70NANB24H072
Cooperative Agreement
Overview
Grant Description
Purpose: A large population of Americans suffer from fatty liver disease. The purpose of this Phase I project is to develop an imaging procedure that will lead to more accurate measurements and diagnosis of this disease.
Activities to be performed: Activities to be performed will include conducting experiments, imaging, measurements, and tests to prove the feasibility of the research.
Expected outcomes: This research will lead to more accurate measurements and diagnosis of fatty liver disease.
Intended beneficiaries: Beneficiaries will include hospitals, clinics, medical imaging facilities, healthcare professionals, makers of imaging equipment, and academic researchers.
Subrecipient activities: The recipient plans to subaward funds to complete research in magnetic resonance imaging (MRI) and computed tomography (CT).
Activities to be performed: Activities to be performed will include conducting experiments, imaging, measurements, and tests to prove the feasibility of the research.
Expected outcomes: This research will lead to more accurate measurements and diagnosis of fatty liver disease.
Intended beneficiaries: Beneficiaries will include hospitals, clinics, medical imaging facilities, healthcare professionals, makers of imaging equipment, and academic researchers.
Subrecipient activities: The recipient plans to subaward funds to complete research in magnetic resonance imaging (MRI) and computed tomography (CT).
Awardee
Funding Goals
TO EXPLORE THE TECHNICAL MERIT OR FEASIBILITY OF AN INNOVATIVE IDEA OR TECHNOLOGY WITH THE AIM OF DEVELOPING A VIABLE PRODUCT OR SERVICE THAT WILL BE INTRODUCED TO THE COMMERCIAL MARKETPLACE. TO STRENGTHEN THE ROLE OF INNOVATIVE SMALL BUSINESS CONCERNS (SBCS) IN FEDERALLY-FUNDED RESEARCH OR RESEARCH AND DEVELOPMENT (R/R&D) AND TO: (1) STIMULATE TECHNOLOGICAL INNOVATION; (2) USE SMALL BUSINESS TO MEET FEDERAL R/R&D NEEDS; (3) FOSTER AND ENCOURAGE PARTICIPATION BY SOCIALLY AND ECONOMICALLY DISADVANTAGED SMALL BUSINESSES AND BY WOMEN-OWNED SMALL BUSINESSES IN TECHNOLOGICAL INNOVATION; AND (4) INCREASE PRIVATE SECTOR COMMERCIALIZATION OF INNOVATIONS DERIVED FROM FEDERAL R/R&D, THEREBY INCREASING COMPETITION, PRODUCTIVITY, AND ECONOMIC GROWTH.
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Madison,
Wisconsin
53719-1276
United States
Geographic Scope
Single Zip Code
Related Opportunity
Analysis Notes
Amendment Since initial award the End Date has been extended from 11/15/24 to 03/15/25.
Calimetrix was awarded
Cooperative Agreement 70NANB24H072
worth $105,284
from the National Institute of Standards and Technology in May 2024 with work to be completed primarily in Madison Wisconsin United States.
The grant
has a duration of 10 months and
was awarded through assistance program 11.620 Science, Technology, Business and/or Education Outreach.
The Cooperative Agreement was awarded through grant opportunity Small Business Innovation Research (SBIR) Program Phase I.
SBIR Details
Research Type
SBIR Phase I
Title
Multi-modality Quantitative Phantom for Magnetic Resonance Imaging and Computed Tomography Measurements of Steatotic Liver Disease
Abstract
The overall goal of this proposal is to design, develop, and test a multi-modality imaging test object (“phantom”) for quality assurance (QA) of liver fat concentration measurements by magnetic resonance imaging (MRI), computed tomography (CT), and photon counting CT (PCCT). A quantitative CT/MRI fat
phantom needs to mimic the CT and MRI signals of liver tissue across the clinically relevant range of 0-50% fat-fraction. Specifically, the proposed phantom must mimic the relationship between CT attenuation and fat-fraction observed in human liver and must replicate the critical MRI properties of liver, including MRI spectrum and relaxation properties. A phantom that could serve as a reference standard for both MRI
and CT would facilitate harmonization, ie: direct comparison of data acquired using these two prevalent imaging modalities. Cross-modality consistency is needed in clinical practice for longitudinal monitoring of patients who undergo MRI and CT over time, on multiple vendor platforms, and for multi-site research studies.
Topic Code
5
Solicitation Number
2024-NIST-SBIR-01
Status
(Complete)
Last Modified 11/21/24
Period of Performance
5/15/24
Start Date
3/15/25
End Date
Funding Split
$105.3K
Federal Obligation
$0.0
Non-Federal Obligation
$105.3K
Total Obligated
Activity Timeline
Transaction History
Modifications to 70NANB24H072
Additional Detail
Award ID FAIN
70NANB24H072
SAI Number
70NANB24H072_1
Award ID URI
EXE
Awardee Classifications
Small Business
Awarding Office
1333ND DEPT OF COMMERCE NIST
Funding Office
1333ND DEPT OF COMMERCE NIST
Awardee UEI
DF57MMBTUU55
Awardee CAGE
7UCZ9
Performance District
WI-02
Senators
Tammy Baldwin
Ron Johnson
Ron Johnson
Modified: 11/21/24