C06OD037747
Project Grant
Overview
Grant Description
Spf Rhesus macaque breeding colony expansion to support HIV/AIDS-related research - Project summary / abstract
The Tulane National Primate Research Center (TNPRC) of Tulane University is one of seven National Primate Research Centers (NPRC) sponsored by the National Institutes of Health (NIH).
The TNPRC is dedicated to providing infrastructure and support for basic and applied research to advance scientific knowledge and improve human and animal health and well-being.
The TNPRC Specific Pathogen-Free (SPF) Rhesus macaque breeding colony is among the largest in the NPRC program, with a census nearing 5000, and the TNPRC AIDS research program is the largest research program at the center.
TNPRC’s SPF breeding colony serves as a national resource for NIH-funded investigators and has supplied 2155 animals for research programs across the US in the past five years, with the vast majority assigned to AIDS-related studies.
Current NPRC breeding operations cannot meet the continued high national demand for SPF Rhesus macaques.
The NIH-sponsored 2018 NHP evaluation and analysis project, designed to enhance understanding of the demand for and supply of nonhuman primates (NHPs) within the US, noted that improving infrastructure and providing support for expansion of NHP breeding colonies is necessary to ensure adequate supply of NHPs for biomedical research.
The 2023 NIH-commissioned independent National Academies of Sciences, Engineering, and Medicine (NASEM) consensus study report on nonhuman primate models in biomedical research: State of the science and future needs recognized the worsening shortage of NHP resources for NIH-sponsored research and emphasized the importance of NHP research resources in responding to US public health emergencies and advancing biomedical research.
The NASEM report concluded that the US needs to prioritize expansion of domestic NHP breeding programs.
Along with funding from the NIH, the TNPRC has committed funds and initiated projects to 1) improve the breeding colony management program and 2) expand infrastructure to meet the current and projected national demand.
A primary component of the long-term infrastructure improvement plan is to increase the number of indoor/outdoor housing facilities that will provide additional protection from inclement weather and complement existing outdoor NHP housing enclosures.
The proposed project will construct indoor/outdoor enclosures to house and breed SPF Rhesus macaques on the TNPRC breeding colony campus and provide infrastructure for current and future expansion.
These facilities will support our commitment to expand production of SPF Rhesus macaques to be used for NIH-established priority research areas (AIDS-related research) at the TNPRC and nationally.
The facilities have been designed in alignment with our long-term infrastructure improvement plan to enhance protection of animals, increase overall group housing flexibility and capacity, and provide novel and proven environmental enhancement.
The animals produced as a result of this infrastructure improvement project will help address the national shortage of SPF macaques.
The Tulane National Primate Research Center (TNPRC) of Tulane University is one of seven National Primate Research Centers (NPRC) sponsored by the National Institutes of Health (NIH).
The TNPRC is dedicated to providing infrastructure and support for basic and applied research to advance scientific knowledge and improve human and animal health and well-being.
The TNPRC Specific Pathogen-Free (SPF) Rhesus macaque breeding colony is among the largest in the NPRC program, with a census nearing 5000, and the TNPRC AIDS research program is the largest research program at the center.
TNPRC’s SPF breeding colony serves as a national resource for NIH-funded investigators and has supplied 2155 animals for research programs across the US in the past five years, with the vast majority assigned to AIDS-related studies.
Current NPRC breeding operations cannot meet the continued high national demand for SPF Rhesus macaques.
The NIH-sponsored 2018 NHP evaluation and analysis project, designed to enhance understanding of the demand for and supply of nonhuman primates (NHPs) within the US, noted that improving infrastructure and providing support for expansion of NHP breeding colonies is necessary to ensure adequate supply of NHPs for biomedical research.
The 2023 NIH-commissioned independent National Academies of Sciences, Engineering, and Medicine (NASEM) consensus study report on nonhuman primate models in biomedical research: State of the science and future needs recognized the worsening shortage of NHP resources for NIH-sponsored research and emphasized the importance of NHP research resources in responding to US public health emergencies and advancing biomedical research.
The NASEM report concluded that the US needs to prioritize expansion of domestic NHP breeding programs.
Along with funding from the NIH, the TNPRC has committed funds and initiated projects to 1) improve the breeding colony management program and 2) expand infrastructure to meet the current and projected national demand.
A primary component of the long-term infrastructure improvement plan is to increase the number of indoor/outdoor housing facilities that will provide additional protection from inclement weather and complement existing outdoor NHP housing enclosures.
The proposed project will construct indoor/outdoor enclosures to house and breed SPF Rhesus macaques on the TNPRC breeding colony campus and provide infrastructure for current and future expansion.
These facilities will support our commitment to expand production of SPF Rhesus macaques to be used for NIH-established priority research areas (AIDS-related research) at the TNPRC and nationally.
The facilities have been designed in alignment with our long-term infrastructure improvement plan to enhance protection of animals, increase overall group housing flexibility and capacity, and provide novel and proven environmental enhancement.
The animals produced as a result of this infrastructure improvement project will help address the national shortage of SPF macaques.
Funding Goals
TO RENOVATE EXISTING RESEARCH FACILITIES AND BUILD NEW RESEARCH FACILITIES TO MEET BASIC AND CLINICAL SPACE REQUIREMENTS, LABORATORY SAFETY, BIOHAZARD CONTAINMENT, AND ANIMAL CARE STANDARDS IN ORDER TO SUPPORT THE FACILITY DEMANDS OF NIH RESEARCH PROGRAMS.
Grant Program (CFDA)
Awarding Agency
Place of Performance
Covington,
Louisiana
704338915
United States
Geographic Scope
Single Zip Code
The Administrators Of Tulane Educational Fund was awarded
SPF Rhesus Macaque Breeding Colony Expansion for HIV/AIDS Research
Project Grant C06OD037747
worth $3,999,041
from the National Institute of Allergy and Infectious Diseases in September 2024 with work to be completed primarily in Covington Louisiana United States.
The grant
has a duration of 4 years 8 months and
was awarded through assistance program 93.310 Trans-NIH Research Support.
The Project Grant was awarded through grant opportunity Limited Competition: Development and Renovation of Facilities for Expanding the Breeding Capacity of Specific Pathogen Free Non-Human Primates to Support HIV/AIDS-related Research (C06 Clinical Trial Not Allowed).
Status
(Ongoing)
Last Modified 10/4/24
Period of Performance
9/17/24
Start Date
5/31/29
End Date
Funding Split
$4.0M
Federal Obligation
$0.0
Non-Federal Obligation
$4.0M
Total Obligated
Activity Timeline
Additional Detail
Award ID FAIN
C06OD037747
SAI Number
C06OD037747-2132862218
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Private Institution Of Higher Education
Awarding Office
75AGNA NIH AGGREGATE FINANCIAL ASSISTANCE DATA AWARDING OFFICE
Funding Office
75NA00 NIH OFFICE OF THE DIRECTOR
Awardee UEI
XNY5ULPU8EN6
Awardee CAGE
1BHK1
Performance District
LA-01
Senators
Bill Cassidy
John Kennedy
John Kennedy
Modified: 10/4/24