2503773
Cooperative Agreement
Overview
Grant Description
Center: NSF Center for Synthetic Organic Electrochemistry
The ability to use electrons as chemical reagents in oxidation reactions (removing electrons) or reduction reactions (adding electrons) has long held the potential to revolutionize the way in which we synthesize everything from pharmaceuticals to new materials to agricultural products.
The approach offers a simple, clean way to access new chemistry that is not available with other methods.
Yet in spite of this potential and growing interest, there remain very few cases where the approach is viable at useful scales and across a range of substrates.
For this reason, the CSOE team brings together synthetic chemists, surface chemists, electroanalytical chemists, theorists, materials scientists, and chemical engineers to understand the detailed processes that are central to removing electrons from and adding electrons to molecules.
In this way, the discoveries, new methodologies, and techniques developed in CSOE enable safer and more selective ways to build molecules in both academia and industry.
Other broader impacts include graduate and postdoctoral training in team science and entrepreneurship and outreach efforts to K-12 students and science centers.
Chemistry is one of our nation’s largest and most productive industries, and the CSOE is committed to recruiting and training the talented workforce needed for it to thrive.
The mission of the NSF Center for Synthetic Organic Electrochemistry (CSOE) is to make synthetic organic electrochemistry mainstream through the invention of enabling, green, safe, and economic new reactions and the demystification of fundamental electrochemical reactivity.
Oxidation and reduction reactions are critical steps in the production of almost all modern chemical products.
Most of these critical reactions are still done with large amounts of oxidizing and reducing agents, a situation that leads to large amounts of waste and the associated costs and safety issues associated with their removal.
Preparative electrochemical methods offer an opportunity to circumvent this problem due to their high product efficiency, mild conditions, ease of scalability, and ability to channel any waste to either benign, readily removable products or useful chemical substrates and reagents.
By integrating expertise across many areas (electrochemistry, material science, surface science, computational modeling, mechanistic analysis, and synthetic organic chemistry), CSOE is building the knowledge base, techniques, and instrumentation needed to promote widespread adoption of preparative electrochemical methods.
The center is focused on the development of new transformations that highlight to the larger community how electrochemical methods can be employed in a variety of settings and designing the instrumentation and electrochemical cells needed for that community to adopt the methods being developed.
The work requires an integrated and synergistic research environment that offers unique opportunities for undergraduate students, graduate students, and postdoctoral researchers to learn how science on the interface between different fields is best pursued.
This training is further enhanced through vibrant partnerships with industry, collaborative interdisciplinary training of scientists and engineers, and by engaging in community-wide education and outreach.
In this way, CSOE is focused on developing the new science and scientists needed for a more vibrant future.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.
Subawards are planned for this award.
The ability to use electrons as chemical reagents in oxidation reactions (removing electrons) or reduction reactions (adding electrons) has long held the potential to revolutionize the way in which we synthesize everything from pharmaceuticals to new materials to agricultural products.
The approach offers a simple, clean way to access new chemistry that is not available with other methods.
Yet in spite of this potential and growing interest, there remain very few cases where the approach is viable at useful scales and across a range of substrates.
For this reason, the CSOE team brings together synthetic chemists, surface chemists, electroanalytical chemists, theorists, materials scientists, and chemical engineers to understand the detailed processes that are central to removing electrons from and adding electrons to molecules.
In this way, the discoveries, new methodologies, and techniques developed in CSOE enable safer and more selective ways to build molecules in both academia and industry.
Other broader impacts include graduate and postdoctoral training in team science and entrepreneurship and outreach efforts to K-12 students and science centers.
Chemistry is one of our nation’s largest and most productive industries, and the CSOE is committed to recruiting and training the talented workforce needed for it to thrive.
The mission of the NSF Center for Synthetic Organic Electrochemistry (CSOE) is to make synthetic organic electrochemistry mainstream through the invention of enabling, green, safe, and economic new reactions and the demystification of fundamental electrochemical reactivity.
Oxidation and reduction reactions are critical steps in the production of almost all modern chemical products.
Most of these critical reactions are still done with large amounts of oxidizing and reducing agents, a situation that leads to large amounts of waste and the associated costs and safety issues associated with their removal.
Preparative electrochemical methods offer an opportunity to circumvent this problem due to their high product efficiency, mild conditions, ease of scalability, and ability to channel any waste to either benign, readily removable products or useful chemical substrates and reagents.
By integrating expertise across many areas (electrochemistry, material science, surface science, computational modeling, mechanistic analysis, and synthetic organic chemistry), CSOE is building the knowledge base, techniques, and instrumentation needed to promote widespread adoption of preparative electrochemical methods.
The center is focused on the development of new transformations that highlight to the larger community how electrochemical methods can be employed in a variety of settings and designing the instrumentation and electrochemical cells needed for that community to adopt the methods being developed.
The work requires an integrated and synergistic research environment that offers unique opportunities for undergraduate students, graduate students, and postdoctoral researchers to learn how science on the interface between different fields is best pursued.
This training is further enhanced through vibrant partnerships with industry, collaborative interdisciplinary training of scientists and engineers, and by engaging in community-wide education and outreach.
In this way, CSOE is focused on developing the new science and scientists needed for a more vibrant future.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.
Subawards are planned for this award.
Awardee
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "CENTERS FOR CHEMICAL INNOVATION", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF23575
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Rolla,
Missouri
65409-1330
United States
Geographic Scope
Single Zip Code
Related Opportunity
University Of Missouri System was awarded
NSF CSOE: Advancing Organic Electrochemistry
Cooperative Agreement 2503773
worth $3,800,000
from the Division of Chemistry in September 2025 with work to be completed primarily in Rolla Missouri United States.
The grant
has a duration of 5 years and
was awarded through assistance program 47.049 Mathematical and Physical Sciences.
The Cooperative Agreement was awarded through grant opportunity Centers for Chemical Innovation.
Status
(Ongoing)
Last Modified 8/21/25
Period of Performance
9/1/25
Start Date
8/31/30
End Date
Funding Split
$3.8M
Federal Obligation
$0.0
Non-Federal Obligation
$3.8M
Total Obligated
Activity Timeline
Additional Detail
Award ID FAIN
2503773
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
490309 DIVISION OF CHEMISTRY
Funding Office
490309 DIVISION OF CHEMISTRY
Awardee UEI
Y6MGH342N169
Awardee CAGE
1G2L3
Performance District
MO-08
Senators
Joshua Hawley
Eric Schmitt
Eric Schmitt
Modified: 8/21/25