERM INSTITUTIONAL STRATEGIC PLANS AND PROVIDE MODERN IMPROVEMENTS TO OUR RESEARCH INFRASTRUCTURE, SERVING AS A BASE FOR THE DEVELOPMENT AND APPLICATION OF CUTTING-EDGE MULTIOMICS AND COMPUTATIONAL BIOLOGY SUPPORTING A BROAD RANGE OF INVESTIGATORS AND THEIR RESEARCH EFFORTS LOCALLY, REGIONALLY, NATIONALLY, AND INTERNATIONALLY. THE DISCOVERIES THAT WILL BE MADE AT THE KCPM HAVE TREMENDOUS POTENTIAL TO IMPROVE HEALTH OUTCOMES ACROSS THE COMMONWEALTH OF KENTUCKY AND BEYOND.

University Of Louisville

NOT APPLICABLE

93.493 - Congressional Directives

HRSA Office of Federal Assistance Management (OFAM) [HHS - HRSA]

Kentucky United States

State-Wide

Community Project Funding/Congressionally Directed Spending (CPF/CDS): Construction (HRSA-26-107)